Zobrazeno 1 - 10
of 19
pro vyhledávání: '"James D. Hatton"'
Publikováno v:
Journal of Neurosurgery. 82:847-857
✓ Our earlier investigations of the biology of the epidermal growth factor receptor (EGFR) in human gliomas demonstrated that the level of EGFR expression did not directly predict the glioma growth response to EGF, suggesting that the function of t
Publikováno v:
Glia. 9:113-119
Fetal and neonatal astrocytes migrate in specific patterns when transplanted into the adult rat host brain. However, it is unclear whether these astrocytes demonstrate the same degree of mobility during early brain development. In the present study,
Publikováno v:
Glia. 9:18-24
While transplanted astrocytes migrate in specific patterns in therecip-ient brains, it is not known whether native astrocytes behave similarly. The ability of normal astrocytes to migrate under non-transplant condition was therefore explored. Native
Autor:
H. Galera, Isabel Rodríguez-Moldes, C.E. Rexroad, Fernando Carceller, James D. Hatton, L.A. Salo, Carla Palumbo, Dirk Adriaensen, S. Palazzini, G. Norton, Pedro Cuevas, O. Rönning, Giovanni Tredici, G. De Wef, Gutierrez Marin, Araceli Jimenez, Friedrich Anderhuber, Hoi Sang U, Robert K. Fucher, M.H.A. de Groodt-Lasseel, C. Streffer, Gianpaolo Papaccio, I. Katzeff, Lars L. Andersen, Gastone Marotti, Akira Ikeda, Giuliano Pizzini, Diana Reimers, Davide Zaffe, M. A. Konerding, M. Nieminen, R.H. Renegar, F. Steinberg, B.A. Stein, I. Barajon, I. Sanguineti, Shin Matsumoto, P. Bullón, Dietrich W. Scheuermann, C. Rosendorff, Vincenzo Esposito, Andreas Weiglein, M. Larmas, Ramón Anadón, J.-P. Timmermans
Publikováno v:
Cells Tissues Organs. 137:I-V
Publikováno v:
Journal of neurosurgery. 89(6)
Object. The relationship between glial fibrillary acidic protein (GFAP) expression and glial tumor cell behavior has not been well defined. The goal of this study was to examine this relationship further. Methods. To investigate the relationship betw
Publikováno v:
Journal of neurosurgery. 88(1)
Object. The aim of the study was to assess the pluripotential central nervous system (CNS) progenitor cells that give rise to the many differentiated neuronal and glial cell types of the adult mammalian brain and the role of peptide growth factors su
Publikováno v:
Journal of neurosurgery. 82(5)
✓ The epidermal growth factor receptor (EGFR) gene is amplified in over 40% of primary human glioblastomas and overexpressed in the majority. The authors' investigations demonstrate that the function of the EGFR in glioblastomas is distinct from th
Autor:
U Hoi Sang, James D. Hatton
Publikováno v:
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 11(5)
Neonatal rat astrocytes transplanted into the rat cerebrum migrate extensively. However, few of the molecular signals determining this migration have been defined. In the present study, in vitro modifications were designed to examine whether differen
Autor:
James D. Hatton, Luo Lin
Publikováno v:
Journal of neuroscience methods. 45(3)
beta-Galactosidase activity as illuminated by the indigogenic X-gal staining method has been used to demonstrate the presence of genetically modified cells carrying the reporter gene lacZ, coding for the E. coli enzyme. Endogenous activity has been a
Publikováno v:
Glia. 5(4)
Neonatal rat cortical astrocytes migrate extensively after transplantation into the brains of adult hosts. However, the effects of cues provided by different sources of donor astrocytes and by different target sites of implantation on this migration