Zobrazeno 1 - 4
of 4
pro vyhledávání: '"James Andrew Lumley"'
Publikováno v:
Journal of Chemical Information and Modeling. 60:4757-4771
Matched Molecular Pairs (MMP) analysis is a well-established technique for Structure Activity and Property Analysis (SAR and SPR). Summarizing multiple MMPs that describe the same structural change into a single chemical transform can be a powerful t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb5736bb04c102db421f3462284618f
https://doi.org/10.1021/acs.jcim.0c00583
https://doi.org/10.1021/acs.jcim.0c00583
Autor:
Gary Sharman, Carlos Cobas, Michael Goebel, Thomas Wilkin, James Andrew Lumley, Matthew Hirst
Publikováno v:
SLAS Discovery. 25:950-956
Adequate characterization of chemical entities made for biological screening in the drug discovery context is critical. Incorrectly characterized structures lead to mistakes in the interpretation of structure-activity relationships and confuse an alr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95ac3e414594a5ff8d82a41528a3b5a
https://doi.org/10.1177/2472555220907091
https://doi.org/10.1177/2472555220907091
Publikováno v:
Artificial Intelligence in Drug Design ISBN: 9781071617861
Matched Molecular Pair Analysis (MMP) is a very important tool during the lead optimization stage in drug discovery. The usefulness of this tool in the lead optimization stage has been discussed in several peer-reviewed articles. The application of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72fb70228e2c944343276f4610e5e32e
https://doi.org/10.1007/978-1-0716-1787-8_23
https://doi.org/10.1007/978-1-0716-1787-8_23
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2390
Matched Molecular Pair Analysis (MMP) is a very important tool during the lead optimization stage in drug discovery. The usefulness of this tool in the lead optimization stage has been discussed in several peer-reviewed articles. The application of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0738ce0f14ccc22da62d84a68e8a92b1
https://pubmed.ncbi.nlm.nih.gov/34731485
https://pubmed.ncbi.nlm.nih.gov/34731485