Feasibility, acceptability, and limited efficacy of health system-led familial risk notification: protocol for a mixed-methods evaluation

Autor: Paula R. Blasi, Aaron Scrol, Melissa L. Anderson, Marlaine Figueroa Gray, Brooks Tiffany, Stephanie M. Fullerton, James D. Ralston, Kathleen A. Leppig, Nora B. Henrikson

Publikováno v: Pilot and Feasibility Studies, Vol 8, Iss 1, Pp 1-9 (2022)

Abstract Background Genetic testing for pathogenic variants associated with hereditary breast and ovarian cancer risk can improve cancer outcomes through enhanced preventive care in both people with known variants and their biologic relatives. Cascad

Externí odkaz: https://doaj.org/article/0402aec9ec8d44ae8ba5113e4976e02b

Associations Between Different Self-reported Social Risks and Neighborhood-level Resources in Medicaid Patients

Autor: Chris Miller-Rosales, Jodi McCloskey, Connie S. Uratsu, James D. Ralston, Elizabeth A. Bayliss, Richard W. Grant

Publikováno v: Medical care. 60(8)

Adverse social conditions are a key contributor to health disparities. Improved understanding of how social risk factors interact with each other and with neighborhood characteristics may inform efforts to reduce health disparities.A questionnaire of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7a4e4f4c46b7d2f28e4895a240cd1a
https://pubmed.ncbi.nlm.nih.gov/35640038

Increase in the Rate of Gut Carriage of Fluoroquinolone-ResistantEscherichia colidespite a Reduction in Antibiotic Prescriptions

Autor: Veronika Tchesnokova, Lydia Larson, Irina Basova, Yulia Sledneva, Debarati Choudhury, Thalia Solyanik, Jennifer Heng, Teresa Christina Bonilla, Sophia Pham, Ellen M. Schartz, Lawrence T. Madziwa, Erika Holden, Scott J. Weissman, James D. Ralston, Evgeni V. Sokurenko

BackgroundFluoroquinolone use for urinary tract infections has been steadily declining. Gut microbiota is the main reservoir for uropathogenicEscherichia colibut whether the carriage of fluoroquinolone-resistantE. colihas been changing is unknown.Met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e427d0227c54061160d2ff175412d6f
https://doi.org/10.1101/2022.12.16.22283539

