Zobrazeno 1 - 4
of 4
pro vyhledávání: '"James D. Surmeier"'
Autor:
Sherri L. Thiele, Betty Chen, Charlotte Lo, Tracey S. Gertler, Ruth Warre, James D. Surmeier, Jonathan M. Brotchie, Joanne E. Nash
Publikováno v:
Neurobiology of Disease, Vol 71, Iss , Pp 334-344 (2014)
Parkinsonian symptoms arise due to over-activity of the indirect striatal output pathway, and under-activity of the direct striatal output pathway. l-DOPA-induced dyskinesia (LID) is caused when the opposite circuitry problems are established, with t
Externí odkaz:
https://doaj.org/article/0e3d4e4c5e6e4ecd84c9c2d0a22e3be0
Autor:
Joanne E. Nash, Betty Chen, Sherri L. Thiele, Ruth Warre, Charlotte Lo, Tracey S. Gertler, James D. Surmeier, Jonathan M. Brotchie
Publikováno v:
Neurobiology of Disease, Vol 71, Iss, Pp 334-344 (2014)
Parkinsonian symptoms arise due to over-activity of the indirect striatal output pathway, and under-activity of the direct striatal output pathway. l -DOPA-induced dyskinesia (LID) is caused when the opposite circuitry problems are established, with
Publikováno v:
Mitochondrial Dysfunction in Neurodegenerative Disorders ISBN: 9783319286358
One of the defining features of Parkinson’s disease (PD) is its sparsely distributed pathology. This chapter explores the hypothesis that this selective vulnerability can be traced back to an unusual neuronal phenotype. This phenotype is best exemp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6570a1f90ed3f76ad62f8c966ceea036
https://doi.org/10.1007/978-3-319-28637-2_6
https://doi.org/10.1007/978-3-319-28637-2_6
Autor:
Bashar M. Mullah, Julian P. Jolly, James D. Surmeier, Qin Wang, Clare Bergson, Janet D. Robishaw, Michael S. Lidow
Publikováno v:
The Journal of biological chemistry. 276(42)
The D(1) dopamine receptor, G protein gamma(7) subunit, and adenylylcyclase are selectively expressed in the striatum, suggesting their potential interaction in a common signaling pathway. To evaluate this possibility, a ribozyme strategy was used to