Zobrazeno 1 - 10
of 11
pro vyhledávání: '"James A. Rybski"'
Autor:
James A. Rybski, Rik J. Scheper, Thomas M. Grogan, Catherine M. Spier, Ronald S. Weinstein, Sydney E. Salmon, William S. Dalton, Monica Matzner
Publikováno v:
Blood. 81:490-495
Multidrug-resistant (MDR) myeloma patients failing chemotherapy may express P-glycoprotein (PGP), which serves as an efflux pump protecting the neoplastic cells. Unknown is whether PGP expression might relate to prior cytotoxic drug exposure. To addr
Autor:
Thomas M. Grogan, Thomas P. Miller, D P Kerrigan, James A. Rybski, Donald J. Slymen, Catherine M. Spier, Scott M. Lippman, Lynne Richter, Catherine S. Rangel
Publikováno v:
Journal of Clinical Oncology. 8:986-993
The prognostic importance of immunobiologic factors in diffuse large-cell lymphoma (DLCL) is studied in 105 consecutive DLCL patients. Multivariate results using the Cox proportional hazards model clearly indicate that the Ki-67 index (P = .002), a m
Autor:
Catherine S. Rangel, Monika Matzner, Guillermo Gonzales, James A. Rybski, Catherine M. Spier, Thomas P. Miller, Thomas M. Grogan, Catherine P. Leith
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 10(8)
PURPOSE AND METHODS Diffuse small cleaved-cell lymphoma (DSCL) is a relatively uncommon non-hodgkin's lymphoma (NHL) in the United States and has not been the subject of recent in-depth study of factors predictive of outcome. It is unique among the N
Autor:
Henricus J. Broxterman, Lynne Richter, Thomas M. Grogan, Jenai M. Kailey, James A. Rybski, Herbert M. Pinedo, Rik J. Scheper, William S. Dalton, Sydney E. Salmon
Publikováno v:
Blood. 73:747-752
Using several multiple drug-resistant human myeloma cell lines as standards, we developed an immunohistochemical staining technique and means of quantitating P-glycoprotein in individual myeloma cells. The level of staining intensity for P-glycoprote
Autor:
Arthur B. Raitano, Philip Scuderi, P.S. Meltzer, James A. Rybski, James D. Liddil, Robert T. Dorr, Paul R. Finley
Publikováno v:
European Journal of Immunology. 19:939-942
The secretion of tumor necrosis factor (TNF) by human peripheral blood mononuclear cells was suppressed by either whole human plasma alpha-globulins or purified alpha 1-acid-glycoprotein, alpha 1-antitrypsin and alpha 2-macroglobulin in a concentrati
Publikováno v:
European Journal of Biochemistry. 92:325-331
The addition of putrescine, spermidine, or spermine, to cultures of Physarum polycephalum rapidly reduced the activity of ornithine decarboxylase, with maximal inhibition, 80-90%, occurring after 90 min. This response was not due to a decrease in enz
Autor:
Thomas P. Miller, Catherine S. Rangel, Scott M. Lippman, Lynne Richter, Catherine M. Spier, Thomas M. Grogan, James A. Rybski, Donald J. Slymen
Publikováno v:
Blood. 71:1157-1160
To assess the prognostic significance of the growth fraction in diffuse large cell lymphoma (DLCL), we studied 105 DLCL patients with the monoclonal antibody Ki-67 applied to frozen tissue sections. Ki-67 detects a nuclear antigen associated with cel
Publikováno v:
Journal of Investigative Dermatology. (5):892-897
The effect of dietary canthaxanthin, retinyl palmitate, or their combination on the tumor-infiltrating T-lymphocyte response (T-TIL) in de novo murine ultraviolet type B irradiation-induced tumors was investigated to elucidate potential mechanisms of
Publikováno v:
Journal of leukocyte biology. 45(1)
Macrophages are important positive and negative regulators of both primary and secondary antibody responses, and their activity may, in turn, be controlled by soluble mediators secreted by other cells. Fibronectin is a 440,000 dalton normal constitue
Publikováno v:
Journal of leukocyte biology. 45(3)
The effect of beta-carotene on cytokine production by human peripheral blood leukocytes was tested. Beta-carotene stimulated the secretion of a novel cytotoxic cytokine when peripheral blood cells were exposed to carotenoid concentrations between 10-