Zobrazeno 1 - 10
of 20
pro vyhledávání: '"James B. Reinecke"'
Autor:
James B. Reinecke, Amanda J. Saraf, John M. Hinckley, Amy C. Gross, Helene Le Pommellette, Sophia Vatelle, Matthew V. Cannon, Emily Franz, Maren Cam, Ryan D. Roberts
Publikováno v:
Cancer Research. 83:64-64
Metastasis remains the primary cause of morbidity in most solid tumors, yet the mechanisms by which tumors colonize distant tissues remain poorly understood. Osteosarcoma illustrates the need to address this knowledge gap—about 40% of patients diag
Publikováno v:
Clinical Cancer Research. 28:B016-B016
Osteosarcoma is the most common pediatric bone tumor. Death from osteosarcoma is almost always due to metastatic spread to the lungs, which largely occurs after the primary tumor has been resected and treated with chemotherapy. Others have suggested
Publikováno v:
Cancer Research. 82:2511-2511
Four decades of intense effort have not improved outcomes for patients with osteosarcoma. Even though 35-40% of young people so treated still die from the disease, usually from complications related to lung metastasis, our standard of care remains un
Autor:
Amy C. Gross, James B. Reinecke, Amanda Saraf, Helene LePommellet, Sophia Vatelle, Ryan D. Roberts
Publikováno v:
Cancer Research. 82:2509-2509
Osteosarcoma is the most common pediatric bone tumor. Death from osteosarcoma is almost always due to metastatic spread to the lungs, which largely occurs after the primary tumor has been resected and treated with chemotherapy. Others have suggested
Autor:
Rosdali Diaz-Coronado, James B Reinecke, Joseph R Stanek, Jonathan L Finlay, Eddy Hernandez-Broncano, Sharon Chavez-Paredes, Yesenia Miranda-Tunque, Adela Heredia-Zelaya, Sandro Casavilca-Zambrano, Pamela Garcia-Corrochano, Luis Ojeda-Medina, Enrique Orrego-Puelles, Ebert Torres-Malca, Raymundo Sernaque-Quintana, William Quispe-Valverde, Juan Garcia-Leon, Diana S Osorio
Publikováno v:
Neuro-Oncology. 24:i167-i167
BACKGROUND: Medulloblastoma is the most common malignant brain tumor in children. While survival has improved in high-income countries (HIC), the outcomes for patients in low-middle-income countries (LMIC) are unclear. Therefore, we sought to determi
Autor:
Benjamin J. Nichols, Gregory C. Rogers, Steven H Caplan, Kriti Bahl, Trey Farmer, Shuwei Xie, Ivana Yeow, Naava Naslavsky, Tiffany A. McLamarrah, James B. Reinecke
Publikováno v:
Molecular Biology of the Cell
Centrosomes are the major microtubule-nucleating and microtubule-organizing centers of cells and play crucial roles in microtubule anchoring, organelle positioning, and ciliogenesis. At the centrosome core lies a tightly associated or “engaged” m
Autor:
James B Reinecke, Sarah L DeVos, James P McGrath, Amanda M Shepard, Dustin K Goncharoff, Don N Tait, Samantha R Fleming, Michael P Vincent, Michelle L Steinhilb
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23865 (2011)
Alzheimer's disease and other related neurodegenerative disorders known as tauopathies are characterized by the accumulation of abnormally phosphorylated and aggregated forms of the microtubule-associated protein tau. Several laboratories have identi
Externí odkaz:
https://doaj.org/article/6b18e7488c294543af57f18c848bbca1
Publikováno v:
Journal of pediatric hematology/oncology. 41(4)
Background Frequent surveillance of bacterial pathogens responsible for microbiologically defined-blood stream infections (MD-BSI), and their respective antibiotic susceptibilities is central to tailoring empiric antibiotic therapy in febrile neutrop
Publikováno v:
Journal of Cell Science.
Mitochondria play essential roles in cellular energy processes, including ATP production, control of reactive oxygen species (ROS) and apoptosis. While mitochondrial function is regulated by the dynamics of fusion and fission, mitochondrial homeostas
Publikováno v:
Traffic. 16:48-67
During interphase, recycling endosomes mediate the transport of internalized cargo back to the plasma membrane. However, in mitotic cells, recycling endosomes are essential for the completion of cytokinesis, the last phase of mitosis that promotes th