Zobrazeno 1 - 10
of 79
pro vyhledávání: '"James B Caress"'
Autor:
Vincent Meininger, Pierre-François Pradat, Andrea Corse, Safa Al-Sarraj, Benjamin Rix Brooks, James B Caress, Merit Cudkowicz, Stephen J Kolb, Dale Lange, P Nigel Leigh, Thomas Meyer, Stefano Milleri, Karen E Morrison, Richard W Orrell, Gary Peters, Jeffrey D Rothstein, Jeremy Shefner, Arseniy Lavrov, Nicola Williams, Phil Overend, Jeffrey Price, Stewart Bates, Jonathan Bullman, David Krull, Alienor Berges, Bams Abila, Guy Meno-Tetang, Jens Wurthner
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97803 (2014)
The neurite outgrowth inhibitor, Nogo-A, has been shown to be overexpressed in skeletal muscle in amyotrophic lateral sclerosis (ALS); it is both a potential biomarker and therapeutic target. We performed a double-blind, two-part, dose-escalation stu
Externí odkaz:
https://doaj.org/article/a10f2b867b174c858f2c458ef8e54388
Autor:
James D Berry, Jeremy M Shefner, Robin Conwit, David Schoenfeld, Myles Keroack, Donna Felsenstein, Lisa Krivickas, William S David, Francine Vriesendorp, Alan Pestronk, James B Caress, Jonathan Katz, Ericka Simpson, Jeffrey Rosenfeld, Robert Pascuzzi, Jonathan Glass, Kourosh Rezania, Jeffrey D Rothstein, David J Greenblatt, Merit E Cudkowicz, Northeast ALS Consortium
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61177 (2013)
Ceftriaxone increases expression of the astrocytic glutamate transporter, EAAT2, which might protect from glutamate-mediated excitotoxicity. A trial using a novel three stage nonstop design, incorporating Phases I-III, tested ceftriaxone in ALS. Stag
Externí odkaz:
https://doaj.org/article/410d255438ad4dbfbb830597101abc59
Publikováno v:
Clinical Neurophysiology. 147:14-16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9fed3ccf866660a75ef6b45ffe8e2c3
https://doi.org/10.1016/j.clinph.2022.12.007
https://doi.org/10.1016/j.clinph.2022.12.007
Publikováno v:
Muscle & Nerve. 64:140-152
Acute hepatic porphyrias are inherited metabolic disorders that may present with polyneuropathy, which if not diagnosed early can lead to quadriparesis, respiratory weakness, and death. Porphyric neuropathy is an acute to subacute motor predominant a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24299c3066540d71af70f260d6b94b6
https://doi.org/10.1002/mus.27232
https://doi.org/10.1002/mus.27232
Autor:
Michael S. Bereman, Terry Heiman Patterson, Paul Wicks, Paul E. Barkhaus, Kristiana Salmon, Richard Bedlack, James B. Caress, Sky Kihuwa-mani, Gregory T. Carter, Gary L. Pattee, Neta Zach, Jesse Crayle
Publikováno v:
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 22:595-598
Here we use the ALSUntangled methodology to review Tamoxifen as an ALS treatment. We show that it has plausible mechanisms, a positive preclinical study, a case report and 2 small trials suggesting benefits. We show that it appears reasonably safe, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::645635478b5b50e6b77efc4a4cbcabc7
https://doi.org/10.1080/21678421.2021.1876731
https://doi.org/10.1080/21678421.2021.1876731
Autor:
Meghan Hall, Janet P. Wittes, Gary L. Pattee, Eric A. Macklin, Eric Tustison, Tuan Vu, Zi-Fan Yu, Samuel P. Dickson, Rudolph E. Tanzi, Liberty Jenkins, Suma Babu, Michael A. Elliott, Jonathan S. Katz, Chafic Karam, Patricia L. Andres, Terry Heiman-Patterson, Stephen N. Scelsa, Christina Fournier, Joseph Ostrow, Timothy M. Miller, Joshua N Cohen, Daragh Heitzman, Edward J. Kasarskis, Derek Dagostino, Patrick D. Yeramian, Colin Quinn, Rebecca Randall, Lindsay Pothier, James Wymer, Hong Yu, Gale Kittle, Newman Knowlton, Michelle McGovern, Shafeeq Ladha, Jason Walker, Jeffrey D. Rothstein, Adam Quick, James Chan, Kent L. Leslie, Prasha Vigneswaran, Maria E. St. Pierre, Kristin M. Johnson, Walter Gilbert, Namita Goyal, James B. Caress, Marianne Chase, Sabrina Paganoni, Jonathan D. Glass, Justin Klee, Merit Cudkowicz, Jeremy M. Shefner, Suzanne Hendrix, Carlayne E. Jackson, Margaret Owegi, James D. Berry, David A. Schoenfeld, Alexander Sherman, Stephen A. Goutman, Matthew Eydinov, Andrea Swenson, Samuel Maiser
