Zobrazeno 1 - 4
of 4
pro vyhledávání: '"James C.A. Hopkins"'
Autor:
Janusz Pachucki, Suzy D. Carvalho, P. Reed Larsen, Frederic E. Wondisford, E. Dale Abel, Helen C. Kaulbach, Helen Tu, Robin Peeters, James C.A. Hopkins, Joanne S. Ingwall
Publikováno v:
Endocrinology. 142:13-20
Type 2 iodothyronine deiodinase (D(2)) catalyzes intracellular 3, 5, 3' triiodothyronine (T(3)) production from thyroxine (T(4)), and its messenger RNA mRNA is highly expressed in human, but not rodent, myocardium. The goal of this study was to ident
Publikováno v:
Journal of Biological Chemistry. 275:19742-19746
Creatine kinase (CK) exists as a family of isoenzymes in excitable tissue. We studied isolated perfused hearts from mice lacking genes for either the main muscle isoform of CK (M-CK) or both M-CK and the main mitochondrial isoform (Mt-CK) to determin
Autor:
Mary Ellen Boers, Ed Hadro, Barbara B. Kahn, James C.A. Hopkins, E. Dale Abel, Bradford B. Lowell, Joanne S. Ingwall, Helen C. Kaulbach, Rong Tian, William C. Quist, Timo Minnemann, Corinna Oberste-Berghaus, Thomas Doetschman, John J. Duffy
Publikováno v:
Journal of Clinical Investigation. 104:1703-1714
Glucose enters the heart via GLUT1 and GLUT4 glucose transporters. GLUT4-deficient mice develop striking cardiac hypertrophy and die prematurely. Whether their cardiac changes are caused primarily by GLUT4 deficiency in cardiomyocytes or by metabolic
Autor:
Matthias Spindler, James C.A. Hopkins, S. A. Camacho, Rong Tian, Jessica M. Halow, Michael E. Christe, Joanne S. Ingwall
Publikováno v:
The Journal of clinical investigation. 99(4)
Sarcomere relaxation depends on dissociation of actin and myosin, which is regulated by a number of factors, including intracellular [MgATP] as well as MgATP hydrolysis products [MgADP] and inorganic phosphate [Pi], pHi, and cytosolic calcium concent