Zobrazeno 1 - 10
of 449
pro vyhledávání: '"James D, Berry"'
Autor:
Ruth Luthi-Carter, Sara Cappelli, Morgan Le Roux-Bourdieu, Noemie Tentillier, James P. Quinn, Tiziana Petrozziello, Lathika Gopalakrishnan, Purva Sethi, Himanshi Choudhary, Giorgia Bartolini, Elias Gebara, Cristiana Stuani, Laure Font, Jiyan An, Vanessa Ortega, Jessica Sage, Edina Kosa, Bianca A. Trombetta, Roberto Simeone, Tamara Seredenina, Tariq Afroz, James D. Berry, Steven E. Arnold, Becky C. Carlyle, Oskar Adolfsson, Ghazaleh Sadri-Vakili, Emanuele Buratti, Robert Bowser, Abdulbaki Agbas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract The TAR DNA Binding Protein 43 (TDP-43) has been implicated in the pathogenesis of human neurodegenerative diseases and exhibits hallmark neuropathology in amyotrophic lateral sclerosis (ALS). Here, we explore its tractability as a plasma bi
Externí odkaz:
https://doaj.org/article/a0db3bccec97456caa51182a2870d211
Autor:
Alejandro Acien, Narghes Calcagno, Katherine M. Burke, Ijah Mondesire-Crump, Ashley A. Holmes, Sri Mruthik, Ben Goldy, Janina E. Syrotenko, Zoe Scheier, Amrita Iyer, Alison Clark, Mackenzie Keegan, Yoshiteru Ushirogawa, Atsushi Kato, Taku Yasuda, Amir Lahav, Satoshi Iwasaki, Mark Pascarella, Stephen A. Johnson, Teresa Arroyo-Gallego, James D. Berry
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative condition leading to progressive muscle weakness, atrophy, and ultimately death. Traditional ALS clinical evaluations often depend on subjective metrics, making accurate
Externí odkaz:
https://doaj.org/article/2498bc03479647a985a2b9a0dfe827ac
Autor:
Marta Karas, Julia Olsen, Marcin Straczkiewicz, Stephen A. Johnson, Katherine M. Burke, Satoshi Iwasaki, Amir Lahav, Zoe A. Scheier, Alison P. Clark, Amrita S. Iyer, Emily Huang, James D. Berry, Jukka‐Pekka Onnela
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 6, Pp 1380-1392 (2024)
Abstract Background Passively collected smartphone sensor data provide an opportunity to study physical activity and mobility unobtrusively over long periods of time and may enable disease monitoring in people with amyotrophic lateral sclerosis (PALS
Externí odkaz:
https://doaj.org/article/f72db7bc3351444789ad6d6fc4cde97e
Autor:
Ruth Luthi-Carter, Sara Cappelli, Morgan Le Roux-Bourdieu, Noemie Tentillier, James P. Quinn, Tiziana Petrozziello, Lathika Gopalakrishnan, Purva Sethi, Himanshi Choudhary, Giorgia Bartolini, Elias Gebara, Cristiana Stuani, Laure Font, Jiyan An, Vanessa Ortega, Jessica Sage, Edina Kosa, Bianca A. Trombetta, Roberto Simeone, Tamara Seredenina, Tariq Afroz, James D. Berry, Steven E. Arnold, Becky C. Carlyle, Oskar Adolfsson, Ghazaleh Sadri-Vakili, Emanuele Buratti, Robert Bowser, Abdulbaki Agbas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/04bc4fed7dff4b25be434aa0fd9825ad
Autor:
Marcin Straczkiewicz, Marta Karas, Stephen A. Johnson, Katherine M. Burke, Zoe Scheier, Tim B. Royse, Narghes Calcagno, Alison Clark, Amrita Iyer, James D. Berry, Jukka-Pekka Onnela
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105036- (2024)
Summary: Background: Objective evaluation of people with amyotrophic lateral sclerosis (PALS) in free-living settings is challenging. The introduction of portable digital devices, such as wearables and smartphones, may improve quantifying disease pro
Externí odkaz:
https://doaj.org/article/6d1dfa302d2f4761bdf2eabbe9a51d1f
Autor:
Stephen A. Johnson, Marta Karas, Katherine M. Burke, Marcin Straczkiewicz, Zoe A. Scheier, Alison P. Clark, Satoshi Iwasaki, Amir Lahav, Amrita S. Iyer, Jukka-Pekka Onnela, James D. Berry
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-10 (2023)
Abstract Amyotrophic lateral sclerosis (ALS) therapeutic development has largely relied on staff-administered functional rating scales to determine treatment efficacy. We sought to determine if mobile applications (apps) and wearable devices can be u
Externí odkaz:
https://doaj.org/article/02887f47e22d43be9f4f4f7017ac6466
Autor:
Marziye Eshghi, Yana Yunusova, Kathryn P. Connaghan, Bridget J. Perry, Marc F. Maffei, James D. Berry, Lorne Zinman, Sanjay Kalra, Lawrence Korngut, Angela Genge, Annie Dionne, Jordan R. Green
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Although speech declines rapidly in some individuals with amyotrophic lateral sclerosis (ALS), longitudinal changes in speech have rarely been characterized. The study objectives were to model the rate of decline in speaking rate and speech
Externí odkaz:
https://doaj.org/article/d1d83f13de6d4055a49c73802aecdbd7
Autor:
Jonathan S. Katz, Jeffrey D. Rothstein, Merit E. Cudkowicz, Angela Genge, Björn Oskarsson, Avis B. Hains, Chen Chen, Joshua Galanter, Braydon L. Burgess, William Cho, Geoffrey A. Kerchner, Felix L. Yeh, Arundhati Sengupta Ghosh, Sravanthi Cheeti, Logan Brooks, Lee Honigberg, Jessica A. Couch, Michael E. Rothenberg, Flavia Brunstein, Khema R. Sharma, Leonard van denBerg, James D. Berry, Jonathan D. Glass
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 9, Iss 1, Pp 50-66 (2022)
Abstract Objective Dual leucine zipper kinase (DLK), which regulates the c‐Jun N‐terminal kinase pathway involved in axon degeneration and apoptosis following neuronal injury, is a potential therapeutic target in amyotrophic lateral sclerosis (AL
Externí odkaz:
https://doaj.org/article/fe4980573fc74660b0489437b3effc6d
Autor:
Yana Yunusova, Ashley Waito, Carolina Barnett Tapia, Anna Huynh, Rosemary Martino, Agessandro Abrahao, Gary L. Pattee, James D. Berry, Lorne Zinman, Jordan R. Green
Publikováno v:
Frontiers in Neurology, Vol 13 (2023)
PurposeEarly detection and tracking of bulbar dysfunction in amyotrophic lateral sclerosis (ALS) are critical for directing management of the disease. Existing physiological assessments of bulbar dysfunction are often inaccessible and cost-prohibitiv
Externí odkaz:
https://doaj.org/article/ed653f102b6c43b598aec04935874ea6
Autor:
Benjamin Rix Brooks, James D. Berry, Malgorzata Ciepielewska, Ying Liu, Gustavo Suarez Zambrano, Jeffrey Zhang, Melissa Hagan
Publikováno v:
EClinicalMedicine, Vol 52, Iss , Pp 101590- (2022)
Summary: Background: We aimed to evaluate overall survival in US patients with amyotrophic lateral sclerosis (ALS) treated with intravenous (IV) edaravone compared with those not treated with IV edaravone in a real-world setting. Methods: This explor
Externí odkaz:
https://doaj.org/article/b262c9a377a5482cac0b6d76743fb534