Zobrazeno 1 - 10
of 126
pro vyhledávání: '"James C. Parker"'
Autor:
Masahiro Hashizume, Marc Mouner, Joshua M. Chouteau, Olena M. Gorodnya, Mykhaylo V. Ruchko, Glenn L. Wilson, Mark N. Gillespie, James C. Parker
Publikováno v:
Pharmaceuticals, Vol 7, Iss 8, Pp 894-912 (2014)
The mitochondrial targeted DNA repair enzyme, 8-oxoguanine DNA glycosylase 1, was previously reported to protect against mitochondrial DNA (mtDNA) damage and ventilator induced lung injury (VILI). In the present study we determined whether mitochondr
Externí odkaz:
https://doaj.org/article/aedabb7b3ee04d84a1a128d171da1058
Autor:
Yuting Wang, Héctor Gil-Marín, Peter M. Frinchaboy, Rossana Ruggeri, Andreu Font-Ribera, Jean-Paul Kneib, Christophe Balland, Mark A. Klaene, Jiamin Hou, Graziano Rossi, Abhishek Prakash, Adam D. Myers, Richard Neveux, Kathleen Grabowski, Chia-Hsun Chuang, M. C. Cousinou, Andrea Muñoz-Gutiérrez, Matthew M. Pieri, Patrick Petitjean, C. Yeche, Adam S. Bolton, Hui Kong, Pauline Zarrouk, Johan Comparat, Thomas Etourneau, Audrey Oravetz, Ashley J. Ross, Dmitry Bizyaev, Romain Paviot, Mehdi Rezaie, Amélie Tamone, James C. Parker, Gong-Bo Zhao, Faizan G. Mohammad, Santiago Avila, Jeffrey A. Newman, F. Javier Sánchez, Joel R. Brownstein, Kyle S. Dawson, Sylvain de la Torre, Peter Doohyun Choi, Daniel Long, Julian E. Bautista, Sicheng Lin, Alex Smith, José R. Sánchez-Gallego, Andrei Variu, Seshadri Nadathur, Daniel Oravetz, Stephanie Escoffier, Eva Maria Mueller, Jeongin Moon, Etienne Burtin, Mariana Vargas-Magaña, Julianna Stermer, Axel de la Macorra, Matthew A. Bershady, Hee-Jong Seo, Anand Raichoor, Paul Martini, Solène Chabanier, Ignasi Pérez-Ràfols, J. Rich, Anne-Marie Weijmans, Ariel G. Sánchez, Benjamin A. Weaver, Conor Sayres, Violeta Gonzalez-Perez, Kaike Pan, Will J. Percival, Corentin Ravoux, Adam J. Hawken, Jeremy L. Tinker, Zheng Zheng, Anže Slosar, Nathalie Palanque-Delabrouille, Cheng Zhao, Alma X. Gonzalez-Morales, Andrei Cuceu, P. Noterdaeme, V. Ruhlmann-Kleider, Arnaud de Mattia, Julien Guy, James Farr, Jo Bovy, Brad W. Lyke, Marie Aubert, Michael J. Chapman, Jean Marc Le Goff, Hélion du Mas des Bourboux, S. Fromenteau, Jonathan Brinkmann, Shadab Alam, Rita Tojeiro, Arman Shafieloo, Michael R. Blanton, Donald P. Schneider, Karen L. Masters, Victoria de Sainte Agathe
Publikováno v:
Physical Review D, vol 103, iss 8
Phys.Rev.D
Phys.Rev.D, 2021, 103 (8), pp.083533. ⟨10.1103/PhysRevD.103.083533⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biblos-e Archivo. Repositorio Institucional de la UAM
Phys.Rev.D
Phys.Rev.D, 2021, 103 (8), pp.083533. ⟨10.1103/PhysRevD.103.083533⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname
Biblos-e Archivo. Repositorio Institucional de la UAM
Shadab, Alam et al.
