Zobrazeno 1 - 10
of 16
pro vyhledávání: '"James Antoney"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The deazaflavin cofactor F420 is a low-potential, two-electron redox cofactor produced by some Archaea and Eubacteria that is involved in methanogenesis and methanotrophy, antibiotic biosynthesis, and xenobiotic metabolism. However, it is no
Externí odkaz:
https://doaj.org/article/32148b2317254743871f9cd92f54d262
Autor:
Ghader Bashiri, James Antoney, Ehab N. M. Jirgis, Mihir V. Shah, Blair Ney, Janine Copp, Stephanie M. Stuteley, Sreevalsan Sreebhavan, Brian Palmer, Martin Middleditch, Nobuhiko Tokuriki, Chris Greening, Colin Scott, Edward N. Baker, Colin J. Jackson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Cofactor F420 plays crucial roles in bacterial and archaeal metabolism, but its biosynthetic pathway is not fully understood. Here, the authors present the structure of one of the enzymes and provide experimental evidence for a substantial revision o
Externí odkaz:
https://doaj.org/article/dfc85bab35bc45cdb9ec5b52911c6873
Autor:
Mihir V. Shah, James Antoney, Suk Woo Kang, Andrew C. Warden, Carol J. Hartley, Hadi Nazem-Bokaee, Colin J. Jackson, Colin Scott
Publikováno v:
Catalysts, Vol 9, Iss 10, p 868 (2019)
The asymmetric reduction of enoates, imines and ketones are among the most important reactions in biocatalysis. These reactions are routinely conducted using enzymes that use nicotinamide cofactors as reductants. The deazaflavin cofactor F420 also ha
Externí odkaz:
https://doaj.org/article/cd7f042e816c48f4a8971d75cad09ceb
Autor:
Suk Woo Kang, James Antoney, Rebecca L. Frkic, David W. Lupton, Robert Speight, Colin Scott, Colin J. Jackson
Publikováno v:
Biochemistry. 62:873-891
Publikováno v:
ChemBioChem. 24
Ene-reductases from the Flavin/Deazaflavin Oxidoreductase (FDOR) family have potential value in biocatalysis as they typically exhibit complementary stereoselectivity to the widely utilized Old Yellow Enzyme (OYE) family, yet they are comparatively p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68fc38c3c53082c9ff7648818de9bc45
https://doi.org/10.1101/2023.02.21.529347
https://doi.org/10.1101/2023.02.21.529347
Autor:
James Antoney, Stephanie Kainrath, F. Hafna Ahmed, Suk Woo Kang, Emily R. R. Mackie, Tatiana P. Soares da Costa, Colin J. Jackson, Harald Janovjak
Protein-protein interactions (PPIs) mediate many fundamental cellular processes and their control through optically or chemically responsive protein domains has a profound impact on basic research and some clinical applications. Most available chemog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6334540581e550e838a8f9be7a9de948
https://doi.org/10.1101/2022.11.07.515376
https://doi.org/10.1101/2022.11.07.515376
The stereoselective reduction of alkenes conjugated to electron-withdrawing groups by ene-reductases has been extensively applied to the commercial preparation of fine chemicals. Although several different enzyme families are known to possess ene-red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9335a60cb154b7c50b9ff2790155c541
https://doi.org/10.1101/2022.11.05.515281
https://doi.org/10.1101/2022.11.05.515281
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
The deazaflavin cofactor F420 is a low-potential, two-electron redox cofactor produced by some Archaea and Eubacteria that is involved in methanogenesis and methanotrophy, antibiotic biosynthesis, and xenobiotic metabolism. However, it is not produce