Výsledky vyhledávání - "James D. Gumkowski"

Analysis of RNA Methylation by Phylogenetically Diverse Cfr Radical S-Adenosylmethionine Enzymes Reveals an Iron-Binding Accessory Domain in a Clostridial Enzyme

Autor: Squire J. Booker, Ryan J. Martinie, Carsten Krebs, Matthew R. Bauerle, Mohamed Almarei, James D. Gumkowski, Patrick S. Corrigan, Alexey Silakov, Juan Pan, Amie K. Boal

Publikováno v: Biochemistry. 58:3169-3184

Cfr is a radical S-adenosylmethionine (SAM) RNA methylase linked to multidrug antibiotic resistance in bacterial pathogens. It catalyzes a chemically challenging C-C bond-forming reaction to methylate C8 of A2503 (Escherichia coli numbering) of 23S r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7c9590ed60eae307acd7841e8f2ed44
https://doi.org/10.1021/acs.biochem.9b00197

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Analysis of RNA Methylation by Phylogenetically Diverse Cfr Radical

Autor: James D, Gumkowski, Ryan J, Martinie, Patrick S, Corrigan, Juan, Pan, Matthew R, Bauerle, Mohamed, Almarei, Squire J, Booker, Alexey, Silakov, Carsten, Krebs, Amie K, Boal

Publikováno v: Biochemistry

Cfr is a radical S-adenosylmethionine (SAM) RNA methylase linked to multi-drug antibiotic resistance in bacterial pathogens. It catalyzes a chemically challenging C-C-bond forming reaction to methylate C8 of A2503 [Escherichia coli (Ec) numbering) of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::79c386cf30fbc6dcbffbd07ca389d436
https://pubmed.ncbi.nlm.nih.gov/31246421

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