Zobrazeno 1 - 10
of 167
pro vyhledávání: '"James B Mahony"'
Autor:
David C Bulir, Daniel A Waltho, Christopher B Stone, Kenneth A Mwawasi, Jordan C Nelson, James B Mahony
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99315 (2014)
Pathogenic Gram-negative bacteria use type III secretion (T3S) to inject effector proteins into the host cell to create appropriate conditions for infection and intracellular replication. Chlamydia spp. are believed to use T3S to infect their host ce
Externí odkaz:
https://doaj.org/article/b5518569ab9544f9a2b249ad4c6f0433
Autor:
Chris B Stone, Seiji Sugiman-Marangos, David C Bulir, Rob C Clayden, Tiffany L Leighton, Jerry W Slootstra, Murray S Junop, James B Mahony
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30220 (2012)
Type III secretion (T3S) is an essential virulence factor used by gram-negative pathogenic bacteria to deliver effector proteins into the host cell to establish and maintain an intracellular infection. Chlamydia is known to use T3S to facilitate inva
Externí odkaz:
https://doaj.org/article/e62ca6d9957b4c2f961a06e85a0ec0d3
Autor:
Chris Blair Stone, David C Bulir, Connor A Emdin, Ryan M Pirie, Elisa A Porfilio, Jerry W Slootstra, James B Mahony
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 2 (2011)
Chlamydiae are obligate intracellular pathogens that likely require type III secretion (T3S) to invade cells and replicate intracellulary within a cytoplasmic vacuole called an inclusion body. C. pneumoniae possess a YscL ortholog, CdsL, that has bee
Externí odkaz:
https://doaj.org/article/3553716885c44a23b32d99d1ed1f6255
Autor:
Chris B. Stone, David C. Bulir, Connor A. Emdin, Ryan M. Pirie, Elisa A. Porfilio, Jerry W. Slootstra, James B. Mahony
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/cb8f564ca96a498382275efa1268f52c
Autor:
James B. Mahony, Steven Liang
Publikováno v:
Journal of Vaccines and Immunology. :010-017
Chlamydia is the most common sexually transmitted infection of bacterial origin, and a broadly protective vaccine is urgently needed given the largely asymptomatic nature of the infection and the severe reproductive sequelae in women with untreated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db2383bfb18c5e08eff5c46090cadb77
https://doi.org/10.17352/jvi.000030
https://doi.org/10.17352/jvi.000030
Publikováno v:
Methods (San Diego, Calif.)
Highlights • NxTAG chemistry offers an easy workflow, low hands-on-time and scalable throughput. • All post-extraction assay steps take place in a single, closed tube. • Clinical performance of NxTAG RPP is comparable to that of the xTAG RVP as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0397a1a6ff1584d6afd25e90f8b7101e
https://doi.org/10.1016/j.ymeth.2019.01.005
https://doi.org/10.1016/j.ymeth.2019.01.005
Autor:
Katherine Radford, Sergei I. Ochkur, Ana Catuneanu, James J. Lee, Chynna Margaret Huang, Manali Mukherjee, Elizabeth A. Jacobsen, James B. Mahony, Paige Lacy, Melanie Kjarsgaard, Parameswaran Nair, Hanah Lamothe-Kipnes, David Bulir
Publikováno v:
Journal of Allergy and Clinical Immunology. 141:1269-1279
Background The persistence of eosinophils in sputum despite high doses of corticosteroids indicates disease severity in asthmatic patients. Chronic inflamed airways can lose tolerance over time to immunogenic entities released on frequent eosinophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930d69418c4db4a15a3dd799011fbf1e
https://doi.org/10.1016/j.jaci.2017.06.033
https://doi.org/10.1016/j.jaci.2017.06.033
Autor:
Steven, Liang, James B, Mahony
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2042
An appropriate means of quantitating infectious Chlamydia from infected animals is essential for the evaluation of vaccines. However, unlike methods involving culture, nonculture methods, including detection of antigen or DNA, are not able to differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c569efa078f1913cc874a578dbbf6ffa
https://pubmed.ncbi.nlm.nih.gov/31385280
https://pubmed.ncbi.nlm.nih.gov/31385280
Autor:
Steven Liang, James B. Mahony
Publikováno v:
Chlamydia trachomatis ISBN: 9781493996933
An appropriate means of quantitating infectious Chlamydia from infected animals is essential for the evaluation of vaccines. However, unlike methods involving culture, nonculture methods, including detection of antigen or DNA, are not able to differe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a45d8a95b6e00125710ced8acf675925
https://doi.org/10.1007/978-1-4939-9694-0_16
https://doi.org/10.1007/978-1-4939-9694-0_16
Autor:
Bonita E. Lee, B Louise Giles, Val Panzov, Michael H. Young, Marguerite Dennis, Charles Hui, Theo J Moraes, Johanne Morel, Judith Hall, Muhammad Mamdani, Depeng Jiang, Joan L. Robinson, Anna Banerji, Danny Bisson, James B. Mahony, Bosco Paes
Publikováno v:
CMAJ Open
BACKGROUND It is unknown whether this burden of disease of lower respiratory tract infections is comparable across the Canadian Arctic. The objectives of this surveillance study were to compare the rates of hospital admission for lower respiratory tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de15e5d6ee9dd7b44ac34f4079f70930
https://doi.org/10.9778/cmajo.20150051
https://doi.org/10.9778/cmajo.20150051