Zobrazeno 1 - 10
of 110
pro vyhledávání: '"James B, Munro"'
Autor:
Shawn B. Egri, Xue Wang, Marco A. Díaz-Salinas, Jeremy Luban, Natalya V. Dudkina, James B. Munro, Kuang Shen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract The Spike glycoprotein of SARS-CoV-2 mediates viral entry into the host cell via the interaction between its receptor binding domain (RBD) and human angiotensin-converting enzyme 2 (ACE2). Spike RBD has been reported to adopt two primary con
Externí odkaz:
https://doaj.org/article/901a5ff344e64729abd4d805c01bb6f8
Autor:
Aastha Jain, Ramesh Govindan, Alex R Berkman, Jeremy Luban, Marco A Díaz-Salinas, Natasha D Durham, James B Munro
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011848 (2023)
Interaction between the Ebola virus envelope glycoprotein (GP) and the endosomal membrane is an essential step during virus entry into the cell. Acidic pH and Ca2+ have been implicated in mediating the GP-membrane interaction. However, the molecular
Externí odkaz:
https://doaj.org/article/9aecf8f6e6ae4f2eb6a171dc6fb90059
Autor:
Gillian Mbambo, Ankit Dwivedi, Olukemi O. Ifeonu, James B. Munro, Biraj Shrestha, Robin E. Bromley, Theresa Hodges, Ricky S. Adkins, Bourema Kouriba, Issa Diarra, Amadou Niangaly, Abdoulaye K. Kone, Drissa Coulibaly, Karim Traore, Amagana Dolo, Mahamadou A. Thera, Matthew B. Laurens, Ogobara K. Doumbo, Christopher V. Plowe, Andrea A. Berry, Mark Travassos, Kirsten E. Lyke, Joana C. Silva
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionHost gene and protein expression impact susceptibility to clinical malaria, but the balance of immune cell populations, cytokines and genes that contributes to protection, remains incompletely understood. Little is known about the determi
Externí odkaz:
https://doaj.org/article/4be637d5b54b4a7cbb6926e457c1deca
Autor:
Albert E. Zhou, Zalak V. Shah, Katie R. Bradwell, James B. Munro, Andrea A. Berry, David Serre, Shannon Takala-Harrison, Timothy D. O’Connor, Joana C. Silva, Mark A. Travassos
Publikováno v:
BMC Bioinformatics, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background RIFINs and STEVORs are variant surface antigens expressed by P. falciparum that play roles in severe malaria pathogenesis and immune evasion. These two highly diverse multigene families feature multiple paralogs, making their clas
Externí odkaz:
https://doaj.org/article/d36a18d5a84e4f59b695a9c277819f2e
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Serine incorporator 5 (Ser5), a transmembrane protein, has recently been identified as a host antiviral factor against human immunodeficiency virus (HIV)-1 and gammaretroviruses like murine leukemia viruses (MLVs). It is counteracted by HIV-
Externí odkaz:
https://doaj.org/article/145e85a9da3e4cb39d56ca6ba3ca394f
Autor:
Marco A Díaz-Salinas, Qi Li, Monir Ejemel, Leonid Yurkovetskiy, Jeremy Luban, Kuang Shen, Yang Wang, James B Munro
Publikováno v:
eLife, Vol 11 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects cells through binding to angiotensin-converting enzyme 2 (ACE2). This interaction is mediated by the receptor-binding domain (RBD) of the viral spike (S) glycoprotein. Structural an
Externí odkaz:
https://doaj.org/article/4bcb4146207f430fa79e714c928dad55
Autor:
Kara A. Moser, Elliott F. Drábek, Ankit Dwivedi, Emily M. Stucke, Jonathan Crabtree, Antoine Dara, Zalak Shah, Matthew Adams, Tao Li, Priscila T. Rodrigues, Sergey Koren, Adam M. Phillippy, James B. Munro, Amed Ouattara, Benjamin C. Sparklin, Julie C. Dunning Hotopp, Kirsten E. Lyke, Lisa Sadzewicz, Luke J. Tallon, Michele D. Spring, Krisada Jongsakul, Chanthap Lon, David L. Saunders, Marcelo U. Ferreira, Myaing M. Nyunt, Miriam K. Laufer, Mark A. Travassos, Robert W. Sauerwein, Shannon Takala-Harrison, Claire M. Fraser, B. Kim Lee Sim, Stephen L. Hoffman, Christopher V. Plowe, Joana C. Silva
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-17 (2020)
Abstract Background Plasmodium falciparum (Pf) whole-organism sporozoite vaccines have been shown to provide significant protection against controlled human malaria infection (CHMI) in clinical trials. Initial CHMI studies showed significantly higher
Externí odkaz:
https://doaj.org/article/da4c7040d45149b5b3b71fa0feb8a7a6
Autor:
Elizabeth T. Hobbs, Stephen M. Goralski, Ashley Mitchell, Andrew Simpson, Dorjan Leka, Emmanuel Kotey, Matt Sekira, James B. Munro, Suvarna Nadendla, Rebecca Jackson, Aitor Gonzalez-Aguirre, Martin Krallinger, Michelle Giglio, Ivan Erill
Publikováno v:
Frontiers in Research Metrics and Analytics, Vol 6 (2021)
Analysis of high-throughput experiments in the life sciences frequently relies upon standardized information about genes, gene products, and other biological entities. To provide this information, expert curators are increasingly relying on text mini
Externí odkaz:
https://doaj.org/article/6563012a49b34ad48518e463b4bcd94c
Autor:
Nicholas C Palmateer, Kyle Tretina, Joshua Orvis, Olukemi O Ifeonu, Jonathan Crabtree, Elliott Drabék, Roger Pelle, Elias Awino, Hanzel T Gotia, James B Munro, Luke Tallon, W Ivan Morrison, Claudia A Daubenberger, Vish Nene, Donald P Knowles, Richard P Bishop, Joana C Silva
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 10, p e0008781 (2020)
Theileria parva is an economically important, intracellular, tick-transmitted parasite of cattle. A live vaccine against the parasite is effective against challenge from cattle-transmissible T. parva but not against genotypes originating from the Afr
Externí odkaz:
https://doaj.org/article/8f70a77d240e4115906cbd29836599c8
Autor:
Vinita R Joshi, Ruchi M Newman, Melissa L Pack, Karen A Power, James B Munro, Ken Okawa, Navid Madani, Joseph G Sodroski, Aaron G Schmidt, Todd M Allen
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008577 (2020)
The HIV-1 envelope glycoprotein (Env) mediates viral entry via conformational changes associated with binding the cell surface receptor (CD4) and coreceptor (CCR5/CXCR4), resulting in subsequent fusion of the viral and cellular membranes. While the g
Externí odkaz:
https://doaj.org/article/e3859f10b003443bab3cc267b1c5c2ec