Zobrazeno 1 - 10
of 33
pro vyhledávání: '"James D San Antonio"'
Autor:
J Des Parkin, James D San Antonio, Anton V Persikov, Hayat Dagher, Raymond Dalgleish, Shane T Jensen, Xavier Jeunemaitre, Judy Savige
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0175582 (2017)
Collagen III is critical to the integrity of blood vessels and distensible organs, and in hemostasis. Examination of the human collagen III interactome reveals a nearly identical structural arrangement and charge distribution pattern as for collagen
Externí odkaz:
https://doaj.org/article/958b23c874db42d29f3955a5ae78635a
Autor:
James D San Antonio, Mary H Schweitzer, Shane T Jensen, Raghu Kalluri, Michael Buckley, Joseph P R O Orgel
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20381 (2011)
Eleven collagen peptide sequences recovered from chemical extracts of dinosaur bones were mapped onto molecular models of the vertebrate collagen fibril derived from extant taxa. The dinosaur peptides localized to fibril regions protected by the clos
Externí odkaz:
https://doaj.org/article/74608424e5534a7d8f329ffdb7b4f4ad
Publikováno v:
Bioengineering
Bioengineering, Vol 8, Iss 3, p 3 (2021)
Bioengineering, Vol 8, Iss 3, p 3 (2021)
Type I collagen, the predominant protein of vertebrates, assembles into fibrils that orchestrate the form and function of bone, tendon, skin, and other tissues. Collagen plays roles in hemostasis, wound healing, angiogenesis, and biomineralization, a
Crucial Role for Endothelial Cell α2β1 Integrin Receptor Clustering in Collagen-Induced Angiogenesis
Autor:
Kevin R. Turner, Hans Deckmyn, James D. San Antonio, Christopher S. Adams, Stephanie Staelens
Publikováno v:
Anatomical record (Hoboken, N.J. : 2007)Literature Cited. 303(6)
Angiogenesis is a crucial mechanism of vascular growth and regeneration that requires biosynthesis and cross-linking of collagens in vivo and is induced by collagen in vitro. Here, we use an in vitro model in which apical Type I collagen gels rapidly
Autor:
Raymond Dalgleish, Hayat Dagher, J. Des Parkin, Shane T. Jensen, Judy Savige, Anton V. Persikov, James D. San Antonio, Xavier Jeunemaitre
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0175582 (2017)
PLoS ONE
PLoS ONE
Collagen III is critical to the integrity of blood vessels and distensible organs, and in hemostasis. Examination of the human collagen III interactome reveals a nearly identical structural arrangement and charge distribution pattern as for collagen
Autor:
J. Des Parkin, Shane T. Jensen, Billy G. Hudson, Judy Savige, Vadim Pedchenko, James D. San Antonio
Publikováno v:
Human Mutation. 32:127-143
Collagen IV is the major protein found in basement membranes. It comprises three heterotrimers (α1α1α2, α3α4α5, and α5α5α6) that form distinct networks, and are responsible for membrane strength and integrity.We constructed linear maps of th
Autor:
Kristin L. Reigle, Gloria Di Lullo, Kevin R. Turner, Jerold A. Last, Inna Chervoneva, David E. Birk, James L. Funderburgh, Elizabeth Elrod, Markus W. Germann, Charles Surber, Ralph D. Sanderson, James D. San Antonio
Publikováno v:
Journal of Cellular Biochemistry. 104:1684-1698
Non-enzymatic glycation of type I collagen occurs in aging and diabetes, and may affect collagen solubility, charge, polymerization, and intermolecular interactions. Proteoglycans(1) (PGs) bind type I collagen and are proposed to regulate fibril asse
Autor:
Olga Antipova, Shiamalee Perumal, Steven Chen, Wayne A. Cabral, James D. San Antonio, Joseph P. R. O. Orgel, Kevin R. Turner, Joan C. Marini, Antonella Forlino, Leena Ala-Kokko, Jon McAuliffe, Andrzej Fertala, Gloria A. Di Lullo, Shawn M. Sweeney, Aileen M. Barnes
Publikováno v:
Journal of Biological Chemistry. 283:21187-21197
Type I collagen, the predominant protein of vertebrates, polymerizes with type III and V collagens and non-collagenous molecules into large cable-like fibrils, yet how the fibril interacts with cells and other binding partners remains poorly understo
Publikováno v:
Blood. 103:1356-1363
Patients given unfractionated heparin (UFH) or low-molecular-weight heparin (LMWH) for prophylaxis or treatment of thrombosis sometimes suffer serious bleeding. We showed previously that peptides containing 3 or more tandem repeats of heparin-binding
Publikováno v:
Journal of Biological Chemistry. 278:4238-4249
Perlecan, a ubiquitous basement membrane heparan sulfate proteoglycan, plays key roles in blood vessel growth and structural integrity. We discovered that the C terminus of perlecan potently inhibited four aspects of angiogenesis: endothelial cell mi