Zobrazeno 1 - 10
of 51
pro vyhledávání: '"James B. Knaak"'
Autor:
James B. Knaak
Reviews of Environmental Contamination and Toxicology attempts to provide concise, critical reviews of timely advances, philosophy and significant areas of accomplished or needed endeavor in the total field of xenobiotics, in any segment of the envir
Health Risk Assessment is a comprehensive reference focusing on dermal absorption, cholinesterase inhibition, adverse reproductive effects, and carcinogenicity. The book features contributions from over 40 top scientists and covers topics such as PBP
Autor:
Frederick W. Power, Andy M. Tsang, Lynda S. Harrison, Curtis C. Dary, James B. Knaak, Xiaofei Zhang, Miles S. Okino
Publikováno v:
Toxicological Sciences. 100:345-359
Carbofuran (2,3-dihydro-2,2-dimethyl-7-benzofuranyl-N-methylcarbamate), a broad spectrum N-methyl carbamate insecticide, and its metabolite, 3-hydroxycarbofuran, exert their toxicity by reversibly inhibiting acetylcholinesterase (AChE). To characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd34b954c4aef96a6c8d6153f7d4234c
https://doi.org/10.1093/toxsci/kfm232
https://doi.org/10.1093/toxsci/kfm232
Autor:
James B. Knaak, James R. Olson, Robert J. Foxenberg, Barbara P. McGarrigle, Paul J. Kostyniak
Publikováno v:
Drug Metabolism and Disposition. 35:189-193
Organophosphorus pesticides (OPs) remain a potential concern to human health because of their continuing worldwide use. Thiophosphorus OPs, once bioactivated by cytochromes P450 (P450s), form oxon metabolites, which are potent acetylcholinesterase in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94f7a418c7aad9a4fc71e43b1f2164a
https://doi.org/10.1124/dmd.106.012427
https://doi.org/10.1124/dmd.106.012427
Autor:
Pamela J. Lein, Fayssal M. Farahat, Steven T. Singleton, James B. Knaak, Matthew R. Bonner, James R. Olson, Taghreed M Farahat
Publikováno v:
Singleton, Steven T; Lein, Pamela J; Farahat, Fayssal M; Farahat, Taghreed; Bonner, Matthew R; Knaak, James B; et al.(2014). Characterization of α-cypermethrin exposure in Egyptian agricultural workers.. International journal of hygiene and environmental health, 217(4-5), 538-545. doi: 10.1016/j.ijheh.2013.10.003. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/7tg5v58h
International journal of hygiene and environmental health, vol 217, iss 4-5
International journal of hygiene and environmental health, vol 217, iss 4-5
Pyrethroids are neurotoxic insecticides that exert their effects by prolonging the open time of sodium channels, which increases the duration of neuronal excitation. α-cypermethrin (αCM) is derived from the 8-stereoisomers that together make up the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99d002fa182e466f73d2e87233137e8
http://www.escholarship.org/uc/item/7tg5v58h
http://www.escholarship.org/uc/item/7tg5v58h
Autor:
James B. Knaak, Charles Timchalk, Rogelio Tornero-Velez, M. R. Goldsmith, J. C. Johnson, D. T. Chang, R. Tornero-Velez, J. B. Knaak, Curtis C. Dary, Robert W. Gerlach, Masahiko Okamoto, Hideo Kaneko, J. V. Bruckner, T. G. Osmitiz, S. Anand, D. Minnema, W. Schmitt, N. Assaf, J. Zastre, Mai A. Ngo, Howard I. Maibach, William G. Reifenrath, Ernest Hodgson, Andrew D. Wallace, Clement E. Furlong, Rebecca J. Richter, Lucio G. Costa, Gail P. Jarvik, Matthew K. Ross, Mariola J. Edelmann, Virginia C. Moser, Janice E. Chambers, Edward C. Meek, Howard W. Chambers, Jordan Ned Smith, Andrea Hjerpe, Torka S. Poet, Sookwang Lee, David M. Soderlund, Michael F. Hughes, Melissa P. L. Chan, James M. Starr, Timothy J. Shafer, Edward J. Scollon, Michael J. DeVito, Daniel T. Chang, Michael-Rock Goldsmith, Yu-Mei Tan, Christopher M. Grulke, Ling-Jen Chen, Elin M. Ulrich, Andrew B. Lindstrom, Melissa A. Pasquinelli, James R. Rabinowitz, Christopher D. Ruark, C. Eric Hack, Peter J. Robinson, Jeffery M. Gearhart, Jimena L. Davis, R. Woodrow Setzer, Corie A. Ellison, Robi
Autor:
Alice Crane, Pamela J. Lein, Richard W. Browne, Corie A. Ellison, James B. Knaak, Matthew R. Bonner, James R. Olson
Publikováno v:
Toxicology and applied pharmacology, vol 265, iss 3
Animal studies have shown that paraoxonase 1 (PON1) genotype can influence susceptibility to the organophosphorus pesticide chlorpyrifos (CPF). However, Monte Carlo analysis suggests that PON1 genotype may not affect CPF-related toxicity at low expos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1781ff247f6a350689645fa722a55a
https://escholarship.org/uc/item/6tp7n6xt
https://escholarship.org/uc/item/6tp7n6xt
Autor:
James B. Knaak
Publikováno v:
Toxicology Letters. 79:305-312
Industry continues to promote the use of sound science in regulatory decision making. The use of decision support methodologies for hazard identification/risk assessment of toxic substances such as models employing physiologically based pharmacokinet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd36b989955831b2aa709f00b4bf094c
https://doi.org/10.1016/0378-4274(95)03383-v
https://doi.org/10.1016/0378-4274(95)03383-v
Publikováno v:
Progress in molecular biology and translational science. 112
The federal laws and regulations governing the registration and use of pesticides in the United States under the Federal Insecticide, Fungicide, and Rodenticide Act are published in the Federal Register, while state laws such as California are publis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9fcb6eb61071ec151e990bd67b159f0
https://pubmed.ncbi.nlm.nih.gov/22974739
https://pubmed.ncbi.nlm.nih.gov/22974739
Autor:
James B, Knaak, Curtis C, Dary, Xiaofei, Zhang, Robert W, Gerlach, R, Tornero-Velez, Daniel T, Chang, Rocky, Goldsmith, Jerry N, Blancato
Publikováno v:
Reviews of environmental contamination and toxicology. 219
In this review we have examined the status of parameters required by pyrethroid QSAR-PBPK/PD models for assessing health risks. In lieu of the chemical,biological, biochemical, and toxicological information developed on the pyrethroids since 1968, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e54b6061407ad79f7877199c1a45f73
https://pubmed.ncbi.nlm.nih.gov/22610175
https://pubmed.ncbi.nlm.nih.gov/22610175