Zobrazeno 1 - 10
of 21
pro vyhledávání: '"James D. Jentsch"'
Autor:
Arshad H. Khan, Jared R. Bagley, Nathan LaPierre, Carlos Gonzalez-Figueroa, Tadeo C. Spencer, Mudra Choudhury, Xinshu Xiao, Eleazar Eskin, James D. Jentsch, Desmond J. Smith
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112856- (2023)
Summary: To identify addiction genes, we evaluate intravenous self-administration of cocaine or saline in 84 inbred and recombinant inbred mouse strains over 10 days. We integrate the behavior data with brain RNA-seq data from 41 strains. The self-ad
Externí odkaz:
https://doaj.org/article/76106c85485d410382c1b263021a215e
Autor:
Jared R. Bagley, Lauren S. Bailey, Leona H. Gagnon, Hao He, Vivek M. Philip, Laura G. Reinholdt, Lisa M. Tarantino, Elissa J. Chesler, James D. Jentsch
Publikováno v:
Addiction Neuroscience, Vol 4, Iss , Pp 100045- (2022)
Impulsive behavior and impulsivity are heritable phenotypes that are strongly associated with risk for substance use disorders. Identifying the neurogenetic mechanisms that influence impulsivity may also reveal novel biological insights into addictio
Externí odkaz:
https://doaj.org/article/8d7ae0d3eb4240ea808588b686a11961
Autor:
Sarah A. Schoenrock, Leona Gagnon, Ashley Olson, Michael Leonardo, Vivek M. Philip, Hao He, Laura G. Reinholdt, Stacey J. Sukoff Rizzo, James D. Jentsch, Elissa J. Chesler, Lisa M. Tarantino
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Cocaine use and overdose deaths attributed to cocaine have increased significantly in the United States in the last 10 years. Despite the prevalence of cocaine use disorder (CUD) and the personal and societal problems it presents, there are currently
Externí odkaz:
https://doaj.org/article/41d4f62f80874b009ee9b8e8ee035d32
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Klinefelter syndrome (KS; 47, XXY) and Turner syndrome (TS; 45, XO) are caused by two relatively common sex chromosome aneuploidies. These conditions are associated with an increased odds of neuropsychiatric disorders, including attention deficit/hyp
Externí odkaz:
https://doaj.org/article/b7f94dfccdc84d0da95f5bc33131cfe1
Autor:
Yao-Ying Ma, Sandy M. Henley, Jeff Toll, James D. Jentsch, Christopher J. Evans, Michael S. Levine, Carlos Cepeda
Publikováno v:
ASN Neuro, Vol 5 (2013)
To examine the mechanisms of drug relapse, we first established a model for cocaine IVSA (intravenous self-administration) in mice, and subsequently examined electrophysiological alterations of MSNs (medium-sized spiny neurons) in the NAc (nucleus ac
Externí odkaz:
https://doaj.org/article/376ee972bfa349f9a9db289903ffc8dc
Autor:
Lauren S. Bailey, Jared R. Bagley, James D. Wherry, Elissa J. Chesler, Anushree Karkhanis, James D. Jentsch, Lisa M. Tarantino
Publikováno v:
Psychopharmacology. 240:561-573
Autor:
Arshad H. Khan, Jared R. Bagley, Nathan LaPierre, Carlos Gonzalez-Figueroa, Tadeo C. Spencer, Mudra Choudhury, Xinshu Xiao, Eleazar Eskin, James D. Jentsch, Desmond J. Smith
To identify genetic pathways for addiction, we analyzed intravenous self-administration of cocaine or saline in a panel of 84 inbred and recombinant inbred mouse strains over 10 days. We integrated the behavior data with RNA-Seq data from the medial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88d2a06bb0e9271b9b96b21669deac40
https://doi.org/10.1101/2022.11.10.516062
https://doi.org/10.1101/2022.11.10.516062
Publikováno v:
Addiction biology, vol 27, iss 3
Addict Biol
Addict Biol
Cocaine self-administration is a complexly determined trait, with a substantial proportion of individual differences being determined by genetic variation. However, the relevant genetic variants that drive heritable differences in cocaine use remain
Autor:
Jared R. Bagley, Lauren S. Bailey, Leona H. Gagnon, Hao He, Vivek M. Philip, Laura G. Reinholdt, Lisa M. Tarantino, Elissa J. Chesler, James D. Jentsch
Impulsive behavior and impulsivity are heritable phenotypes that are strongly associated with risk for substance use disorders in human subjects. Consequently, identifying the neurogenetic mechanisms that influence impulsivity may also reveal novel b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a9a104d81b61acc54b24906b6d9d4c
https://doi.org/10.1101/2022.01.29.478259
https://doi.org/10.1101/2022.01.29.478259
Autor:
Ivona Pandrea, James D. Jentsch, Cassandra Benjamin, Nelson B. Freimer, Jen Chieh Lee, Tianyu He, Maurice Newton, Anna J. Jasinska, Giovanni Coppola
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific reports, vol 10, iss 1
Psychosocial stressors - life events that challenge social support and relationships - represent powerful risk factors for human disease; included amongst these events are relocation, isolation and displacement. To evaluate the impact of a controlled