Zobrazeno 1 - 8 of 8 pro vyhledávání: '"James B Olesen"'
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Loss of protein quality control gene UBR1 sensitizes Saccharomyces cerevisiae to the aminoglycoside hygromycin B
Autor: James B. Olesen, Avery M. Runnebohm, Adam E. Richardson, Philip J. Smaldino, Samantha M. Turk, Melissa D Evans, Eric M. Rubenstein
Publikováno v: Fine Focus
Ubr1 is a conserved ubiquitin ligase involved in the degradation of aberrant proteins in eukaryotic cells. The human enzyme is found mutated in patients with Johanson-Blizzard syndrome. We hypothesized that Ubr1 is necessary for optimal cellular fitn
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d008930e3bc8f627eaa7c94eeaf3fe7
https://doi.org/10.33043/ff.6.1.76-83
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3
Inner Nuclear Membrane Asi Ubiquitin Ligase Catalytic Subunits Asi1p and Asi3p, but not Asi2p, confer resistance to aminoglycoside hygromycin B in
Autor: Kelsey A, Woodruff, Kyle A, Richards, Melissa D, Evans, Abigail R, Scott, Brian M, Voas, Courtney Broshar, Irelan, James B, Olesen, Philip J, Smaldino, Eric M, Rubenstein
Publikováno v: microPublication Biology
The heterotrimeric Asi ubiquitin ligase (encoded by ASI1, ASI2, and ASI3) mediates protein degradation in the inner nuclear membrane in Saccharomyces cerevisiae. Asi1p and Asi3p possess catalytic domains, while Asi2p functions as an adaptor for a sub
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9536e4658b32b8501e50aefe2384e495
https://pubmed.ncbi.nlm.nih.gov/34095778
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4
Akademický článek
Colchitaxel, a coupled compound made from microtubule inhibitors colchicine and paclitaxel
Autor: Karunananda Bombuwala, Thomas Kinstle, Vladimir Popik, Sonal O. Uppal, James B. Olesen, Jose Viña, Carol A. Heckman
Publikováno v: Beilstein Journal of Organic Chemistry, Vol 2, Iss 1, p 13 (2006)
BackgroundTumor promoters enhance tumor yield in experimental animals without directly affecting the DNA of the cell. Promoters may play a role in the development of cancer, as humans are exposed to them in the environment. In work based on computer-
Externí odkaz: https://doaj.org/article/32e97f442cec4b1abd7e7b39e1783d8f
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5
Colchitaxel, a coupled compound made from microtubule inhibitors colchicine and paclitaxel
Autor: Jose Viña, Vladimir V. Popik, Karunananda Bombuwala, Sonal Uppal, Thomas H. Kinstle, Carol A. Heckman, James B. Olesen
Publikováno v: Beilstein Journal of Organic Chemistry, Vol 2, Iss 1, p 13 (2006)
Beilstein Journal of Organic Chemistry
BackgroundTumor promoters enhance tumor yield in experimental animals without directly affecting the DNA of the cell. Promoters may play a role in the development of cancer, as humans are exposed to them in the environment. In work based on computer-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ebaa6c7e7250c62a9a3fe9ea1b1e542
https://doaj.org/article/32e97f442cec4b1abd7e7b39e1783d8f
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7
Determining chromatin structure by computer-aided image analysis
Autor: Carol A. Heckman, James B. Olesen
Publikováno v: Proceedings, annual meeting, Electron Microscopy Society of America. 51:222-223
In the present research, we address the problem of how chromatin fibers are ordered in band and interband regions along the length of a Drosophila polytene chromosome. Our approach employs image processing as a preliminary step to amplify the image c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a991f500143a7449d59ed665244d34a6
https://doi.org/10.1017/s0424820100146953
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8
Conference
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