Výsledky vyhledávání - "James B. Gerstner"

A randomized Phase II trial of two dosage levels of letrozole as third-line hormonal therapy for women with metastatic breast carcinoma

Autor: Alan K. Hatfield, Vera J. Suman, James B. Gerstner, Lynn C. Hartmann, Patricia A. Johnson, Charles L. Loprinzi, Dean H. Gesme, John K. Camoriano, James N. Ingle, James A. Mailliard

Publikováno v: Cancer. 80:218-224

BACKGROUND It is common practice to utilize a series of different hormonal agents in the treatment of postmenopausal women who, despite disease progression, continue to be candidates for hormonal therapy on a clinical basis. Letrozole is a new highly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::05680c7bc3c13dff5ff5f2a5fa237cbe
https://doi.org/10.1002/(sici)1097-0142(19970715)80:2<218::aid-cncr8>3.0.co

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Phase III controlled evaluation of sucralfate to alleviate stomatitis in patients receiving fluorouracil-based chemotherapy

Autor: Paul J. Novotny, Susan K. Quella, John C. Michalak, Paul L. Schaefer, D. F. White, Jeff A. Sloan, Charles L. Loprinzi, Preston D. Steen, James B. Gerstner, A K Hatfield, Chirantan Ghosh, John K. Camoriano

Publikováno v: Journal of Clinical Oncology. 15:1235-1238

PURPOSE Stomatitis is a major dose-limiting toxicity of bolus fluorouracil (5FU)-based chemotherapy regimens, despite the use of oral cryotherapy. Pursuant to preliminary data that suggested a sucralfate oral solution could alleviate chemotherapy-ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a065c1eafef76daff3358c5576425d0
https://doi.org/10.1200/jco.1997.15.3.1235

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Controlled clinical trial of interferon-gamma as postoperative surgical adjuvant therapy for colon cancer

Autor: James E. Krook, James A. Mailliard, R J Fitzgibbons, Nick J. Gonchoroff, Michael J. O'Connell, James B. Gerstner, Harry S. Wieand, John H. Donohue, Martin Wiesenfeld, R Pazdur

Publikováno v: Journal of Clinical Oncology. 13:2324-2329

PURPOSE The primary goal of this study was to assess the effectiveness of interferon gamma (IFN-gamma) to prevent tumor relapse following potentially curative surgery in patients with high-risk colon cancer. A secondary goal was to determine the effe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de48ef51f325f64814fa34b078b4f7a
https://doi.org/10.1200/jco.1995.13.9.2324

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Randomized placebo-controlled evaluation of hydrazine sulfate in patients with advanced colorectal cancer

Autor: Charles L. Loprinzi, Dean H. Gesme, Richard M. Goldberg, Steven A. Kuross, Judith R. O'Fallon, Raylene M. Rospond, James B. Gerstner, Charles D. Cobau

Publikováno v: Journal of Clinical Oncology. 12:1121-1125

PURPOSE Hydrazine sulfate is a controversial agent that was originally studied in cancer patients approximately 20 years ago. Based on a series of recent trials that suggested that this drug might have utility in cancer patients, we conducted this st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7cb08071b4054e5e99ed3dee9178c3d0
https://doi.org/10.1200/jco.1994.12.6.1121

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DNA ploidy and percent S-phase as prognostic factors in node-positive breast cancer: results from patients enrolled in two prospective randomized trials

Autor: Daniel J. Schaid, Clive S. Grant, James N. Ingle, James E. Krook, Jerry A. Katzmann, Nick J. Gonchoroff, Lester E. Wold, Thomas E. Witzig, James B. Gerstner, John F. Barlow

Publikováno v: Journal of Clinical Oncology. 11:351-359

PURPOSE AND METHODS To help clarify the clinical utility of flow-cytometric parameters, we performed flow cytometry on archival paraffin-embedded primary breast cancers from 502 patients treated on two adjuvant chemotherapy protocols performed by the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74eef032414fa563cf1206304096b0b
https://doi.org/10.1200/jco.1993.11.2.351

