Zobrazeno 1 - 10
of 57
pro vyhledávání: '"James D. Evans"'
Autor:
Shabih Shakeel, James D. Evans, Mark Hazelbaker, C. Cheng Kao, Robert C. Vaughan, Sarah J. Butcher
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Human parechoviruses (HPeV) are picornaviruses with a highly-ordered RNA genome contained within icosahedrally-symmetric capsids. Ordered RNA structures have recently been shown to interact with capsid proteins VP1 and VP3 and facilitate vir
Externí odkaz:
https://doaj.org/article/c61882b4e82648e0b67f4e7c833cfd5e
Autor:
Robert C. Vaughan, James D. Evans, Mark Hazelbaker, C. Cheng Kao, Shabih Shakeel, Sarah J. Butcher
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
Human parechoviruses (HPeV) are picornaviruses with a highly-ordered RNA genome contained within icosahedrally-symmetric capsids. Ordered RNA structures have recently been shown to interact with capsid proteins VP1 and VP3 and facilitate virus assemb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41409453ba0dc43dce2e345c63364ac1
https://doaj.org/article/c61882b4e82648e0b67f4e7c833cfd5e
https://doaj.org/article/c61882b4e82648e0b67f4e7c833cfd5e
Autor:
Eva Frei, David H. Phillips, Daniel W. Nebert, František Bárta, Kateřina Levová, Volker M. Arlt, Zhanquan Shi, Heinz H. Schmeiser, James D. Evans, Marie Stiborová
Publikováno v:
Chemical Research in Toxicology. 24:1710-1719
Exposure to aristolochic acid I (AAI) is associated with aristolochic acid nephropathy, Balkan endemic nephropathy, and urothelial cancer. Individual differences in xenobiotic-metabolizing enzyme activities are likely to be a reason for interindividu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa35ba827ceb0f87957513fa0decb720
https://doi.org/10.1021/tx200259y
https://doi.org/10.1021/tx200259y
Publikováno v:
Nucleic Acids Research
Retrotransposition amplifies LINE-1 (L1) to high copy number in mammalian genomes. The L1 protein encoded by ORF1 (ORF1p) is required for retrotransposition. This dependence on ORF1p was investigated by mutating three highly conserved residues, R238,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4651da6a7c580ccaac483deff4d0d297
https://doi.org/10.1093/nar/gkr171
https://doi.org/10.1093/nar/gkr171
Autor:
James D. Evans, David H. Phillips, Eva Frei, C. Roland Wolf, Peter B. Farmer, Marie Stiborová, Volker M. Arlt, Gonçalo Gamboa da Costa, Colin J. Henderson, Rajinder Singh
Publikováno v:
Drug Metabolism and Disposition
2-Amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine (PhIP), formed during the cooking of foods, induces colon cancer in rodents. PhIP is metabolically activated by cytochrome P450s (CYPs). In order to evaluate the role of hepatic CYPs in the bioactivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad06a3d35127533d784f765faf44b7d9
Autor:
Philip J. Brown, F. Daniel, John P. Neoptolemos, Clem W. Imrie, Azadeh Stark, Joseph C. Carmichael, Colin D. Johnson, John A. C. Buckels, James D. Evans
Publikováno v:
Scopus-Elsevier
British Journal of Cancer
British Journal of Cancer
Pancreatic cancer has a poor response to conventional chemotherapy and radiotherapy. Inhibition of matrix metalloproteinase activity involved in tumour invasion and metastases is a novel biological approach for cancer treatment. This multicentre phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a36e42f9953074322b6546969aeb44
https://doi.org/10.1054/bjoc.2001.2168
https://doi.org/10.1054/bjoc.2001.2168
Publikováno v:
Digestive Surgery. 17:407-410
Gastrointestinal autonomic nerve sarcomas are rare tumours. A 36-year-old man presented with abdominal pain, distension and constipation. Abdominal ultrasound and CT scanning demonstrated a giant cystic intra-abdominal mass. Laparotomy confirmed a la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707e56086d436b360661bd8ae8525979
https://doi.org/10.1159/000018889
https://doi.org/10.1159/000018889
Publikováno v:
Digestive Surgery. 17:183-187
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d66a63fa110fd32563d818ffcc0669a
https://doi.org/10.1159/000018828
https://doi.org/10.1159/000018828
Autor:
Paula Ghaneh, Nicholas R. Lemoine, Sigmund Dawiskiba, Anthony Kawesha, Fiona Campbell, Åke Andrén-Sandberg, John P. Neoptolemos, Dagfinn Ögraed, Robert Skar, James D. Evans
Publikováno v:
International Journal of Cancer. 89:469-474
Previous studies of molecular prognostic markers following resection for exocrine pancreatic cancer have produced conflicting results. Our aim was to undertake a comprehensive analysis of potentially useful molecular markers in a large, multicentre p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56a5cf9057972c68534fe0ead44a290
https://doi.org/10.1002/1097-0215(20001120)89:6<469::aid-ijc1>3.0.co
https://doi.org/10.1002/1097-0215(20001120)89:6<469::aid-ijc1>3.0.co
Autor:
John P. Neoptolemos, James D. Evans, Andrew Dodson, Alan Woolfenden, K F Parsons, Christopher S. Foster, Philip Cornford
Publikováno v:
The American Journal of Pathology. 154:137-144
Expression of protein kinase C (PKC) isoenzymes -alpha, -beta, -delta, -epsilon, -gamma, -iota, -lambda, -mu, -theta, and -zeta, and of their common receptor for activated C-kinase (RACK)-1, was determined immunohistochemically using specific antibod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e620924097d7fcd312d7b2b51ceb987d
https://doi.org/10.1016/s0002-9440(10)65260-1
https://doi.org/10.1016/s0002-9440(10)65260-1