Zobrazeno 1 - 10
of 34
pro vyhledávání: '"James Coyne"'
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The creation of protective barriers around cells is of interest for a range of applications. Here, the authors report on the creation of DNA templated alginate-polylysine biomimetic cell walls for encapsulating and shielding cells, demonstrating prot
Externí odkaz:
https://doaj.org/article/f77e11608df148dda27fd68b08310812
Autor:
Roland Mergl, Nicole Koburger, Katherina Heinrichs, András Székely, Mónika Ditta Tóth, James Coyne, Sónia Quintão, Ella Arensman, Claire Coffey, Margaret Maxwell, Airi Värnik, Chantal van Audenhove, David McDaid, Marco Sarchiapone, Armin Schmidtke, Axel Genz, Ricardo Gusmão, Ulrich Hegerl
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0129062 (2015)
BackgroundIn Europe, men have lower rates of attempted suicide compared to women and at the same time a higher rate of completed suicides, indicating major gender differences in lethality of suicidal behaviour. The aim of this study was to analyse th
Externí odkaz:
https://doaj.org/article/393c2069394d408db47641846a25579b
Autor:
Ricardo Gusmão, Sónia Quintão, David McDaid, Ella Arensman, Chantal Van Audenhove, Claire Coffey, Airi Värnik, Peeter Värnik, James Coyne, Ulrich Hegerl
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66455 (2013)
Research concerning the association between use of antidepressants and incidence of suicide has yielded inconsistent results and is the subject of considerable controversy. The first aim is to describe trends in the use of antidepressants and rates o
Externí odkaz:
https://doaj.org/article/9fc117b91f6f4d79bc5d4fbd94d934c8
Publikováno v:
Angewandte Chemie. 132:11990-11995
An ability to promote therapeutic immune cells to recognize cancer cells is important for the success of cell-based cancer immunotherapy. We present a synthetic method for functionalizing the surface of natural killer (NK) cells with a supramolecular
Autor:
Ge Zhang, Xiaolong Zhang, Lidya Abune, James Coyne, Akiho Suzuki, Huizhen Jia, Na Xiong, Peng Shi, Yong Wang, Nan Zhao
Publikováno v:
ACS Appl Mater Interfaces
In situ injectable hydrogels hold great potential for in vivo applications such as drug delivery and regenerative medicine. However, it is challenging to ensure stable sequestration and sustained release of loaded biomolecules in these hydrogels. As
Publikováno v:
ACS Appl Mater Interfaces
Mesenchymal stem cells (MSCs) have a very low survival rate after in vivo delivery, which limits their great promise for treating human diseases. Various strategies have been studied to overcome this challenge. However, an overlooked but important po
Publikováno v:
J Allergy Clin Immunol
Psoriasis-associated suppression of the skin-specific chemokine/receptor CCL27/CCR10 axis leads to enhanced pathogenic IL-17A/IL-22-producing skin T cell activation and inflammation.
Publikováno v:
J Control Release
Hydrogels for biomedical applications such as controlled drug release are usually synthesized with the chemical or physical crosslinking of monomers or macromers. In this work, we used gelatin to prepare hydrogel nanoparticles and studied whether gel
Publikováno v:
ACS Biomaterials Science & Engineering. 3:3395-3403
Overexpression of proteins in the body can cause severe diseases and other physiological disturbances. The development of protein blockers and local delivery systems would offer opportunities for addressing the health problems caused by protein overe
Autor:
James Coyne, Yong Wang, Jinping Lai, Xuechen Shi, Nan Zhao, Yingwei Mao, Fengping Dong, Shihui Li
Publikováno v:
Chem. Sci.. 8:7306-7311
A variety of hydrogels have been synthesized for controlling the release of signaling molecules in applications such as drug delivery and regenerative medicine. However, it remains challenging to synthesize hydrogels with the ability to control the r