Publikováno v:
Muscle & Nerve
An orally administered, fixed‐dose coformulation of sodium phenylbutyrate‐taurursodiol (PB‐TURSO) significantly slowed functional decline in a randomized, placebo‐controlled, phase 2 trial in ALS (CENTAUR). Herein we report results of a long
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c577e9ab26d1e9b80fcf0903d01570f
https://doi.org/10.1002/mus.27091
https://doi.org/10.1002/mus.27091
Autor:
Sabrina Paganoni, Suzanne Hendrix, Samuel P Dickson, Newman Knowlton, James D Berry, Michael A Elliott, Samuel Maiser, Chafic Karam, James B Caress, Margaret Ayo Owegi, Adam Quick, James Wymer, Stephen A Goutman, Daragh Heitzman, Terry D Heiman-Patterson, Carlayne Jackson, Colin Quinn, Jeffrey D Rothstein, Edward J Kasarskis, Jonathan Katz, Liberty Jenkins, Shafeeq S Ladha, Timothy M Miller, Stephen N Scelsa, Tuan H Vu, Christina Fournier, Kristin M Johnson, Andrea Swenson, Namita Goyal, Gary L Pattee, Suma Babu, Marianne Chase, Derek Dagostino, Meghan Hall, Gale Kittle, Mathew Eydinov, Joseph Ostrow, Lindsay Pothier, Rebecca Randall, Jeremy M Shefner, Alexander V Sherman, Eric Tustison, Prasha Vigneswaran, Hong Yu, Joshua Cohen, Justin Klee, Rudolph Tanzi, Walter Gilbert, Patrick Yeramian, Merit Cudkowicz
Publikováno v:
Journal of neurology, neurosurgery, and psychiatry, vol 93, iss 8
BackgroundCoformulated sodium phenylbutyrate/taurursodiol (PB/TURSO) was shown to prolong survival and slow functional decline in amyotrophic lateral sclerosis (ALS).ObjectiveDetermine whether PB/TURSO prolonged tracheostomy/ventilation-free survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668333e30d83e12f19bd834ace7127dc
https://pubmed.ncbi.nlm.nih.gov/35577511
https://pubmed.ncbi.nlm.nih.gov/35577511
Autor:
James B. Caress, Sapna Pathak, Michael S. Cartwright, Carol Milligan, Marlena Wosiski-Kuhn, Delaney Williams
Publikováno v:
Muscle & Nerve. 59:181-186
INTRODUCTION This study explores the reliability and responsiveness of neuromuscular ultrasound in amyotrophic lateral sclerosis (ALS). METHODS Investigations were conducted with 10 healthy controls, 10 patients with ALS (single point in time), and 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c8b5441e539086a5e2cd14be39ab43b
https://doi.org/10.1002/mus.26360
https://doi.org/10.1002/mus.26360
Autor:
Richard, Bedlack, Sky, Kihuwa-Mani, Paul E, Barkhaus, Michael, Bereman, James B, Caress, Jesse, Crayle, Gary L, Pattee, Terry, Heiman Patterson, Paul, Wicks, Neta, Zach, Gregory T, Carter, Kristiana, Salmon
Publikováno v:
Amyotrophic lateral sclerosisfrontotemporal degeneration. 22(7-8)
Here we use the ALSUntangled methodology to review Tamoxifen as an ALS treatment. We show that it has plausible mechanisms, a positive preclinical study, a case report and 2 small trials suggesting benefits. We show that it appears reasonably safe, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b03a8fd22b2d92def2d2504023b23948
https://pubmed.ncbi.nlm.nih.gov/33474997
https://pubmed.ncbi.nlm.nih.gov/33474997
Autor:
Marlena, Wosiski-Kuhn, James B, Caress, Michael S, Cartwright, Gregory A, Hawkins, Carol, Milligan
Publikováno v:
Amyotrophic lateral sclerosisfrontotemporal degeneration. 22(3-4)
Interleukin-6 (IL6) expression increases in atrophying muscles and lung tissue during compromised function. Considering ALS patients undergo these same pathological changes, IL6 levels may be relevant for prognostication and treatment. The amount of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26b118dc856ba8094a4ea767f4a33db7
https://pubmed.ncbi.nlm.nih.gov/32924606
https://pubmed.ncbi.nlm.nih.gov/32924606