Zobrazeno 1 - 7
of 7
pro vyhledávání: '"James D. Thacker"'
Autor:
James D. Thacker, Carol M. Artlett
Publikováno v:
Antioxidants & Redox Signaling. 22:1162-1175
Over the past 10 years, there has been a plethora of investigations centering on the NLRP3 inflammasome and its role in fibrosis and other disease pathologies. To date, the signaling pathways from the inflammasome to myofibroblast differentiation and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01454c95adbe098614b6d729a831ee8
https://doi.org/10.1089/ars.2014.6148
https://doi.org/10.1089/ars.2014.6148
Autor:
Carol M. Artlett, Sihem Sassi-Gaha, James D. Thacker, Beth Overley-Adamson, Connie Stephens, Ransome D Weis
Publikováno v:
Cancer Biology & Therapy
Increasing health care costs in the US are due in a large part to the increasing prevalence of chronic diseases in an aging population. Current therapeutic strategies for treating chronic diseases alleviate symptoms allowing patients to live longer w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690777854612e1874a3b33ec5a9cc0c6
https://doi.org/10.4161/cbt.27820
https://doi.org/10.4161/cbt.27820
Autor:
Carol M. Artlett, James D. Thacker
Publikováno v:
Open Journal of Immunology. :59-64
Antibiotic therapy has been of unquestionable value in terms of saving lives and reducing suffering caused by infectious diseases. However, the widespread and indiscriminant use of antibiotics has not been without significant consequences. Some of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::776d73f24fe096873d8da00bbe59813e
https://doi.org/10.4236/oji.2012.22007
https://doi.org/10.4236/oji.2012.22007
Autor:
James D. Thacker, Richard F. Rest, Brian J. Balin, Denah M. Appelt, Mitali Purohit, Carol M. Artlett, Sihem Sassi-Gaha
Publikováno v:
Antimicrobial agents and chemotherapy. 56(4)
We describe the molecular mode of action and pharmacodynamics of a new molecular entity (NME) that induces the NLRP3 inflammasome-mediated innate immune response. This innate response reduces the pathogen load in an experimentally induced methicillin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb82b4cabe723618b116ffff3575e610
https://pubmed.ncbi.nlm.nih.gov/22290938
https://pubmed.ncbi.nlm.nih.gov/22290938
Autor:
Susan T. Hingley, Juliana Zoga, Corey M. Caruthers, Elizabeth K. Ruszak, James D. Thacker, Brian J. Balin, Denah M. Appelt
Publikováno v:
Alzheimer's & Dementia. 6
Our laboratory has been studying the role of infection with the obligate intracellular bacterium, Chlamydia pneumoniae, in sporadic late-onset Alzheimer disease (LOAD). This infection may be a trigger for the pathology observed in LOAD as a function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48c2336816ae5432cf5fb333571e5394
https://doi.org/10.1016/j.jalz.2010.05.880
https://doi.org/10.1016/j.jalz.2010.05.880
Autor:
James D. Thacker, Sihem Sassi-Gaha, Richard F. Rest, Mitali Purohit, Carol M. Artlett, Martyn A. Brown
Publikováno v:
Journal of natural products. 72(11)
Experiments were undertaken to isolate a component of the serum of goat (Capra hircus) that is effective at mediating an innate immune response. This report describes the isolation and structure elucidation of 1-(N-acetyl-ALYDKGYTSKEQKDCVGI)-2-arachi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0611819962aea0e1148c64cd8211a775
https://pubmed.ncbi.nlm.nih.gov/19835390
https://pubmed.ncbi.nlm.nih.gov/19835390
Publikováno v:
NACD Directorship. Oct/Nov2011, Vol. 37 Issue 5, p8-8. 1p.