We present the cosmological implications from final measurements of clustering using galaxies, quasars, and Lyα forests from the completed Sloan Digital Sky Survey (SDSS) lineage of experiments in large-scale structure. Thes
We present the cosmological implications from final measurements of clustering using galaxies, quasars, and Lyα forests from the completed Sloan Digital Sky Survey (SDSS) lineage of experiments in large-scale structure. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b1750bd206eeaf1ef550e37a6ec51c
https://escholarship.org/uc/item/8t474214
https://escholarship.org/uc/item/8t474214
Autor:
Todd E. Golde, Marshall S. Goodwin, Jeffery W. Kelly, Yona Levites, Kristopher L. Nazor, Michael R. Sierks, James C. Parker, Nicholas J. Schork, Stuart A. Lipton, Titas Grabauskas, Dorit Trudler, Rajesh Ambasudhan, Michael Karin, Abdullah Sultan, Zhenyu Zhong, Yvonne S. Eisele, Nima Dolatabadi
Publikováno v:
Proc Natl Acad Sci U S A
Parkinson’s disease is characterized by accumulation of α-synuclein (αSyn). Release of oligomeric/fibrillar αSyn from damaged neurons may potentiate neuronal death in part via microglial activation. Heretofore, it remained unknown if oligomeric/
Autor:
Bakker C, Rajesh Ambasudhan, Melissa Luevanos, Pawel Stankiewicz, Abdullah Sultan, Daniel H. Geschwind, Nima Dolatabadi, Riki Kawaguchi, Nicholas J. Schork, Maria Talantova, Michael G. Rosenfeld, Yongwook Choi, Teranaka M, Ivan Garcia-Bassets, Agnes P. Chan, Grabauskas T, James C. Parker, Kozbial P, Swagata Ghatak, Stuart A. Lipton, Shing Fai Chan, Kevin M. Lopez, Nobuki Nakanishi, Noveral Sm, Dorit Trudler
MEF2C has been shown to be a critical transcription factor for neurodevelopment, whose loss-of-function mutation in humans results in MEF2C haploinsufficiency syndrome (MHS), a severe form of autism spectrum disorder (ASD)/intellectual disability (ID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d399ffbf3ff7ea7c0988109d1c98e31c
https://doi.org/10.1101/2020.11.19.387639
https://doi.org/10.1101/2020.11.19.387639
Autor:
Edmond Chaussidon, Ignasi Pérez-Ràfols, Hee-Jong Seo, Solène Chabanier, Will J. Percival, Brad W. Lyke, Graziano Rossi, Nathalie Palanque-Delabrouille, Victoria de Sainte Agathe, Matthew M. Pieri, M. Vivek, Samantha Youles, Jean Marc Le Goff, Thomas Etourneau, James Rich, Patrick Petitjean, Anže Slosar, James C. Parker, Christophe Yèche, Julian E. Bautista, James Farr, Eva Maria Mueller, Kyle S. Dawson, Andrea Muñoz Gutiérrez, Andreu Font-Ribera, Jonathan Brinkmann, Alma X. Gonzalez-Morales, Andrei Cuceu, Julianna Stermer, Corentin Ravoux, Adam D. Myers, Hélion du Mas des Bourboux, Julien Guy, Axel de la Macorra, Joel R. Brownstein, Christophe Balland, Christian Nitschelm, Michael Blomqvist, Donald P. Schneider
Publikováno v:
Astrophys.J.
