Zobrazeno 1 - 10
of 109
pro vyhledávání: '"James A. Merritt"'
Autor:
Lindsay B. Baker, Michal Ozga, James R. Merritt, Shelby Alfred, Peter John D. De Chavez, J. Matthew Hinkley
Publikováno v:
Physiological Reports, Vol 12, Iss 18, Pp n/a-n/a (2024)
Abstract The purpose of this study was to determine the effect of hydration status on the change in sweat sodium (Na+), chloride (Cl−), and potassium (K+) concentrations during exercise‐heat stress. Fifteen subjects (Six female, nine male; 29 ±
Externí odkaz:
https://doaj.org/article/1c70cbad4c22404abdb18f8ecc327d73
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Due to growing interest in the investigation of exercise induced sweat biomarkers to assess an individual’s health and the increasing prevalence of tattoos in the world’s population, investigators sought to determine whether local sweat
Externí odkaz:
https://doaj.org/article/499e85971c82468e8f4a6089a23b9f0d
Autor:
E Hope Weissler, Amanda Stebbins, Lisa Wruck, Daniel Muñoz, Kamal Gupta, Saket Girotra, Jeff Whittle, Catherine P Benziger, Tamar S Polonsky, Steven M Bradley, Bradley G Hammill, James G Merritt, Doris N Zemon, Adrian F Hernandez, W Schuyler Jones
Publikováno v:
Vascular Medicine. 28:122-130
Background: We aimed to understand the effects of aspirin dose on outcomes in patients with peripheral artery disease (PAD) as well as their participation in a pragmatic randomized controlled trial. Methods: In a subanalysis of the Aspirin Dosing: A
Autor:
Russell L. Rothman, Douglas S. Bell, Sunil Kripalani, Sandeep Jain, Kenneth C. Gregoire, Madelaine Faulkner Modrow, W. Schuyler Jones, Matthew T. Roe, James G. Merritt, Richard N. Re, Thomas E. McCormick, Rachel Hess, Eileen M. Handberg, Ythan H. Goldberg, Daniel Muñoz, Abel N. Kho, Michael J. Pencina, Anuradha Paranjape, Gregory M. Marcus, Daniel E. Ford, David L. Crenshaw, Desiree R. Davidson, Li Zhou, Guillaume Marquis-Gravel, Lisa M. Wruck, Faraz S. Ahmad, James C. McClay, Catherine P. Benziger, Jeffrey J. VanWormer, Rainu Kaushal, Elizabeth Shenkman, Jeff Whittle, Lesley H. Curtis, Oana A. Sandu, Laura G. Qualls, Lemuel R. Waitman, Thomas W Carton, Tamar S. Polonsky, Kirk U. Knowlton, Darren A. DeWalt, Elliott M. Antman, James R. Campbell, Linda S. Brown, Véronique L. Roger, Jennifer L. Kraschnewski, R. David Anderson, Doris N. Zemon, Debra F. Harris, Holly Robertson, Kevin Haynes, Elizabeth Nauman, Kevin Edgley, Adrian F. Hernandez, Gregg C. Fonarow, Saket Girotra, Carl J. Pepine, Frederick A. Masoudi, Robert A. Harrington, Steven M. Bradley, Brittney R. Manning, Dan J. Fintel, Kamal Gupta, Jacqueline D. Alikhaani, Amber G. Sharlow, Kathleen M. McTigue, Lisa G. Berdan, Peter Farrehi, Danielle Riley, Mark B. Effron, Bradley G. Hammill, Hillary Mulder
Publikováno v:
N Engl J Med
The New England journal of medicine, vol 384, iss 21
The New England journal of medicine, vol 384, iss 21
BACKGROUND: The appropriate dose of aspirin to lower the risk of death, myocardial infarction, and stroke and to minimize major bleeding in patients with established atherosclerotic cardiovascular disease is a subject of controversy. METHODS: Using a
Autor:
