Zobrazeno 1 - 10
of 20
pro vyhledávání: '"James A. Profitt"'
Publikováno v:
Analytical Chemistry. 78:1769-1773
Amplification of the electrochemical impedance and capacitance signals in a biosensor is demonstrated for the model fluorescein/anti-fluorescein system. Following immobilization of fluorescein onto Au through formation of a self-assembled monolayer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51ef9b6aeb2893383d90c0bea0a5c9aa
https://doi.org/10.1021/ac051113+
https://doi.org/10.1021/ac051113+
Autor:
Hai Hang Kuo, James A. Profitt, Klaus Kadel, Ronald G Sommer, Gert Blankenstein, Thomas Willms, Ralf-Peter Peters, Michael J. Pugia, Lloyd S. Schulman
Publikováno v:
Clinical Chemistry. 51:1923-1932
Background: Use of microfluidics in point-of-care testing (POCT) will require on-board fluidics, self-contained reagents, and multistep reactions, all at a low cost. Disposable microchips were studied as a potential POCT platform.Methods: Micron-size
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6808208b775ac851cde9d3da73a6e51c
https://doi.org/10.1373/clinchem.2005.052498
https://doi.org/10.1373/clinchem.2005.052498
Autor:
Larry Clark, Todd K. Cast, Michael J. Pugia, James A. Profitt, David J. Newman, Lucia D'Mello, John A. Lott
Publikováno v:
Clinica Chimica Acta. 326:177-183
Background : Testing of urines with dipsticks for proteinuria, glycosuria, etc., is common practice. A deficiency with currently available dipsticks is their lack of chemical sensitivity and underestimation of low-molecular-weight proteins such as li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be91aa6214930062c902c2a20d0d018
https://doi.org/10.1016/s0009-8981(02)00304-2
https://doi.org/10.1016/s0009-8981(02)00304-2
Publikováno v:
Analytical chemistry. 78(6)
Amplification of the electrochemical impedance and capacitance signals in a biosensor is demonstrated for the model fluorescein/anti-fluorescein system. Following immobilization of fluorescein onto Au through formation of a self-assembled monolayer,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b05293f800bccaf7acaed99e5f842d96
https://pubmed.ncbi.nlm.nih.gov/16536410
https://pubmed.ncbi.nlm.nih.gov/16536410
We developed a dye‐binding method for albumin in urine based on bis (3′,3″‐diiodo‐4′4″‐dihydroxy‐5′5″‐dinitrophenyl)‐3,4,5,6‐tetrabromosulfonphthalein (DIDNTB), a dye that has a higher chemical sensitivity and specificity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e18e9c85813e9f2b1706de3da6c6adc
https://europepmc.org/articles/PMC6807896/
https://europepmc.org/articles/PMC6807896/
Publikováno v:
Synthetic Communications. 5:457-460
Many antibiotics of the anthracycline family1 possess structures for which 3-methoxyphthalic anhydride (1) would be a suitable synthon2 in a total synthesis. A classic synthesis of (1) has employed 3-nitrophthalic acid3 but, in our hands, proceeded i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb22d8597e90eff5e27817b08b1f7803
https://doi.org/10.1080/00397917508065581
https://doi.org/10.1080/00397917508065581
Autor:
T. C. Spaulding, Harry M. Geyer, James A. Profitt, Vernon B. Anderson, Helen H. Ong, J. C. Wilker
Publikováno v:
Journal of Medicinal Chemistry. 25:1150-1153
A series of [[(alkylamino)ethyl]thio]dibenz[b,f]oxepins (I) and their 10,11-dihydro derivatives (II) was synthesized and subjected to broad analgesic/CNS screening. Several analogues of both types, carrying small N-substituents and frequently a nucle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af408de91cb0d1ed439f4fda80cb6441
https://doi.org/10.1021/jm00352a010
https://doi.org/10.1021/jm00352a010
Autor:
Helen H. Ong, Hansjoerg Kruse, Harry M. Geyer, James A. Profitt, Anderson V Brian, J. C. Wilker
Publikováno v:
Journal of Medicinal Chemistry. 24:74-79
A series of 3-aryl-1,3-dihydrospiro[benzo[c]thiophene-1,4'-piperidine] derivatives was synthesized and evaluated pharmacologically for potential psychotropic activity. Potent antidepressant-like activity was noted throughout the series, as assessed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40fc3af0eb2f778f77cae181d7cc43e8
https://doi.org/10.1021/jm00133a016
https://doi.org/10.1021/jm00133a016
Publikováno v:
Journal of Heterocyclic Chemistry. 20:867-870
Several (dihydrobenzoxathiinyloxy)acetic acids have been prepared as potential antihypertensive agents. The dihydrobenzoxathiin ring system was constructed via an intramolecular alkoxide displacement reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34c39381878ac1f0dfccd1f582c70a29
https://doi.org/10.1002/jhet.5570200406
https://doi.org/10.1002/jhet.5570200406
Publikováno v:
Journal of Medicinal Chemistry. 22:834-839
A series of 10,11-dihydro-11-oxospiro[dibenz[b,f]oxepin-10,4'-piperdine] derivatives (II) was synthesized and evaluated for analgesic activity in the phenylquinone writhing assay (PQW) and the tail-flick test in mice. Preliminary structure-activity c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaac6c2b86d00c65f9371e4eb27d1930
https://doi.org/10.1021/jm00193a016
https://doi.org/10.1021/jm00193a016