Zobrazeno 1 - 10
of 1 314
pro vyhledávání: '"James A. Walsh"'
Autor:
KM Rifat Faysal, James C Walsh, Nadine Renner, Chantal L Márquez, Vaibhav B Shah, Andrew J Tuckwell, Michelle P Christie, Michael W Parker, Stuart G Turville, Greg J Towers, Leo C James, David A Jacques, Till Böcking
Publikováno v:
eLife, Vol 13 (2024)
The HIV-1 capsid has emerged as a tractable target for antiretroviral therapy. Lenacapavir, developed by Gilead Sciences, is the first capsid-targeting drug approved for medical use. Here, we investigate the effect of lenacapavir on HIV capsid stabil
Externí odkaz:
https://doaj.org/article/08ba42401fe84baebde255dedc84b832
Publikováno v:
European Journal of Psychotraumatology, Vol 14, Iss 2 (2023)
ABSTRACTBackground: Persons displaced by conflict often consider returning to their area of origin. Lack of reliable information about conditions in the area of origin makes this decision more difficult. Displaced persons address this by seeking info
Externí odkaz:
https://doaj.org/article/2629052abf44465f888bcd94e7bd0566
Autor:
Kevin McCarthy, Eamon Laird, Aisling M. O'Halloran, Cathal Walsh, Martin Healy, Annette L. Fitzpatrick, James B. Walsh, Belinda Hernández, Padraic Fallon, Anne M. Molloy, Rose Anne Kenny
Publikováno v:
EClinicalMedicine, Vol 53, Iss , Pp 101654- (2022)
Summary: Background: It is hypothesized that vitamin D contributes to the aetiology of type 2 diabetes mellitus (diabetes). This study's objective was to examine the relationships between baseline vitamin D status (as measured by plasma 25-hydroxyvit
Externí odkaz:
https://doaj.org/article/cd7f862cb96a49bbb72994ed1a615f18
Autor:
Conall McGuinness, James C Walsh, Charles Bayly-Jones, Michelle A Dunstone, Michelle P Christie, Craig J Morton, Michael W Parker, Till Böcking
Publikováno v:
eLife, Vol 11 (2022)
The cholesterol-dependent cytolysin perfringolysin O (PFO) is secreted by Clostridium perfringens as a bacterial virulence factor able to form giant ring-shaped pores that perforate and ultimately lyse mammalian cell membranes. To resolve the kinetic
Externí odkaz:
https://doaj.org/article/9c52c20469604be898a9fcf4065fd2d3
Autor:
James Bernard Walsh, Daniel M. McCartney, Éamon Laird, Kevin McCarroll, Declan G. Byrne, Martin Healy, Paula M. O’Shea, Rose Anne Kenny, John L. Faul
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
While a low vitamin D state has been associated with an increased risk of infection by SARS-CoV-2 in addition to an increased severity of COVID-19 disease, a causal role is not yet established. Here, we review the evidence relating to i) vitamin D an
Externí odkaz:
https://doaj.org/article/2709d89b3a0a4ea19fc481f571d99ecb
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Although the Cold Atmospheric Plasma (CAP) technology proved promising for inactivation of biofilms present on abiotic food contact surfaces, more research is required to examine the behavior of the CAP surviving biofilm-associated cells. It was ther
Externí odkaz:
https://doaj.org/article/f43b0ae7ede4426c9ba6859926e4e660
Autor:
Helena Scully, Eamon Laird, Martin Healy, Vivion Crowley, James Bernard Walsh, Kevin McCarroll
Publikováno v:
Journal of Nutritional Science, Vol 11 (2022)
Vitamin D is essential for bone and muscle health with adequate status in childhood crucial for normal skeletal development. We aimed to investigate vitamin D status in a convenience sample (n = 1226) of Irish children (aged 1–17 years) who had ser
Externí odkaz:
https://doaj.org/article/8bfa7b9f685c48518eafb1450d4a0b25
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0247589 (2021)
Cold plasma generated in air at atmospheric pressure is an extremely effective antimicrobial agent, with proven efficacy against clinically relevant bacterial biofilms. The specific mode of bacterial inactivation is highly dependent upon the configur
Externí odkaz:
https://doaj.org/article/21ef495701be43fbb16a8905befb1fe7
Publikováno v:
Proceedings of the Nutrition Society. :1-15
Vitamin D is crucial for musculoskeletal health, with evidence suggesting non-skeletal benefits. Cutaneous vitamin D synthesis is limited in Ireland due to its northern latitude (52–55°N) and the population is dependent on dietary sources, yet int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7f959371ec835fa33d47d87c33c03e0
https://doi.org/10.1017/s0029665123002185
https://doi.org/10.1017/s0029665123002185
Autor:
Helena Scully, Eamon J. Laird, Martin Healy, Vivion Crowley, James Bernard Walsh, Kevin McCarroll
Publikováno v:
British Journal of Nutrition. :1-11
Vitamin D deficiency is common in Irish adults, though there is limited research on its determinants, knowledge of vitamin D or indications for testing. We aimed to explore the determinants of vitamin D status in adults and examine knowledge and reas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f04d7963496ba5f84ae4f7fce588ee3
https://doi.org/10.1017/s0007114523000168
https://doi.org/10.1017/s0007114523000168