Neptune: an environment for the delivery of genomic medicine

Autor: Venner Eric, Victoria Yi, David Murdock, Sara E. Kalla, Tsung-Jung Wu, Aniko Sabo, Shoudong Li, Qingchang Meng, Xia Tian, Mullai Murugan, Michelle Cohen, Christie Kovar, Wei-Qi Wei, Wendy K. Chung, Chunhua Weng, Georgia L. Wiesner, Gail P. Jarvik, Donna Muzny, Richard A. Gibbs, Debra Abrams, Samuel E. Adunyah, Ladia Albertson-Junkans, Berta Almoguera, Darren C. Ames, Paul Appelbaum, Samuel Aronson, Sharon Aufox, Lawrence J. Babb, Adithya Balasubramanian, Hana Bangash, Melissa Basford, Lisa Bastarache, Samantha Baxter, Meckenzie Behr, Barbara Benoit, Elizabeth Bhoj, Suzette J. Bielinski, Sarah T. Bland, Carrie Blout, Kenneth Borthwick, Erwin P. Bottinger, Mark Bowser, Harrison Brand, Murray Brilliant, Wendy Brodeur, Pedro Caraballo, David Carrell, Andrew Carroll, Lisa Castillo, Victor Castro, Gauthami Chandanavelli, Theodore Chiang, Rex L. Chisholm, Kurt D. Christensen, Wendy Chung, Christopher G. Chute, Brittany City, Beth L. Cobb, John J. Connolly, Paul Crane, Katherine Crew, David R. Crosslin, Jyoti Dayal, Mariza De Andrade, Jessica De la Cruz, Josh C. Denny, Shawn Denson, Tim DeSmet, Ozan Dikilitas, Michael J. Dinsmore, Sheila Dodge, Phil Dunlea, Todd L. Edwards, Christine M. Eng, David Fasel, Alex Fedotov, Qiping Feng, Mark Fleharty, Andrea Foster, Robert Freimuth, Christopher Friedrich, Stephanie M. Fullerton, Birgit Funke, Stacey Gabriel, Vivian Gainer, Ali Gharavi, Andrew M. Glazer, Joseph T. Glessner, Jessica Goehringer, Adam S. Gordon, Chet Graham, Robert C. Green, Justin H. Gundelach, Heather S. Hain, Hakon Hakonarson, Maegan V. Harden, John Harley, Margaret Harr, Andrea Hartzler, M. Geoffrey Hayes, Scott Hebbring, Nora Henrikson, Andrew Hershey, Christin Hoell, Ingrid Holm, Kayla M. Howell, George Hripcsak, Jianhong Hu, Elizabeth Duffy Hynes, Joy C. Jayaseelan, Yunyun Jiang, Yoonjung Yoonie Joo, Sheethal Jose, Navya Shilpa Josyula, Anne E. Justice, Divya Kalra, Elizabeth W. Karlson, Brendan J. Keating, Melissa A. Kelly, Eimear E. Kenny, Dustin Key, Krzysztof Kiryluk, Terrie Kitchner, Barbara Klanderman, Eric Klee, David C. Kochan, Viktoriya Korchina, Leah Kottyan, Emily Kudalkar, Alanna Kulchak Rahm, Iftikhar J. Kullo, Philip Lammers, Eric B. Larson, Matthew S. Lebo, Magalie Leduc, Ming Ta (Michael) Lee, Niall J. Lennon, Kathleen A. Leppig, Nancy D. Leslie, Rongling Li, Wayne H. Liang, Chiao-Feng Lin, Jodell E. Linder, Noralane M. Lindor, Todd Lingren, James G. Linneman, Cong Liu, Wen Liu, Xiuping Liu, John Lynch, Hayley Lyon, Alyssa Macbeth, Harshad Mahadeshwar, Lisa Mahanta, Bradley Malin, Teri Manolio, Maddalena Marasa, Keith Marsolo, Michelle L. McGowan, Elizabeth McNally, Jim Meldrim, Frank Mentch, Hila Milo Rasouly, Jonathan Mosley, Shubhabrata Mukherjee, Thomas E. Mullen, Jesse Muniz, David R. Murdock, Shawn Murphy, Melanie F. Myers, Bahram Namjou, Yizhao Ni, Robert C. Onofrio, Aniwaa Owusu Obeng, Thomas N. Person, Josh F. Peterson, Lynn Petukhova, Cassandra J. Pisieczko, Siddharth Pratap, Cynthia A. Prows, Megan J. Puckelwartz, Ritika Raj, James D. Ralston, Arvind Ramaprasan, Andrea Ramirez, Luke Rasmussen, Laura Rasmussen-Torvik, Soumya Raychaudhuri, Heidi L. Rehm, Marylyn D. Ritchie, Catherine Rives, Beenish Riza, Dan M. Roden, Elisabeth A. Rosenthal, Avni Santani, Schaid Dan, Steven Scherer, Stuart Scott, Aaron Scrol, Soumitra Sengupta, Ning Shang, Himanshu Sharma, Richard R. Sharp, Rajbir Singh, Patrick M.A. Sleiman, Kara Slowik, Joshua C. Smith, Maureen E. Smith, Duane T. Smoot, Jordan W. Smoller, Sunghwan Sohn, Ian B. Stanaway, Justin Starren, Mary Stroud, Jessica Su, Casey Overby Taylor, Kasia Tolwinski, Sara L. Van Driest, Sean M. Vargas, Matthew Varugheese, David Veenstra, Eric Venner, Miguel Verbitsky, Gina Vicente, Michael Wagner, Kimberly Walker, Theresa Walunas, Liwen Wang, Qiaoyan Wang, Scott T. Weiss, Quinn S. Wells, Peter S. White, Ken L. Wiley, Janet L. Williams, Marc S. Williams, Michael W. Wilson, Leora Witkowski, Laura Allison Woods, Betty Woolf, Julia Wynn, Yaping Yang, Ge Zhang, Lan Zhang, Hana Zouk

Publikováno v: Genetics in medicine : official journal of the American College of Medical Genetics

Genomic medicine holds great promise for improving health care, but integrating searchable and actionable genetic data into electronic health records (EHRs) remains a challenge. Here we describe Neptune, a system for managing the interaction between

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46ee0a24725b676d6fd75db54d7666bc
https://doi.org/10.1038/s41436-021-01230-w

Aligning care with the personal values of patients with complex care needs

Autor: James D. Ralston, Andrew L. Berry, Richard W. Grant, Jennifer Barrow, Thomas Delate, Kathy Gleason, Marlaine Figueroa Gray, Leah Tuzzio, Connie S. Uratsu, Zoë A. Bermet, Elizabeth A. Bayliss

Publikováno v: Health Serv Res

Objective To identify opportunities to align care with the personal values of patients from three distinct groups with complex medical, behavioral, and social needs. Data sources/study setting Between June and August 2019, we conducted semi-structure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c254c8d486b960f03b7c97a8735e4e
https://doi.org/10.1111/1475-6773.13862