Zobrazeno 1 - 10
of 10
pro vyhledávání: '"James C. Muir"'
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2243-2250
A concise total synthesis of (+)-curacin A, a potent antimitotic agent isolated from the cyanobacterium Lyngbya majuscula, is described. The synthesis features a new strategy to the 2-cyclopropyl-4-alkenyl substituted thiazoline unit in the natural p
Publikováno v:
Tetrahedron Letters. 39:2861-2864
A total synthesis of (+)-curacin A 1 which features a facile and selective thioacylation of the polyene amino-alcohol 2 with the benzotriazole-derived cyclopropyl thioamide 3, leading to 15, as a key step is described.
Autor:
James C. Muir
Publikováno v:
Synthesis. 1998:613-618
Publikováno v:
ChemInform. 43
Enolates of N-substituted amino esters (I) and (III) undergo intramolecular cyclization reactions to afford (syn)-aza-anions that undergo 4-exo-trig cyclization onto their ester carbonyl group to afford cyclic β-lactams (II) and (IV) in high diaster
Publikováno v:
Organic letters. 13(23)
Enolates of chiral N-(α-methyl-p-methoxybenzyl)-ω-imino-esters undergo intramolecular cyclization reactions to afford (syn)-aza-anions of β-amino esters in high dr that cyclize to afford N-(α-methyl-p-methoxybenzyl)-β-lactams that can be readily
Publikováno v:
ChemInform. 29
A total synthesis of (+)-curacin A 1 which features a facile and selective thioacylation of the polyene amino-alcohol 2 with the benzotriazole-derived cyclopropyl thioamide 3, leading to 15, as a key step is described.
Publikováno v:
ChemInform. 29
Autor:
Charles L. Ianne, James C. Muir
Publikováno v:
American Journal of Obstetrics and Gynecology. 38:448-457
After some seemingly unnecessary tuberculosis deaths following pregnancy, tuberculin tests, with x-rays of the reactors, were added to our routine procedure for the examination of prenatals. Between June 1 1936, and June 1 1938, 805 women in the so-c
Autor:
James C. Muir
Publikováno v:
American journal of obstetrics and gynecology. 56(4)
I T IS generally accepted, and most textbooks recommend, that a retained placenta be removed surgically or manually. It is also generally believed that a placenta accreta or increta must be treated by hysterectomy. Greenhill, in the ninth edition of
Autor:
James C. Muir
Publikováno v:
American Journal of Obstetrics and Gynecology. 83:134