Zobrazeno 1 - 10
of 293
pro vyhledávání: '"James B Kaper"'
Autor:
Tracy H Hazen, Sean C Daughtery, Amol eShetty, Anup A Mahurkar, Owen eWhite, James B Kaper, David A Rasko
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Enteropathogenic Escherichia coli (EPEC) are a leading cause of diarrheal illness among infants in developing countries. E. coli isolates classified as typical EPEC are identified by the presence of the locus of enterocyte effacement (LEE) and the bu
Externí odkaz:
https://doaj.org/article/615e6733f4cf49ff9038ba697416dd54
Autor:
Jonathan A Levine, Anne-Marie Hansen, Jane M Michalski, Tracy H Hazen, David A Rasko, James B Kaper
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86618 (2014)
Enteropathogenic E. coli (EPEC) and enterohemorrhagic E. coli are important causes of morbidity and mortality worldwide. These enteric pathogens contain a type III secretion system (T3SS) responsible for the attaching and effacing (A/E) lesion phenot
Externí odkaz:
https://doaj.org/article/2cada9974ef84a86ab2cb958e2ddf072
Autor:
Anne-Marie Hansen, Raghothama Chaerkady, Jyoti Sharma, J Javier Díaz-Mejía, Nidhi Tyagi, Santosh Renuse, Harrys K C Jacob, Sneha M Pinto, Nandini A Sahasrabuddhe, Min-Sik Kim, Bernard Delanghe, Narayanaswamy Srinivasan, Andrew Emili, James B Kaper, Akhilesh Pandey
Publikováno v:
PLoS Pathogens, Vol 9, Iss 6, p e1003403 (2013)
While phosphotyrosine modification is an established regulatory mechanism in eukaryotes, it is less well characterized in bacteria due to low prevalence. To gain insight into the extent and biological importance of tyrosine phosphorylation in Escheri
Externí odkaz:
https://doaj.org/article/c699f682d7b649178d84fe149316c4c5
Autor:
Julie In, Valeriy Lukyanenko, Jennifer Foulke-Abel, Ann L Hubbard, Michael Delannoy, Anne-Marie Hansen, James B Kaper, Nadia Boisen, James P Nataro, Chengru Zhu, Edgar C Boedeker, Jorge A Girón, Olga Kovbasnjuk
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69196 (2013)
Life-threatening intestinal and systemic effects of the Shiga toxins produced by enterohemorrhagic Escherichia coli (EHEC) require toxin uptake and transcytosis across intestinal epithelial cells. We have recently demonstrated that EHEC infection of
Externí odkaz:
https://doaj.org/article/bbda392d092543809b3e5c6ebe2ea655
Autor:
Christina S Faherty, Jill M Harper, Terez Shea-Donohue, Eileen M Barry, James B Kaper, Alessio Fasano, James P Nataro
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49980 (2012)
Shigella flexneri is a Gram-negative, facultative intracellular pathogen that causes millions of cases of watery or bloody diarrhea annually, resulting in significant global mortality. Watery diarrhea is thought to arise in the jejunum, and subsequen
Externí odkaz:
https://doaj.org/article/27918a54aa43463796d18bf5a87cef71
Autor:
Hayley J Newton, Jaclyn S Pearson, Luminita Badea, Michelle Kelly, Mark Lucas, Gavan Holloway, Kylie M Wagstaff, Michelle A Dunstone, Joan Sloan, James C Whisstock, James B Kaper, Roy M Robins-Browne, David A Jans, Gad Frankel, Alan D Phillips, Barbara S Coulson, Elizabeth L Hartland
Publikováno v:
PLoS Pathogens, Vol 6, Iss 5, p e1000898 (2010)
Many bacterial pathogens utilize a type III secretion system to deliver multiple effector proteins into host cells. Here we found that the type III effectors, NleE from enteropathogenic E. coli (EPEC) and OspZ from Shigella, blocked translocation of
Externí odkaz:
https://doaj.org/article/db95da39b4bb43fb9bafe6e7de4ba46d
Autor:
Jennifer Foulke-Abel, Huimin Yu, Laxmi Sunuwar, Ruxian Lin, James M. Fleckenstein, James B. Kaper, Mark Donowitz
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
Diarrhea caused by enterotoxigenic Escherichia coli (ETEC) has a continuing impact on residents and travelers in underdeveloped countries. Both heat-labile (LT) and heat-stable (ST) enterotoxins contribute to pathophysiology via induction of cyclic n
Externí odkaz:
https://doaj.org/article/16f91fadd30948fb9fd01350ba13a021
Publikováno v:
Expert Review of Vaccines, Vol 16, Iss 3, Pp 197-213 (2017)
Introduction: Cholera remains a problem in developing countries and a risk for travelers. Hypochlorhydria, blood group O, cardiac and renal disease increase the risk of developing cholera gravis. Oral vaccines containing inactivated Vibrio cholerae a
Externí odkaz:
https://doaj.org/article/835fdf3a8a794bfa8376c16df19d275b
Publikováno v:
Metabolites; Volume 11; Issue 12; Pages: 841
Metabolites
Metabolites, Vol 11, Iss 841, p 841 (2021)
Metabolites
Metabolites, Vol 11, Iss 841, p 841 (2021)
Colonic epithelium–commensal interactions play a very important role in human health and disease development. Colonic mucus serves as an ecologic niche for a myriad of commensals and provides a physical barrier between the epithelium and luminal co
Publikováno v:
Methods in Molecular Biology ISBN: 9781071613382
Human intestinal organoid cultures established from crypt-derived stem cells truly revolutionized our approach to study intestinal epithelial physiology and pathologies as they can be propagated indefinitely and preserve the genetic signature of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d0f52f75bba08a52dc15dcb101c1e54
https://doi.org/10.1007/978-1-0716-1339-9_13
https://doi.org/10.1007/978-1-0716-1339-9_13