Zobrazeno 1 - 10
of 277
pro vyhledávání: '"James A. Walton"'
Autor:
Jennifer A. Liu, Jacob R. Bumgarner, William H. Walker, O. Hecmarie Meléndez-Fernández, James C. Walton, A. Courtney DeVries, Randy J. Nelson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Disrupted or atypical light–dark cycles disrupts synchronization of endogenous circadian clocks to the external environment; extensive circadian rhythm desynchrony promotes adverse health outcomes. Previous studies suggest that disrupted c
Externí odkaz:
https://doaj.org/article/3db26f7f09194bedbfbc8e4e4694b50a
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Despite its demonstrated biological significance, time of day is a broadly overlooked biological variable in preclinical and clinical studies. How time of day affects the influence of peripheral tumors on central (brain) function remains uns
Externí odkaz:
https://doaj.org/article/d2c857e643df4dd4a16fa6dcb936c265
Publikováno v:
Applied Sciences, Vol 14, Iss 7, p 2945 (2024)
Neuroscience and biological evidence emphasizes the profound influence of natural light on human health, offering benefits such as reducing fatigue, heightened alertness in healthcare providers, and improving patient outcomes. The objective of this r
Externí odkaz:
https://doaj.org/article/ac17dd3f99374e96a21df38bdd2b8e35
Autor:
Jacob R. Bumgarner, William H. Walker, II, Dominic D. Quintana, Rhett C. White, Alexandra A. Richmond, O. Hecmarie Meléndez-Fernández, Jennifer A. Liu, Darius D. Becker-Krail, James C. Walton, James W. Simpkins, A. Courtney DeVries, Randy J. Nelson
Publikováno v:
iScience, Vol 26, Iss 7, Pp 106996- (2023)
Summary: The structure and function of the cardiovascular system are modulated across the day by circadian rhythms, making this system susceptible to circadian rhythm disruption. Recent evidence demonstrated that short-term exposure to a pervasive ci
Externí odkaz:
https://doaj.org/article/ed91bee29496415f9073751292477765
Autor:
Randy J. Nelson, Jacob R. Bumgarner, Jennifer A. Liu, Jharnae A. Love, O. Hecmarie Meléndez-Fernández, Darius D. Becker-Krail, William H. Walker, James C. Walton, A. Courtney DeVries, Brian J. Prendergast
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background Circadian rhythms are important for all aspects of biology; virtually every aspect of biological function varies according to time of day. Although this is well known, variation across the day is also often ignored in the design a
Externí odkaz:
https://doaj.org/article/0fa73d5fe946415ab0e20c1d9c69e0a0
Autor:
James C. Walton, Randy J. Nelson
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1169 (2023)
Circadian rhythms are ubiquitous endogenous rhythms with a period of approximately twenty-four hours [...]
Externí odkaz:
https://doaj.org/article/bc0cb511711940e186e531486dd3979b
Autor:
William H. Walker, Samuel A. Sprowls, Jacob R. Bumgarner, Jennifer A. Liu, O. Hecmarie Meléndez-Fernández, James C. Walton, Paul R. Lockman, A. Courtney DeVries, Randy J. Nelson
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Chemotherapy is more effective in the treatment of peripheral tumors than brain metastases, likely reflecting the reduced ability of chemotherapy to cross the blood-brain barrier (BBB) and blood-tumor barrier at efficacious concentrations. Recent stu
Externí odkaz:
https://doaj.org/article/c4e732123d984230b67d1bf131feb837
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Several endogenous and exogenous factors interact to influence stroke occurrence, in turn contributing to discernable daily distribution patterns in the frequency and severity of cerebrovascular events. Specifically, strokes that occur during the mor
Externí odkaz:
https://doaj.org/article/42030d9d0397450799c4a43426579a85
Autor:
Benjamin W. Blonder, Philip G. Brodrick, K. Dana Chadwick, Erin Carroll, Roxanne M. Cruz‐de Hoyos, Moisés Expósito‐Alonso, Shannon Hateley, Minkyu Moon, Courtenay A. Ray, Hoang Tran, James A. Walton
Publikováno v:
New Phytologist. 238:2313-2328
Autor:
Atreyee Mishra, Karrera Y. Djoko, Yi-Hsuan Lee, Rianne M. Lord, Grace Kaul, Abdul Akhir, Deepanshi Saxena, Sidharth Chopra, James W. Walton
Publikováno v:
Organic & Biomolecular Chemistry, 2023, Vol.21(12), pp.2539-2544 [Peer Reviewed Journal]
Copper Pyrithione, [Cu(PyS)2] has shown excellent biological activity against cancer cells and bacterial cells, however, it has extremely low aqueous solubility, limiting its applicability. Herein, we report a series of PEG-substituted pyrithione cop