Zobrazeno 1 - 10
of 144
pro vyhledávání: '"James B Fallon"'
Autor:
Mehrnaz Shoushtarian, Roohallah Alizadehsani, Abbas Khosravi, Nicola Acevedo, Colette M McKay, Saeid Nahavandi, James B Fallon
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241695 (2020)
Chronic tinnitus is a debilitating condition which affects 10-20% of adults and can severely impact their quality of life. Currently there is no objective measure of tinnitus that can be used clinically. Clinical assessment of the condition uses subj
Externí odkaz:
https://doaj.org/article/d23f419cf8fb4b8b92131f7b1389e22a
Autor:
Elise A. Ajay, Alex C. Thompson, Ajmal A. Azees, Andrew K. Wise, David B. Grayden, James B. Fallon, Rachael T. Richardson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Novel stimulation methods are needed to overcome the limitations of contemporary cochlear implants. Optogenetics is a technique that confers light sensitivity to neurons via the genetic introduction of light-sensitive ion channels. By contro
Externí odkaz:
https://doaj.org/article/7106d198775f496fbdf6ef3d9fe60cd7
Autor:
David A X Nayagam, Richard A Williams, Penelope J Allen, Mohit N Shivdasani, Chi D Luu, Cesar M Salinas-LaRosa, Sue Finch, Lauren N Ayton, Alexia L Saunders, Michelle McPhedran, Ceara McGowan, Joel Villalobos, James B Fallon, Andrew K Wise, Jonathan Yeoh, Jin Xu, Helen Feng, Rodney Millard, Melanie McWade, Patrick C Thien, Chris E Williams, Robert K Shepherd
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97182 (2014)
To assess the safety and efficacy of chronic electrical stimulation of the retina with a suprachoroidal visual prosthesis.Seven normally-sighted feline subjects were implanted for 96-143 days with a suprachoroidal electrode array and six were chronic
Externí odkaz:
https://doaj.org/article/9eed3a29f32240d3a09b8968ea2f0b71
Autor:
Jeremy L. Pinyon, Georg vonJonquieres, Edward N. Crawford, Amr Al Abed, John M. Power, Matthias Klugmann, Cherylea J. Browne, David M. Housley, Andrew K. Wise, James B. Fallon, Robert K. Shepherd, John Y. Lin, Catherine McMahon, David McAlpine, Catherine S. Birman, Waikong Lai, Ya Lang Enke, Paul M. Carter, James F. Patrick, Robert D. Gay, Corinne Marie, Daniel Scherman, Nigel H. Lovell, Gary D. Housley
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Viral vectors and lipofection‐based gene therapies have dispersion‐dependent transduction/transfection profiles that thwart precise targeting. The study describes the development of focused close‐field gene electrotransfer (GET) techno
Externí odkaz:
https://doaj.org/article/1f120ece41dd42df991a8e5de27489c2
Autor:
Joel Villalobos, Sophie C. Payne, Glenn M. Ward, Sofianos Andrikopoulos, Tomoko Hyakumura, Richard J. MacIsaac, James B. Fallon
Publikováno v:
Bioelectronic Medicine, Vol 9, Iss 1, Pp 1-12 (2023)
Abstract Background Autonomic nerve stimulation is used as a treatment for a growing number of diseases. We have previously demonstrated that application of efferent vagus nerve stimulation (eVNS) has promising glucose lowering effects in a rat model
Externí odkaz:
https://doaj.org/article/1a577f4927ab49309bf40323f68e3349
Autor:
Sophie C. Payne, Peregrine B. Osborne, Alex Thompson, Calvin D. Eiber, Janet R. Keast, James B. Fallon
Publikováno v:
APL Bioengineering, Vol 7, Iss 4, Pp 046110-046110-13 (2023)
Real-time closed-loop control of neuromodulation devices requires long-term monitoring of neural activity in the peripheral nervous system. Although many signal extraction methods exist, few are both clinically viable and designed for extracting smal
Externí odkaz:
https://doaj.org/article/94a917faed474ebf88f9158719316baf
Autor:
Jerico V. Matarazzo, Elise A. Ajay, Sophie C. Payne, Ella P. Trang, Alex C. Thompson, Jason B. Marroquin, Andrew K. Wise, James B. Fallon, Rachael T. Richardson
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionElectrical stimulation offers a drug-free alternative for the treatment of many neurological conditions, such as chronic pain. However, it is not easy to selectively activate afferent or efferent fibers of mixed nerves, nor their function
Externí odkaz:
https://doaj.org/article/390b477cfe604745b341045cca1699a7
Autor:
Miheng Dong, Harold A. Coleman, Mary A. Tonta, Zhiyuan Xiong, Dan Li, Sebastian Thomas, Minsu Liu, James B. Fallon, Helena C. Parkington, John S. Forsythe
Publikováno v:
Nanoscale. 14:15845-15858
The electrical and biological interfacial properties of invasive electrodes have a significant impact on the performance and longevity of neural recordings in the brain. In this study, we demonstrated rapid electrophoretic deposition and electrochemi
Publikováno v:
Frontiers in neuroscience. 16
Rheumatoid arthritis (RA) is a chronic, autoimmune inflammatory disease. Despite therapeutic advances, a significant proportion of RA patients are resistant to pharmacological treatment. Stimulation of the cervical vagus nerve is a promising alternat
Auditory nerve responses to combined optogenetic and electrical stimulation in chronically deaf mice
Autor:
Elise A Ajay, Ella P Trang, Alexander C Thompson, Andrew K Wise, David B Grayden, James B Fallon, Rachael T Richardson
Publikováno v:
Journal of Neural Engineering. 20:026035
Objective. Optogenetic stimulation of the auditory nerve offers the ability to overcome the limitations of cochlear implants through spatially precise stimulation, but cannot achieve the temporal precision nor temporal fidelity required for good hear