Nicholas J. Lodge, John E. Macor, Matthew A. Seager, Samuel Gerritz, Shaun Langdon, Robert Zaczek, Joanne J. Bronson, Alda Fernandes, Karen Heman, James R. Merritt, Yuan Tian, Ryan Westphal, Yang Hong, Annapurna Pendri, Lizbeth Gallagher, Trevor Wojcik, Chongwu Zhang, Yu-Wen Li, Thaddeus F. Molski
Publikováno v:
Neuropharmacology. 102:121-135
Phosphodiesterase 10A (PDE10A) inhibitors increase the functionality of striatal medium spiny neurons and produce antipsychotic-like effects in rodents by blocking PDE10A mediated hydrolysis of cAMP and/or cGMP. In the current study, we characterized
Abstract 4548: The chemokine receptor CCR1 is involved in microglia stimulated glioblastoma invasion
Autor:
Diana Habib, Poornema Ramasundaram, Neshama Fournier, Gregory Marshall, James Robert Merritt, Keia Smith, Danielle S. Hamilton, Salvatore J. Coniglio
Publikováno v:
Cancer Research. 79:4548-4548
Glioblastoma Multiforme (GBM) is the most aggressive form of adult brain tumor with a median survival time of twelve months. GBM is highly resistant to conventional therapy which includes surgical resection of the tumor, radiation treatment and chemo
Autor:
Jill Van Wart Hood, Abner M. Mhashilkar, Yu-An Zhang, Elizabeth A. Grimm, Keith Coffee, George J. Netto, Dawn Rich, Alex W. Tong, Suhendan Ekmekcioglu, Casey Cunningham, Dan Su, John Nemunaitis, Karen Parker, Neil Senzer, James A. Merritt, Sunil Chada, Rajagopal Ramesh
Publikováno v:
Molecular Therapy. 11(1):160-172
The mda-7 gene (approved gene symbol IL24) is a novel tumor suppressor gene with tumor-apoptotic and immune-activating properties. We completed a Phase I dose-escalation clinical trial, in which a nonreplicating adenoviral construct expressing the md
Autor:
Sasha Vukelja, Casey Cunningham, Alex W. Tong, Yuan Zhang, Neil Senzer, Jill Van Wart Hood, Karen Parker, Abner M. Mhashilkar, Keith Coffee, John Nemunaitis, James A. Merritt, Don Richards, Sunil Chada
Publikováno v:
Molecular Therapy. 11:149-159
The melanoma differentiation-associated gene-7 (mda-7; approved gene symbol IL24) is a tumor suppressor gene whose expression induces selective apoptosis in tumor cells. To characterize the safety and biologic activity of mda-7 gene transfer, we cond
Autor:
Guosheng Liu, John M. Norman, Antonio Donato Nobre, Andrew Grose, Celso von Randow, Jiujing Gu, M.J. Waterloo, José A. Marengo, Pedro Leite da Silva Dias, Antonio O. Manzi, James D. Merritt, Alessandro Araújo, Harry J. Cooper, Eric A. Smith, Paulo Jorge de Oliveira
Publikováno v:
Journal of Applied Meteorology. 43:870-886
In this first part of a two-part investigation, large-scale Geostationary Operational Environmental Satellite (GOES) analyses over the Amazonia region have been carried out for March and October of 1999 to provide detailed information on surface radi
Autor:
Christopher G. Wood, Kim Anh Do, E. Hossan, L. Clifton Stephens, Timothy J. McDonnell, Robert B. Evans, Christopher J. Logothetis, Xuemei Wang, James A. Merritt, Shawn Brisbay, Cindy Soto, Marc G. Jacobson, Patricia Troncoso, Curtis A. Pettaway, Karen Parker, Mitchell S. Steiner, Louis L. Pisters
Publikováno v:
Clinical Cancer Research. 10:2587-2593
Purpose: INGN 201 (Ad-p53) is a replication-defective adenoviral vector that encodes a wild-type p53 gene driven by the cytomegalovirus promoter. INGN 201 has been shown to have antitumoral activity against human prostate cancer cell lines. This stud