Zobrazeno 1 - 10
of 26
pro vyhledávání: '"James D. Nicholson"'
Publikováno v:
Frontiers in Neurology, Vol 5 (2014)
Externí odkaz:
https://doaj.org/article/207cf6907d1148d9aca8db48e0a203bc
Autor:
Shalom Michowiz, Dana Morzaev, Nitza Goldenberg-Cohen, Tamar Azrad-Lebovitz, Neelan J. Marianayagam, Alon Zahavi, Moran Friedman, Myles Brookman, Edith Hochhauser, James D. Nicholson
Publikováno v:
Current eye research. 44(5)
Purpose To determine whether Toll-like receptor 4 knockout protects mice from corneal neovascularization following chemical injury compared to wild-type (WT) mice. Methods A chemical burn (75% silver nitrate, 25% potassium nitrate) was created under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b4858cf37dd9eba965bcf0d381ebdc
https://pubmed.ncbi.nlm.nih.gov/30595046
https://pubmed.ncbi.nlm.nih.gov/30595046
Autor:
Leonardo H. Tonelli, Sarah M. Clark, Chang Song, Achsah D. Keegan, Xin Li, James D. Nicholson
Publikováno v:
Brain, Behavior, and Immunity. 57:161-172
The concept of the brain as an immune privileged organ is rapidly evolving in light of new findings outlining the sophisticated relationship between the central nervous and the immune systems. The role of T cells in brain development and function, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc99ae4b8b9e02fd4fff4059c3001521
https://doi.org/10.1016/j.bbi.2016.03.017
https://doi.org/10.1016/j.bbi.2016.03.017
Autor:
Edith Hochhauser, Shirel Weiss, Dana Morzaev, Tomm Caspi, Nitza Goldenberg-Cohen, James D. Nicholson
Publikováno v:
Clinical & Experimental Ophthalmology. 43:655-665
Background This study aims to investigate the role of the inflammatory response following optic nerve crush (ONC) in knockout mice for the toll-like receptor-4 gene (TLR4−/−) compared to wild-type (WT) mice. Methods ONC was induced in TLR4−/−
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89ce61c5ac035c44b20514e3601ff332
https://doi.org/10.1111/ceo.12521
https://doi.org/10.1111/ceo.12521
Autor:
Kelley J. Murphy, Chang Song, Robert Schwarcz, Leonardo H. Tonelli, James D. Nicholson, Sarah M. Clark, Chloe N. Vaughn, Gloria E. Hoffman, Ta-Chung M. Mou
Kynurenic acid, a metabolite of the kynurenine pathway of tryptophan degradation, acts as an endogenous antagonist of alpha7 nicotinic and NMDA receptors and is implicated in a number of neurophysiological and neuropathological processes including co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685cea37f674c8ac985b07eafb85d189
https://europepmc.org/articles/PMC5766363/
https://europepmc.org/articles/PMC5766363/
Autor:
Shirel Weiss, David Zadok, Nitza Goldenberg-Cohen, Orit Barinfeld, Alon Zahavi, James D. Nicholson, Orkun Muhsinoglu, Mark Vieyra
Publikováno v:
Investigative Opthalmology & Visual Science. 60:1987
Purpose To investigate the potential neuroprotective effect of sildenafil on the ocular circulation in mice with/without optic nerve crush (ONC). Methods Male adult mice (n = 63) were treated with intravitreal (IVT) sildenafil 24 μg/3 μL, intraperi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da78f291a929539988eda1a30c95c5b
https://doi.org/10.1167/iovs.18-26333
https://doi.org/10.1167/iovs.18-26333
Autor:
Robert P. McMahon, Sarah M. Clark, John W. Stiller, Robert Schwarcz, James D. Nicholson, Thomas M. Hyde, Patricia Langenberg, Leonardo H. Tonelli, Joel E. Kleinman, Francesca M. Notarangelo, Teodor T. Postolache, Ana Pocivavsek
Publikováno v:
Journal of psychiatryneuroscience : JPN. 41(6)
Background: Neuroinflammatory processes are increasingly believed to participate in the pathophysiology of a number of major psychiatric diseases, including depression. Immune activation stimulates the conversion of the amino acid tryptophan to kynur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63181f2df238dd8f5eb16933b48d3132
https://pubmed.ncbi.nlm.nih.gov/27070351
https://pubmed.ncbi.nlm.nih.gov/27070351
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0148855 (2016)
PLoS ONE
PLoS ONE
Ischemia-reperfusion injury after central nervous system (CNS) injury presents a major health care challenge with few promising treatments. Recently, it has become possible to reduce edema after CNS injury by antagonizing a sulfonylurea receptor 1 (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3939228fd44ac7eb43834b66144ae6e2
http://europepmc.org/articles/PMC4999058?pdf=render
http://europepmc.org/articles/PMC4999058?pdf=render
Autor:
Peggy S. Zelenka, Samuel J. Listwak, Dolena R. Ledee, Leonardo H. Tonelli, Svetlana P. Chapoval, Chad Gunsolly, James D. Nicholson, Daniela Verthelyi, Achsah D. Keegan
Publikováno v:
Journal of Neuroimmunology. 225:82-90
The chemokine CCL27 has chemoattractant properties for memory T cells and has been implicated in skin allergic reactions. The present study reports the expression in the brain of two CCL27 splice variants localized in the cerebral cortex and limbic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d39b8e7c668b693209ab3634d2c65f
https://doi.org/10.1016/j.jneuroim.2010.04.019
https://doi.org/10.1016/j.jneuroim.2010.04.019
Autor:
Edith Hochhauser, Nitza Goldenberg-Cohen, Dennis Pushkov, Shirel Weiss, Shalom Michowiz, James D. Nicholson, Moshe Ben Hemou, Ivan Novitzky
Publikováno v:
The International journal of neuroscience. 126(2)
To examine the effects of hyperbaric oxygen (HBO) therapy and knockout of toll-like receptor 4 (TLR4) on the outcome of temporary middle cerebral artery occlusion (MCAO) in a mouse model.MCAO was induced in anesthetized male C57Bl/6 mice (WT) and TLR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2036d05c63c56eda9e6bddf25bee0bfe
https://pubmed.ncbi.nlm.nih.gov/25562174
https://pubmed.ncbi.nlm.nih.gov/25562174