Zobrazeno 1 - 10
of 60
pro vyhledávání: '"James D, Cooper"'
Autor:
Shreya Das Sharma, Bharath Kumar Reddy, Rakhi Pal, Tuula E. Ritakari, James D. Cooper, Bhuvaneish T. Selvaraj, Peter C. Kind, Siddharthan Chandran, David J.A. Wyllie, Sumantra Chattarji
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112344- (2023)
Summary: Pre-clinical studies of fragile X syndrome (FXS) have focused on neurons, with the role of glia remaining largely underexplored. We examined the astrocytic regulation of aberrant firing of FXS neurons derived from human pluripotent stem cell
Externí odkaz:
https://doaj.org/article/07393c8817104f9e9f38c64e50f84baa
Autor:
Leah Schembs, Ariane Willems, Kerstin Hasenpusch-Theil, James D. Cooper, Katie Whiting, Karen Burr, Sunniva M.K. Bøstrand, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Thomas Theil
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110811- (2022)
Summary: Defects in primary cilia, cellular antennas that control multiple intracellular signaling pathways, underlie several neurodevelopmental disorders, but it remains unknown how cilia control essential steps in human brain formation. Here, we sh
Externí odkaz:
https://doaj.org/article/bdacfe54fbb54aa281ae7e58ff835c24
Autor:
Alessandra Granata, Ioannis Kasioulis, Felipe Serrano, James D. Cooper, Matthew Traylor, Sanjay Sinha, Hugh S. Markus
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
A common variant in the Histone Deacetylase 9 (HDAC9) gene is the strongest genetic risk for large-vessel stroke, and HDAC9 offers a novel target for therapeutic modulation. However, the mechanisms linking the HDAC9 variant with increased stroke risk
Externí odkaz:
https://doaj.org/article/be8fb247debe4d449c933c6d5f7b9b5c
Autor:
Jamie Toombs, Lindsay Panther, Loren Ornelas, Chunyan Liu, Emilda Gomez, Raquel Martín-Ibáñez, Simon R. Cox, Stuart J. Ritchie, Sarah E. Harris, Adele Taylor, Paul Redmond, Tom C. Russ, Lee Murphy, James D. Cooper, Karen Burr, Bhuvaneish T. Selvaraj, Cathy Browne, Clive N. Svendsen, Sally A. Cowley, Ian J. Deary, Siddharthan Chandran, Tara L. Spires-Jones, Dhruv Sareen
Publikováno v:
Stem Cell Research, Vol 46, Iss , Pp 101851- (2020)
Cognitive decline is among the most feared aspects of ageing. We have generated induced pluripotent stem cells (iPSCs) from 24 people from the Lothian Birth Cohort 1936, whose cognitive ability was tested in childhood and in older age. Peripheral blo
Externí odkaz:
https://doaj.org/article/2ec95fdbbd9044aca4c3416f0ee6b4db
Publikováno v:
Blood Advances.
Rates of pulmonary embolism (PE) in children have steadily increased over the past two decades. Patient outcomes following hospital discharge are poorly understood, and many patients experience recurrent or persistent chest pain or dyspnea, prompting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a62f00d0431c0274e1856d4ac7e416e0
https://doi.org/10.1182/bloodadvances.2022009062
https://doi.org/10.1182/bloodadvances.2022009062
Autor:
Julie Jaffray, Maua Mosha, Brian Branchford, Neil A. Goldenberg, Michael Silvey, Stacy E. Croteau, John H. Fargo, James D. Cooper, Nihal Bakeer, Amy Stillings, Emily Krava, Guy Young, Ernest K. Amankwah
Publikováno v:
Journal of Thrombosis and Haemostasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ce7d116ff3d6fd336ddfaf8d2faa46a
https://doi.org/10.1016/j.jtha.2023.03.045
https://doi.org/10.1016/j.jtha.2023.03.045
Autor:
Neil A. Goldenberg, Anh Thy H. Nguyen, Arash Mahajerin, Emily Krava, Guy Young, James D. Cooper, Ernest K. Amankwah, Michael Silvey, Brian R. Branchford, Stacy E. Croteau, E. Vincent S. Faustino, John H. Fargo, Neil A. Zakai, Julie Jaffray, Nihal Bakeer, Amy Stillings
Publikováno v:
Pediatr Crit Care Med
Objectives To create a risk model for hospital-acquired venous thromboembolism in critically ill children upon admission to an ICU. Design Case-control study. Setting ICUs from eight children's hospitals throughout the United States. Subjects Critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440edc27ab8ada937d158c0ae130b0f6
https://doi.org/10.1097/pcc.0000000000002826
https://doi.org/10.1097/pcc.0000000000002826
Autor:
Dana Egan-Sherry, James D. Cooper
Publikováno v:
Blood. 140:8464-8464
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2de86629420089a163b93c9d5ff7d177
https://doi.org/10.1182/blood-2022-156823
https://doi.org/10.1182/blood-2022-156823
Autor:
Willems A, Thomas Theil, James D. Cooper, Kerstin Hasenpusch-Theil, Schembs L, Siddharthan Chandran, Whiting K, Sunniva M. K. Bøstrand, Karen Burr, Bhuvaneish T. Selvaraj
Publikováno v:
Cell Reports. 39:110811
SUMMARYDefects in primary cilia, cellular antennas that controls multiple intracellular signalling pathways, underlie several neurodevelopmental disorders, but how cilia control essential steps in human brain formation remains elusive. Here, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fb83c4ac2a81ea6d0b629dd96dd0f36
https://doi.org/10.1016/j.celrep.2022.110811
https://doi.org/10.1016/j.celrep.2022.110811
Autor:
Loren Ornelas, Paul Redmond, Simon R. Cox, Cathy Browne, Siddharthan Chandran, Emilda Gomez, Jamie Toombs, Adele M. Taylor, Lindsay Panther, Chunyan Liu, Ian J. Deary, Tara L. Spires-Jones, Karen Burr, Sally A. Cowley, Stuart J. Ritchie, Bhuvaneish T. Selvaraj, Sarah E. Harris, Tom C. Russ, Dhruv Sareen, Lee Murphy, Clive N. Svendsen, Raquel Martín-Ibáñez, James D. Cooper
Publikováno v:
Stem Cell Research
Stem Cell Research, Vol 46, Iss, Pp 101851-(2020)
Stem Cell Research, Vol 46, Iss, Pp 101851-(2020)
Cognitive decline is among the most feared aspects of ageing. We have generated induced pluripotent stem cells (iPSCs) from 24 people from the Lothian Birth Cohort 1936, whose cognitive ability was tested in childhood and in older age. Peripheral blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ce392dbba0e112d23a41c2cc9a1058
https://doi.org/10.1016/j.scr.2020.101851
https://doi.org/10.1016/j.scr.2020.101851