Astrophys.J., 2020, 901 (2), pp.153. ⟨10.3847/1538-4357/abb085⟩
The Astrophysical Journal
Astrophys.J., 2020, 901 (2), pp.153. ⟨10.3847/1538-4357/abb085⟩
The Astrophysical Journal
We present a measurement of baryonic acoustic oscillations (BAO) from Lyman-$\alpha$ (Ly$\alpha$) absorption and quasars at an effective redshift $z=2.33$ using the complete extended Baryonic Oscillation Spectroscopic Survey (eBOSS). The sixteenth an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6adf639f45c7a698916791d49e08fdd
https://hal.archives-ouvertes.fr/hal-02927703
https://hal.archives-ouvertes.fr/hal-02927703
Autor:
James C. Parker
Publikováno v:
Journal of lung health and diseases
Although reduced tidal volumes have improved patient survival during ventilation for acute lung injury, further improvements will require pharmacologic interventions of the cellular pathways for inflammation and injury. We previously reported that pr
Autor:
Walid Soussou, Stuart A. Lipton, Scott R. McKercher, Sara Sanz-Blasco, Nima Dolatabadi, Mohd Waseem Akhtar, Rajesh Ambasudhan, Michelle S. Lee, James C. Parker, Tomohiro Nakamura, Kevin Chon
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature communications, vol 7, iss 1
Nature Communications
Nature communications, vol 7, iss 1
Nature Communications
Metabolic syndrome (MetS) and Type 2 diabetes mellitus (T2DM) increase risk for Alzheimer's disease (AD). The molecular mechanism for this association remains poorly defined. Here we report in human and rodent tissues that elevated glucose, as found
Autor:
Timothy Holland, Abdullah Sultan, Scott R. McKercher, Rajesh Ambasudhan, Eliezer Masliah, Yuqiang Wang, Alexey V. Terskikh, Vivek Swarup, Huaxi Xu, Xiayu Huang, Mohd Waseem Akhtar, Daniel H. Geschwind, James C. Parker, Scott D. Ryan, Amanda J. Roberts, Shichun Tu, Rosa Maria Escorihuela, Xiaofei Zhang, Nobuki Nakanishi, Neha Bansal, Alejandro Amador-Arjona, Stuart A. Lipton, Shing Fai Chan, Li Yan, Kevin M. Lopez, Robert A. Rissman, Jeffrey D. Zaremba, Daniel R. Holohan
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Tu, Shichun; Akhtar, Mohd Waseem; Escorihuela, Rosa Maria; Amador-Arjona, Alejandro; Swarup, Vivek; Parker, James; et al.(2017). NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism.. Nature communications, 8(1), 1488. doi: 10.1038/s41467-017-01563-8. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5127z2zd
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Tu, Shichun; Akhtar, Mohd Waseem; Escorihuela, Rosa Maria; Amador-Arjona, Alejandro; Swarup, Vivek; Parker, James; et al.(2017). NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism.. Nature communications, 8(1), 1488. doi: 10.1038/s41467-017-01563-8. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5127z2zd
Transcription factor MEF2C regulates multiple genes linked to autism spectrum disorder (ASD), and human MEF2C haploinsufficiency results in ASD, intellectual disability, and epilepsy. However, molecular mechanisms underlying MEF2C haploinsufficiency
Autor:
Eliezer Masliah, Woong Sun, Hyun Jung Kim, Janghwan Kim, Sofiyan Saleem, Scott R. McKercher, Sara Sanz-Blasco, Xiao-Jing Wang, Rajesh Ambasudhan, Saiyong Zhu, Mingliang Zhang, Sheng Ding, Jeffrey D. Zaremba, Yu Zhang, Stuart A. Lipton, Han Seop Kim, Timothy Laurent, James C. Parker, Yee Sook Cho, Maria Talantova
Publikováno v:
Cell Research. 24:126-129
Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells
Autor:
Tomohiro Nakamura, Nobuki Nakanishi, James C. Parker, Nima Dolatabadi, Eliezer Masliah, Rajesh Ambasudhan, John R. Yates, Abdullah Sultan, Stuart A. Lipton, Carmen R. Sunico, Xuemei Han, Bing Shan
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 47
Significance S -nitrosylation, addition of an NO group to a cysteine thiol, can regulate protein activity. Aberrant protein S -nitrosylation, however, can disrupt normal enzyme function, as is the case for S -nitrosylated peroxiredoxin (SNO-Prx), whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92cc2ff1efaa512b65bac5acf8e75cb5
https://escholarship.org/uc/item/53h1q3qq
https://escholarship.org/uc/item/53h1q3qq