Zobrazeno 1 - 6
of 6
pro vyhledávání: '"James Alex Tyrrell"'
Publikováno v:
The FASEB Journal. 26
Autor:
Janet M. Tse, Rakesh K. Jain, Gang Cheng, James Alex Tyrrell, Lance L. Munn, Sarah A. Wilcox-Adelman
Publikováno v:
The FASEB Journal. 24
Publikováno v:
The FASEB Journal. 24
Autor:
Daniel Fuja, James Alex Tyrrell, Rakesh K. Jain, Nyall London, Walid S. Kamoun, Emmanuelle di Tomaso, James J. Logie, Lance L. Munn
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5123 (2009)
PLoS ONE
PLoS ONE
Background: Recent clinical trials of VEGF inhibitors have shown promise in the treatment of recurrent glioblastomas (GBM). However, the survival benefit is usually short-lived as tumors escape anti-VEGF therapies. Here we tested the hypothesis that
Autor:
Patrick Au, David T. Scadden, Rakesh K. Jain, Dai Fukumura, Laurence Daheron, James Alex Tyrrell, Kenneth S. Cohen, Dan G. Duda, Ryan M. Lanning
Publikováno v:
Blood. 111(3)
Tissue engineering requires formation of a de novo stable vascular network. Because of their ability to proliferate, differentiate into endothelial cells, and form new vessels, blood-derived endothelial progenitor cells (EPCs) are attractive source o
Autor:
James Alex Tyrrell, Sergey V. Kozin, Rakesh K. Jain, William C. Sessa, Leo E. Gerweck, Kosuke Tsukada, Satoshi Kashiwagi, Junichi Miyazaki, Dai Fukumura, Lei Xu
Publikováno v:
Nature medicine. 14(3)
Normalization of tumor vasculature is an emerging strategy to improve cytotoxic therapies. Here we show that eliminating nitric oxide (NO) production from tumor cells via neuronal NO synthase silencing or inhibition establishes perivascular gradients