Zobrazeno 1 - 10
of 383
pro vyhledávání: '"James C. Phillips"'
Autor:
Caroline Jay, Robert Haines, Daniel S. Katz, Jeffrey C. Carver, Sandra Gesing, Steven R. Brandt, James Howison, Anshu Dubey, James C. Phillips, Hui Wan, Matthew J. Turk
Publikováno v:
F1000Research, Vol 9 (2020)
Background: Software is now ubiquitous within research. In addition to the general challenges common to all software development projects, research software must also represent, manipulate, and provide data for complex theoretical constructs. Ensurin
Externí odkaz:
https://doaj.org/article/3f43c6626dee400495888507ab2503d3
Autor:
Marcelo A. Moret, T. M. Rocha Filho, Carson C. Chow, Antônio Cordeiro, José F. F. Mendes, Fulvio A. Scorza, A.-C.G. Almeida, James C. Phillips
Publikováno v:
Chaos, Solitons, and Fractals
We introduce a compartmental model SEIAHRV (Susceptible, Exposed, Infected, Asymptomatic, Hospitalized, Recovered, Vaccinated) with age structure for the spread of the SARAS-CoV virus. In order to model current different vaccines we use compartments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf5181d0ec94d94958ca8308a264af7e
http://hdl.handle.net/10773/36658
http://hdl.handle.net/10773/36658
Autor:
Fulvio A. Scorza, Antônio Cordeiro, James C. Phillips, Antonio-Carlos G. de Almeida, Carson C. Chow, Tarcísio M. Rocha Filho, Marcelo A. Moret, José F. F. Mendes
Publikováno v:
Research Square
article-version (status) pre
article-version (number) 2
article-version (status) pre
article-version (number) 2
We introduce a compartmental model with age structure to study the dynamics of the SARS-COV−2 pandemic. The contagion matrix in the model is given by the product of a probability per contact with a contact matrix explicitly taking into account the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085338d9e471222862f9d741acd31be5
https://pubmed.ncbi.nlm.nih.gov/34268503
https://pubmed.ncbi.nlm.nih.gov/34268503
Publikováno v:
Physica A: Statistical Mechanics and its Applications. 514:573-579
Granted that neural networks are nature’s most amazing invention, what is in second place? One candidate is the human eye, and specifically its transparent lens. Here we use the evolution of the lens’ dominant proteins to quantify subtle improvem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc9cc87add5a2c274bbe4a6febcd0490
https://doi.org/10.1016/j.physa.2018.09.128
https://doi.org/10.1016/j.physa.2018.09.128
Publikováno v:
Physica A: Statistical Mechanics and its Applications. 598:127318
The novel coronavirus SARS CoV-2 responsible for the COVID-19 pandemic and SARS CoV-1 responsible for the SARS epidemic of 2002-2003 share an ancestor yet evolved to have much different transmissibility and global impact1. A previously developed ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f08f7fc9299e04d4980fc03a89209a90
https://doi.org/10.1016/j.physa.2022.127318
https://doi.org/10.1016/j.physa.2022.127318
Autor:
Shantenu Jha, Julio D.C. Maia, Emilia P. Barros, Matteo Turilli, Abraham C. Stern, John E. Stone, Syma Khalid, Abigail C. Dommer, Surl-Hee Ahn, Lillian T. Chong, Austin Clyde, Zied Gaieb, Heng Ma, Thorsten Kurth, Lorenzo Casalino, John McCalpin, David J. Hardy, Tom Gibbs, Rommie E. Amaro, Anthony T. Bogetti, Arvind Ramanathan, Carlos Simmerling, Anda Trifan, Hyungro Lee, James C. Phillips, Mahidhar Tatineni, Alexander Brace, Lei Huang, Terra Sztain
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
The International Journal of High Performance Computing Applications
article-version (status) pre
article-version (number) 1
The International Journal of High Performance Computing Applications
We develop a generalizable AI-driven workflow that leverages heterogeneous HPC resources to explore the time-dependent dynamics of molecular systems. We use this workflow to investigate the mechanisms of infectivity of the SARS-CoV-2 spike protein, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e2b162bafcb111788c5f8efca47cfc6
http://europepmc.org/articles/PMC7685317
http://europepmc.org/articles/PMC7685317
Autor:
James Howison, Hui Wan, Matthew J. Turk, Anshu Dubey, Daniel S. Katz, Caroline Jay, Robert Haines, James C. Phillips, Sandra Gesing, Steven R. Brandt, Jeffrey C. Carver
Publikováno v:
F1000Research
Background: Software is now ubiquitous within research. In addition to the general challenges common to all software development projects, research software must also represent, manipulate, and provide data for complex theoretical constructs. Ensurin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771c252ac834cbe88e0812ed98f255e0
https://pubmed.ncbi.nlm.nih.gov/33214878
https://pubmed.ncbi.nlm.nih.gov/33214878
Autor:
Ryan McGreevy, Julio D.C. Maia, David J. Hardy, Giacomo Fiorin, Zaida Luthey-Schulten, Aleksei Aksimentiev, Emad Tajkhorshid, James C. Phillips, John E. Stone, Yi Wang, Benoît Roux, João V. Ribeiro, Wei Jiang, Christophe Chipot, Robert D. Skeel, Ronak Buch, Jérôme Hénin, Abhishek Singharoy, Rafael C. Bernardi, Brian K. Radak, Marcelo C. R. Melo, Klaus Schulten, Laxmikant V. Kale
Publikováno v:
Journal of Chemical Physics
Journal of Chemical Physics, American Institute of Physics, 2020, 153 (4), pp.044130. ⟨10.1063/5.0014475⟩
J Chem Phys
Journal of Chemical Physics, American Institute of Physics, 2020, 153 (4), pp.044130. ⟨10.1063/5.0014475⟩
J Chem Phys
International audience; NAMD is a molecular dynamics program designed for high-performance simulations of very large biological objects on central processing unit (CPU)-and graphics processing unit (GPU)-based architectures. NAMD offers scalable perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ba6402af2a0f87d67e384c19fd767f
https://hal.archives-ouvertes.fr/hal-03007668
https://hal.archives-ouvertes.fr/hal-03007668
Autor:
James C. Phillips
Publikováno v:
Proc Natl Acad Sci U S A
Cytoskeletons are self-organized networks based on polymerized proteins: actin, tubulin, and driven by motor proteins, such as myosin, kinesin, and dynein. Their positive Darwinian evolution enables them to approach optimized functionality (self-orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02cfe72284214693fe288686fa3e94e3
https://europepmc.org/articles/PMC7149232/
https://europepmc.org/articles/PMC7149232/
Autor:
James C. Phillips
Publikováno v:
Physica a
CoV2019 has evolved to be much more dangerous than CoV2003. Experiments suggest that structural rearrangements dramatically enhance CoV2019 activity. We identify a new first stage of infection which precedes structural rearrangements by using biomole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::969ccb070bffe3d1960455c9cfa20b6f