Zobrazeno 1 - 10
of 532
pro vyhledávání: '"James D, Brooks"'
Autor:
Ru M. Wen, Zhengyuan Qiu, G. Edward W. Marti, Eric E. Peterson, Fernando Jose Garcia Marques, Abel Bermudez, Yi Wei, Rosalie Nolley, Nathan Lam, Alex LaPat Polasko, Chun-Lung Chiu, Dalin Zhang, Sanghee Cho, Grigorios Marios Karageorgos, Elizabeth McDonough, Chrystal Chadwick, Fiona Ginty, Kyeong Joo Jung, Raghu Machiraju, Parag Mallick, Laura Crowley, Jonathan R. Pollack, Hongjuan Zhao, Sharon J. Pitteri, James D. Brooks
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background Loss of AZGP1 expression is a biomarker associated with progression to castration resistance, development of metastasis, and poor disease-specific survival in prostate cancer. However, high expression of AZGP1 cells in prostate ca
Externí odkaz:
https://doaj.org/article/5a28bfe2f761406aa6383b764b9fb5d0
Autor:
Okyaz Eminaga, Mahmoud Abbas, Christian Kunder, Yuri Tolkach, Ryan Han, James D. Brooks, Rosalie Nolley, Axel Semjonow, Martin Boegemann, Robert West, Jin Long, Richard E. Fan, Olaf Bettendorf
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-30 (2024)
Abstract Prostate cancer pathology plays a crucial role in clinical management but is time-consuming. Artificial intelligence (AI) shows promise in detecting prostate cancer and grading patterns. We tested an AI-based digital twin of a pathologist, v
Externí odkaz:
https://doaj.org/article/378b253abe26462a92e7ddbdb8d64e5c
Autor:
Fernando Garcia-Marques, Keely Fuller, Abel Bermudez, Nikhiya Shamsher, Hongjuan Zhao, James D. Brooks, Mark R. Flory, Sharon J. Pitteri
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Glycoproteins in urine have the potential to provide a rich class of informative molecules for studying human health and disease. Despite this promise, the urine glycoproteome has been largely uncharacterized. Here, we present the analysis o
Externí odkaz:
https://doaj.org/article/a59c996315e54c0a8cea97c2a56c91bd
Autor:
Shiqin Liu, Sarah J. Hawley, Christian A. Kunder, En-Chi Hsu, Michelle Shen, Lennart Westphalen, Heidi Auman, Lisa F. Newcomb, Daniel W. Lin, Peter S. Nelson, Ziding Feng, Maria S. Tretiakova, Lawrence D. True, Funda Vakar-Lopez, Peter R. Carroll, Jeffry Simko, Martin E. Gleave, Dean A. Troyer, Jesse K. McKenney, James D. Brooks, Michael A. Liss, Tanya Stoyanova
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Distinguishing indolent from clinically significant localized prostate cancer is a major clinical challenge and influences clinical decision-making between treatment and active surveillance. The development of novel predictive biomarkers wil
Externí odkaz:
https://doaj.org/article/71e4a4bb78964d77b74c7c002f70c24d
Autor:
Alice Guan, Eduardo J. Santiago-Rodríguez, Benjamin I. Chung, Janet K. Shim, Laura Allen, Mei-Chin Kuo, Kathie Lau, Zinnia Loya, James D. Brooks, Iona Cheng, Mindy C. DeRouen, Dominick L. Frosch, Todd Golden, John T. Leppert, Daphne Y. Lichtensztajn, Qian Lu, Debora Oh, Weiva Sieh, Michelle Wadhwa, Matthew R. Cooperberg, Peter R. Carroll, Scarlett L. Gomez, Salma Shariff-Marco
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Patients diagnosed with low-risk prostate cancer (PCa) are confronted with a difficult decision regarding whether to undergo definitive treatment or to pursue an active surveillance protocol. This is potentially further complicate
Externí odkaz:
https://doaj.org/article/aabab07a25854885916d582e6006fec5
Publikováno v:
Cancer Medicine, Vol 12, Iss 16, Pp 17475-17490 (2023)
Abstract Background The understanding of the factors causing decreased overall survival (OS) in older patients compared to younger patients in lung adenocarcinoma (LUAD) remains. Methods Gene expression profiles of LUAD were obtained from publicly av
Externí odkaz:
https://doaj.org/article/c758fe93fb0f4b1cb30d1142b6b400dc
Autor:
Grigorios M. Karageorgos, Sanghee Cho, Elizabeth McDonough, Chrystal Chadwick, Soumya Ghose, Jonathan Owens, Kyeong Joo Jung, Raghu Machiraju, Robert West, James D. Brooks, Parag Mallick, Fiona Ginty
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2024)
Introduction: Prostate cancer is a highly heterogeneous disease, presenting varying levels of aggressiveness and response to treatment. Angiogenesis is one of the hallmarks of cancer, providing oxygen and nutrient supply to tumors. Micro vessel densi
Externí odkaz:
https://doaj.org/article/76f90f0b38a84f9db5dcbdb0a5e42308
Autor:
James D Brooks, Nicholas Riley, Ru Wen, Jessica Stark, George E Marti, Hongjuan Zhao, Carolyn R Bertozzi, Sharon Pitteri
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f197a25b362b4c9db0b4e53d4fc102b9
Autor:
Alice Guan, Janet K. Shim, Laura Allen, Mei‐Chin Kuo, Kathie Lau, Zinnia Loya, James D. Brooks, Peter R. Carroll, Iona Cheng, Benjamin I. Chung, Mindy C. DeRouen, Dominic L. Frosch, Todd Golden, John T. Leppert, Daphne Y. Lichtensztajn, Qian Lu, Debora L. Oh, Weiva Sieh, Michelle Wadhwa, Scarlett L. Gomez, Salma Shariff‐Marco
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 6307-6317 (2023)
Abstract Background Factors that influence prostate cancer treatment decisions are complex, multifaceted, and personal, and may vary by race/ethnicity. Although research has been published to quantify factors involved in decision‐making, these stud
Externí odkaz:
https://doaj.org/article/448ee299723f420fba154596a26a5042
Autor:
Lauren Brady, Lisa F. Newcomb, Kehao Zhu, Yingye Zheng, Hilary Boyer, Navonil De Sarkar, Jesse K. McKenney, James D. Brooks, Peter R. Carroll, Atreya Dash, William J. Ellis, Christopher P. Filson, Martin E. Gleave, Michael A. Liss, Frances Martin, Todd M. Morgan, Ian M. Thompson, Andrew A. Wagner, Colin C. Pritchard, Daniel W. Lin, Peter S. Nelson
Publikováno v:
Cancer Medicine, Vol 11, Iss 22, Pp 4332-4340 (2022)
Abstract Background Pathogenic germline mutations in several rare penetrant cancer predisposition genes are associated with an increased risk of aggressive prostate cancer (PC). Our objectives were to determine the prevalence of pathogenic germline m
Externí odkaz:
https://doaj.org/article/7d57484662bd4dfa80fce8215691bd68