A paradigm for virus-host coevolution: sequential counter-adaptations between endogenous and exogenous retroviruses.

Autor: Frederick Arnaud, Marco Caporale, Mariana Varela, Roman Biek, Bernardo Chessa, Alberto Alberti, Matthew Golder, Manuela Mura, Ya-Ping Zhang, Li Yu, Filipe Pereira, James C Demartini, Kreg Leymaster, Thomas E Spencer, Massimo Palmarini

Publikováno v: PLoS Pathogens, Vol 3, Iss 11, p e170 (2007)

Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections of the host germline transmitted vertically from generation to generation. It is hypothesized that some ERVs are used by the host as restriction factors to block the infecti

Externí odkaz: https://doaj.org/article/1f5ec5efef904ddbb9e383f439f7aa89

Multiclonal pattern of Jaagsiekte sheep retrovirus integration sites in ovine pulmonary adenocarcinoma

Autor: Christina Cousens, James C. DeMartini, Jeanette V. Bishop, J. Michael Sharp, Adrian Philbey, Clare A. Gill

Publikováno v: Virus Research. 117:254-263

Insertional mutagenesis and envelope (Env)-mediated oncogenesis are hypothesized mechanisms by which Jaagsiekte sheep retrovirus (JSRV) causes ovine pulmonary adenocarcinoma (OPA). Twenty-eight JSRV integration sites in lung tumors (LTs) from four sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7023fab3404819e6b02e8f3eaf9bd948
https://doi.org/10.1016/j.virusres.2005.10.020

Analysis of Integration Sites of Jaagsiekte Sheep Retrovirus in Ovine Pulmonary Adenocarcinoma

Autor: Jonathan O. Carlson, James C. DeMartini, Christina Cousens, J. Michael Sharp, Adrian Philbey, Jeanette V. Bishop, Clare A. Gill, Massimo Palmarini

Publikováno v: Cousens, C, Bishop, J V, Philbey, A W, Gill, C A, Palmarini, M, Carlson, J O, DeMartini, J C & Sharp, J M 2004, ' Analysis of integration sites of Jaagsiekte sheep retrovirus in ovine pulmonary adenocarcinoma ', Journal of Virology, vol. 78, no. 16, pp. 8506-12 . https://doi.org/10.1128/JVI.78.16.8506-8512.2004

Ovine pulmonary adenocarcinoma (OPA) is an infectious lung tumor of sheep caused by Jaagsiekte sheep retrovirus (JSRV). To test the hypothesis that JSRV insertional mutagenesis is involved in the oncogenesis of OPA, we cloned and characterized 70 ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a664e8eb666e5e9c944cedf69ec102b
https://doi.org/10.1128/jvi.78.16.8506-8512.2004

Alveolar Type II Cells Expressing Jaagsiekte Sheep Retrovirus Capsid Protein and Surfactant Proteins Are the Predominant Neoplastic Cell Type in Ovine Pulmonary Adenocarcinoma

Autor: J. A. Platt, N. Kraipowich, James C. DeMartini, F. A. Villafane

Publikováno v: Veterinary Pathology. 39:341-352

Ovine pulmonary adenocarcinoma is caused by jaagsiekte sheep retrovirus. To gain insight into the histogenesis and viral pathogenesis of this neoplasm, the tumor cell phenotypes and differentiation state were correlated with the distribution of jaags

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703f533900b546facfd39cc9d0b9c891
https://doi.org/10.1354/vp.39-3-341

Malignant Catarrhal Fever: Polymerase Chain Reaction Survey for Ovine Herpesvirus 2 and Other Persistent Herpesvirus and Retrovirus Infections of Dairy Cattle and Bison

Autor: R. Page Dinsmore, James K. Collins, Tracy L. Vermedahl, Robert J. Callan, Christa Bruns, James C. DeMartini, Michael T. Jessen, Patricia C. Schultheiss, Gwen M. Anderson, Anita L. Schiebel

Publikováno v: Journal of Veterinary Diagnostic Investigation. 12:406-411

Using a polymerase chain reaction (PCR) test for sequences of ovine herpesvirus 2 (OHV2), this virus was shown to be significantly associated with sheep-associated malignant catarrhal fever (SA-MCF) in terminal cases of disease in 34 cattle and 53 bi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0718417b80eba5eab2f5ac168c23c02
https://doi.org/10.1177/104063870001200503