Zobrazeno 1 - 10
of 127
pro vyhledávání: '"James Chambers"'
Autor:
Nathaniel Grabill, MD, Mena Louis, DO, Mariah Cawthon, MD, Joseph Conway, MD, James Chambers, MD
Publikováno v:
Radiology Case Reports, Vol 19, Iss 11, Pp 4824-4831 (2024)
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract, frequently characterized by mutations in the KIT or PDGFRA genes. This case report details the complex clinical course of a 71-year-old f
Externí odkaz:
https://doaj.org/article/4a0c6945dac640c99e1d1f48987ac52d
Autor:
Nathaniel Grabill, MD, Mena Louis, DO, Mariah Cawthon, MD, Claudia Gherasim, MD, James Chambers, MD
Publikováno v:
Radiology Case Reports, Vol 19, Iss 12, Pp 6016-6026 (2024)
Adenosquamous carcinoma of the pancreas (ASCP) is a rare and aggressive variant of pancreatic cancer, characterized by both adenocarcinoma and squamous cell carcinoma components. It presents significant diagnostic and therapeutic challenges due to it
Externí odkaz:
https://doaj.org/article/784af63923114cdf8e71bd5db5955890
Publikováno v:
Stress, Vol 27, Iss 1 (2024)
Chronic stress leads to hypofunction of the medial prefrontal cortex (mPFC), mechanisms of which remain to be determined. Enhanced activation of GABAergic of parvalbumin (PV) expressing interneurons (INs) is thought to play a role in stress-induced p
Externí odkaz:
https://doaj.org/article/744a67ef492c41d3b85a20eb793e09ea
Autor:
Keitaro YAMANOUCHI, Shizuka KATO, Yukie TANAKA, Masanari IKEDA, Yukina OSHIMO, Takanori SHIGA, Kei HATAMOTO, James CHAMBERS, Takuya IMAMURA, Ryuji HIRAMATSU, Kazuyuki UCHIDA, Fuko MATSUDA, Takashi MATSUWAKI, Tetsuya KOHSAKA
Publikováno v:
The Journal of Reproduction and Development, Vol 70, Iss 2, Pp 55-64 (2024)
The mammalian X chromosome exhibits enrichment in genes associated with germ cell development. Previously, we generated a rat model of Becker muscular dystrophy (BMD) characterized by an in-frame mutation in the dystrophin gene, situated on the X chr
Externí odkaz:
https://doaj.org/article/ecc08a81b4cf491cb44a10573b2b3d4f
Autor:
Christopher Marang, Brent Scott, James Chambers, Laura K. Gunther, Christopher M. Yengo, Edward P. Debold
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Myosin Va is the molecular motor that drives intracellular vesicular transport, powered by the transduction of chemical energy from ATP into mechanical work. The coupling of the powerstroke and phosphate (Pi) release is key to understanding
Externí odkaz:
https://doaj.org/article/b973fbcda2984834bd41b7df0d6f4025
Autor:
Keitaro Yamanouchi, Yukie Tanaka, Masanari Ikeda, Shizuka Kato, Ryosuke Okino, Hiroki Nishi, Fumihiko Hakuno, Shin-Ichiro Takahashi, James Chambers, Takashi Matsuwaki, Kazuyuki Uchida
Publikováno v:
Skeletal Muscle, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Background Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by a complete lack of dystrophin, which stabilizes the plasma membrane of myofibers. The orofacial function is affected in an advanced stage of DMD and this of
Externí odkaz:
https://doaj.org/article/aeae3a048a30439680dbbe41dd4509b4
Autor:
Howard L. Kaufman, Michael B. Atkins, Prasun Subedi, James Wu, James Chambers, T. Joseph Mattingly, Jonathan D. Campbell, Jeff Allen, Andrea E. Ferris, Richard L. Schilsky, Daniel Danielson, J. Leonard Lichtenfeld, Linda House, Wendy K. D. Selig
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract The rapid development of immuno-oncology (I-O) therapies for multiple types of cancer has transformed the cancer treatment landscape and brightened the long-term outlook for many patients with advanced cancer. Responding to ongoing efforts t
Externí odkaz:
https://doaj.org/article/32134812e74f40ba9ecc09ba55ae0b31
Autor:
Sho Yoshimoto, Daiki Kato, Satoshi Kamoto, Kie Yamamoto, Masaya Tsuboi, Masahiro Shinada, Namiko Ikeda, Yuiko Tanaka, Ryohei Yoshitake, Shotaro Eto, Kohei Saeki, James Chambers, Ryohei Kinoshita, Kazuyuki Uchida, Ryohei Nishimura, Takayuki Nakagawa
Publikováno v:
Heliyon, Vol 5, Iss 7, Pp e02004- (2019)
The human epidermal growth factor receptor 2 (HER2) is expressed in various human cancers including thyroid cancers (TC) and is used as a diagnostic marker and therapeutic target. Canine TC (cTC), the most common endocrine malignancy in dogs, shows a
Externí odkaz:
https://doaj.org/article/c826c08557774a318c223e2cf03be560
Autor:
Shotaro Eto, Kohei Saeki, Ryohei Yoshitake, Sho Yoshimoto, Masahiro Shinada, Namiko Ikeda, Satoshi Kamoto, Yuiko Tanaka, Daiki Kato, Shingo Maeda, Masaya Tsuboi, James Chambers, Kazuyuki Uchida, Ryohei Nishimura, Takayuki Nakagawa
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218382 (2019)
Canine urothelial carcinoma (cUC) is the most common tumor of the lower urinary tract in dogs. Although chemotherapy and radical surgery have improved the overall survival, most dogs with cUC succumb to metastasis or recurrence. Therefore, the develo
Externí odkaz:
https://doaj.org/article/74e82af3ac9642e29d29432edaf683fa
Autor:
Satoshi Kamoto, Masahiro Shinada, Daiki Kato, Sho Yoshimoto, Namiko Ikeda, Masaya Tsuboi, Ryohei Yoshitake, Shotaro Eto, Yuko Hashimoto, Yosuke Takahashi, James Chambers, Kazuyuki Uchida, Mika K. Kaneko, Naoki Fujita, Ryohei Nishimura, Yukinari Kato, Takayuki Nakagawa
Publikováno v:
Cells, Vol 9, Iss 11, p 2529 (2020)
Podoplanin (PDPN), a small transmembrane mucin-like glycoprotein, is ectopically expressed on tumor cells. PDPN is known to be linked with several aspects of tumor malignancies in certain types of human and canine tumors. Therefore, it is considered
Externí odkaz:
https://doaj.org/article/3eb3786967f4411aaccfb5688edd0290