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pro vyhledávání: '"James Cavalcoli"'
Autor:
Justin R Hassler, Donalyn L Scheuner, Shiyu Wang, Jaeseok Han, Vamsi K Kodali, Philip Li, Julie Nguyen, Jenny S George, Cory Davis, Shengyang P Wu, Yongsheng Bai, Maureen Sartor, James Cavalcoli, Harmeet Malhi, Gregory Baudouin, Yaoyang Zhang, John R Yates, Pamela Itkin-Ansari, Niels Volkmann, Randal J Kaufman
Publikováno v:
PLoS Biology, Vol 13, Iss 10, p e1002277 (2015)
Although glucose uniquely stimulates proinsulin biosynthesis in β cells, surprisingly little is known of the underlying mechanism(s). Here, we demonstrate that glucose activates the unfolded protein response transducer inositol-requiring enzyme 1 al
Externí odkaz:
https://doaj.org/article/10407ba79b154e0899dd1b1e445895a1