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Phase II Study of High-Dose Somatostatin Analogue in Patients Either Previously Treated or Untreated Who Have Extensive-Stage Small Cell Lung Cancer

Autor: Robert F. Marschke, James B. Gerstner, Donald B. Wender, James A. Mailliard, Roscoe F. Morton, Chirantan Ghosh, James R. Jett, Ralph Levitt, Joseph P. Grill, Jeff A. Sloan

Publikováno v: American Journal of Clinical Oncology. 22:15-17

The authors conducted a phase II study of somatostatin analogue in 18 patients with extensive stage small cell lung cancer (four with previous treatment, 14 without previous treatment). Patients received 2,000 mg subcutaneously thrice daily. They wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f409aeaabaad4450f87bd98ac11c3bdc
https://doi.org/10.1097/00000421-199902000-00004

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A phase ii study of the combination of etoposide and cisplatin in the therapy of advanced gastric cancer

Autor: Richard G. Hahn, James B. Gerstner, Charles G. Moertel, James A. Mailliard, Thomas E. Elliott, Harry S. Wieand, Loren K. Tschetter

Publikováno v: Cancer. 65:1491-1494

Forty-eight patients with advanced gastric cancer and measurable areas of malignant disease were treated with etoposide (130 mg/mz/day X 3 days) plus cisplatin (45 mg/mzday on days 2 and 3). Both drugs were given by constant intravenous infusion and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d6e7a8897b8a347414ade6230409bdb
https://doi.org/10.1002/1097-0142(19900401)65:7<1491::aid-cncr2820650707>3.0.co

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Phase II Study of Docetaxel in Advanced Soft Tissue Sarcomas

Autor: James B. Gerstner, Harry Mcgaw, Sin-Ho Jung, Antonio G. Nascimento, Larry P. Ebbert, John H. Edmonson

Publikováno v: American Journal of Clinical Oncology. 19:574-576

Because of its unusual mechanism of action, docetaxel was selected for study in advanced soft tissue sarcomas of adults as part of a search for new active antisarcoma agents. Patients at least 18 years old with measurable histologically proven advanc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdac35baf7830eefba7774c5bd606338
https://doi.org/10.1097/00000421-199612000-00008

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Phase III comparison of twice-daily split-course irradiation versus once-daily irradiation for patients with limited stage small-cell lung carcinoma

Autor: Ralph Levitt, Thomas G. Shanahan, Andrew Maksymiuk, Burke J. Brooks, Jeff A. Sloan, Shauna Hillman, James R. Jett, James B. Gerstner, James A. Mailliard, Randolph S. Marks, James E. Krook, James A. Bonner, Henry D. Tazelaar

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 17(9)

PURPOSE: Because small-cell lung cancer is a rapidly proliferating tumor, it was hypothesized that it may be more responsive to thoracic irradiation (TI) given twice-daily than once-daily. This hypothesis was tested in a phase III trial. PATIENTS AND

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e9dc55d3111e5615abc243b07f3677
https://pubmed.ncbi.nlm.nih.gov/10561342

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Paclitaxel and G-CSF in previously untreated patients with extensive stage small-cell lung cancer: a phase II study of the North Central Cancer Treatment Group

Autor: John W. Kugler, Joseph P. Grill, James R. Jett, Steven A. Kuross, Ron J. Kirschling, Keith D. Krewer, Harold E. Windschitl, James B. Gerstner, Randolph S. Marks, John C. Michalak

Publikováno v: American journal of clinical oncology. 22(5)

Paclitaxel is an antimicrotubule agent that interferes with cell division. It has demonstrated promising single-agent activity against non-small-cell lung cancer. The purpose of this study was to evaluate the therapeutic effectiveness of paclitaxel i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4062897be09b9549a1b9e008779733be
https://pubmed.ncbi.nlm.nih.gov/10521070

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