Zobrazeno 1 - 10
of 371
pro vyhledávání: '"James C Barton"'
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0302817 (2024)
BackgroundIgG subclass levels in hemochromatosis are incompletely characterized.MethodsWe characterized IgG subclass levels of referred hemochromatosis probands with HFE p.C282Y/p.C282Y (rs1800562) and human leukocyte antigen (HLA)-A and -B typing/ha
Externí odkaz:
https://doaj.org/article/d8ebbce8a8a94d2aaf4362d02113dee1
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0271973 (2022)
BackgroundScreening program participants with iron overload (IO) phenotypes without HFE p.C282Y/p.C282Y are incompletely characterized.MethodsWe studied white participants who had IO phenotypes without p.C282Y/p.C282Y in post-screening clinical exami
Externí odkaz:
https://doaj.org/article/ceefd17538ff4e23b057d2394ed9c416
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261690 (2021)
BackgroundIn hemochromatosis, causes of abdominal pain and its associations with cirrhosis are poorly understood.MethodsWe retrospectively compared characteristics of referred hemochromatosis probands with HFE p.C282Y homozygosity with/without biopsy
Externí odkaz:
https://doaj.org/article/702bf71fa79342d5b813cfee7099591c
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240522 (2020)
BackgroundAdults with IgG subclass deficiency (IgGSD) with subnormal IgG2 are inadequately characterized.MethodsWe retrospectively analyzed observations in unrelated adults with IgGSD evaluated in a single hematology clinic (1991-2019) and selected t
Externí odkaz:
https://doaj.org/article/9ff85addbb924cfaa0d712b066c987c9
Autor:
James C Barton, Howard H Wiener, Ronald T Acton, Paul C Adams, John H Eckfeldt, Victor R Gordeuk, Emily L Harris, Christine E McLaren, Helen Harrison, Gordon D McLaren, David M Reboussin
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232125 (2020)
BackgroundFew cross-sectional studies report iron deficiency (ID) prevalence in women of different race/ethnicity and ages in US or Canada.Materials and methodsWe evaluated screening observations on women who participated between 2001-2003 in a cross
Externí odkaz:
https://doaj.org/article/87680c72321248f2bb7d466c6ba83ce4
Autor:
Victor R Gordeuk, Laura Lovato, James C Barton, Mara Vitolins, Gordon McLaren, Ronald T Acton, Christine McLaren, Emily L Harris, Mark Speechley, John H Eckfeldt, Sharmin Diaz, Phyliss Sholinsky, Paul Adams
Publikováno v:
Canadian Journal of Gastroenterology, Vol 26, Iss 6, Pp 345-349 (2012)
BACKGROUND: HFEC282Y homozygotes have an increased risk for developing increased iron stores and related disorders. It is controversial whether dietary iron restrictions should be recommended to such individuals.
Externí odkaz:
https://doaj.org/article/0fcd250d0a9341a593f6de72e95f5ce4
Autor:
Paul C Adams, James C Barton, Gordon D McLaren, Ronald T Acton, Mark Speechley, Christine E McLaren, David M Reboussin, Catherine Leiendecker-Foster, Emily L Harris, Beverly M Snively, Thomas Vogt, Phyliss Sholinsky, Elizabeth Thomson, Fitzroy W Dawkins, Victor R Gordeuk, John H Eckfeldt
Publikováno v:
Canadian Journal of Gastroenterology, Vol 23, Iss 11, Pp 769-772 (2009)
BACKGROUND: The HEmochromatosis and IRon Overload Screening (HEIRS) Study provided data on a racially, ethnically and geographically diverse cohort of participants in North America screened from primary care populations.
Externí odkaz:
https://doaj.org/article/6e53e75d0a134cf2a8ea25d468034d8f
Autor:
Gordon D McLaren, Christine E McLaren, Paul C Adams, James C Barton, David M Reboussin, Victor R Gordeuk, Ronald T Acton, Emily L Harris, Mark R Speechley, Phyliss Sholinsky, Fitzroy W Dawkins, Beverly M Snively, Thomas M Vogt, John H Eckfeldt, for the Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators
Publikováno v:
Canadian Journal of Gastroenterology, Vol 22, Iss 11, Pp 923-930 (2008)
BACKGROUND: Patients with hemochromatosis may suffer organ damage from iron overload, often with serious clinical consequences.
Externí odkaz:
https://doaj.org/article/3c6c7556d4464ce498ebe6998618e4c6
Autor:
Paul C Adams, Christine E McLaren, Mark Speechley, Gordon D McLaren, James C Barton, John H Eckfeldt
Publikováno v:
Canadian Journal of Gastroenterology, Vol 27, Iss 7, Pp 390-392 (2013)
BACKGROUND: Many patients referred for an elevated serum ferritin level
Externí odkaz:
https://doaj.org/article/646ac36f94da454ab432c33780c9fa2a
Autor:
Mónica Costa, Eugénia Cruz, James C Barton, Ketil Thorstensen, Sandra Morais, Berta M da Silva, Jorge P Pinto, Cristina P Vieira, Jorge Vieira, Ronald T Acton, Graça Porto
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79990 (2013)
Hereditary Hemochromatosis (HH) is a recessively inherited disorder of iron overload occurring commonly in subjects homozygous for the C282Y mutation in HFE gene localized on chromosome 6p21.3 in linkage disequilibrium with the human leukocyte antige
Externí odkaz:
https://doaj.org/article/13641154c1294ce6be1d92679f3b4513