Zobrazeno 1 - 10
of 42
pro vyhledávání: '"James Claffey"'
Autor:
Siddappa A. Patil, Anthony Deally, Holger Weber, Brendan Gleeson, Matthias Tacke, Iduna Fichtner, James Claffey, Diana Behrens
Publikováno v:
Letters in Drug Design & Discovery. 8:302-307
The 4-diethylaminomethylbenzyl-substituted titanocene dichloride (Titanocene Y*), which is completely water- soluble and showed nanomolar activity against the human renal cancer cells CAKI-1, was tested in vitro in an antiangiogenesis assay against h
Publikováno v:
Applied Organometallic Chemistry. 24:675-679
Starting from the potential anticancer drug candidate Titanocene Y {bis-[(4-methoxybenzyl)cyclopentadienyl]titanium(IV) dichloride}, anion exchange experiments were performed using silver malonate (1a) or silver cyclobutane-1,1-malonate (1b) in order
Publikováno v:
Journal of Organometallic Chemistry. 695:2105-2117
Through the reaction of Super Hydride (LiBEt3H) with 6-phenyl-substituted fulvenes followed by transmetallation to TiCl4 ten novel benzyl-substituted titanocene dichloride derivatives were synthesised. 6(4-morpholinomethyl-phenyl) fulvene (6g) and (b
Autor:
Matthias Tacke, Siddappa A. Patil, Megan Hogan, Donal F. O'Shea, Helge Müller-Bunz, Brendan Gleeson, James Claffey, Anthony Deally
Publikováno v:
Polyhedron. 29:2445-2453
From the reaction of various 6-indolylfulvenes (1a−f) with Super Hydride (LiBEt3H), followed by transmetalation with titanium tetrachloride (TiCl4), six indolyl-substituted titanocenes, bis[(1-methylindol-2-yl)cyclopentadienyl]titanium(IV) dichlori
Autor:
Brendan Gleeson, James Claffey, Anthony Deally, Megan Hogan, Luis Miguel Menéndez Méndez, Helge Müller-Bunz, Siddappa Patil, Matthias Tacke
Publikováno v:
Inorganica Chimica Acta. 363:1831-1836
Autor:
Iduna Fichtner, Anthony Deally, Megan Hogan, Holger Weber, Maria Rivera Markelova, James Claffey, Brendan Gleeson, Matthias Tacke, Helge Müller-Bunz
Publikováno v:
Journal of Organometallic Chemistry. 695:1175-1181
The para-methoxybenzyl-substituted vanadocene dichloride (Vanadocene Y) (1) and its diselenocyanate (Selenocyanato-Vanadocene Y) (2) were tested in vitro in an anti-angiogenesis assay against human umbilical vein endothelial cells (HUVEC) delivering
Autor:
Helge Müller-Bunz, Matthias Tacke, Anthony Deally, Luis Miguel Menéndez Méndez, Brendan Gleeson, Siddappa A. Patil, Megan Hogan, James Claffey, Francesca Paradisi
Publikováno v:
European Journal of Inorganic Chemistry. 2010:1020-1031
p-Methoxybenzyl-substituted and benzyl-substituted N-heterocyclic carbene (NHC) [(3a-c) and (6a-c)] precursors were synthesised from the reaction of 1H-imidazole (1a), 4,5-dichloro-1H-imidazole (1b), and 1H-benzimidazole (1c) with p-methoxybenzyl bro
Autor:
Gerhard Hamilton, Matthias Tacke, Ulrike Olszewski, Patrick J. Bednarski, Megan Hogan, Robert Zeillinger, James Claffey
Publikováno v:
Investigational New Drugs. 29:607-614
Titanocenes constitute a class of metal-based anticancer agents that seem to display a mode of action distinct from that of platinum complexes and to be more tolerable with a differing spectrum of activity. In the present study, titanocene C (bis-(N,
Autor:
Siddappa A. Patil, Megan Hogan, Matthias Tacke, Helge Müller-Bunz, Denise Wallis, Anthony Deally, Luis Miguel Menéndez Méndez, Brendan Gleeson, James Claffey
Publikováno v:
European Journal of Inorganic Chemistry. 2009:2804-2810
From the reaction of 6-(2-fluoro-4-methoxyphenyl)fulvene (1a), 6-(3-fluoro-4-methoxyphenyl)fulvene (1b) and 6-[4-(trifluoromethoxy)phenyl]fulvene (1c) with LiBEt3H, lithiated cyclopentadienide intermediates (2a–c) were synthesised. These intermedia
Autor:
Brendan Gleeson, James Claffey, Megan Hogan, Helge Müller-Bunz, Denise Wallis, Matthias Tacke
Publikováno v:
Journal of Organometallic Chemistry. 694:1369-1374