Zobrazeno 1 - 7
of 7
pro vyhledávání: '"James A. Lofgren"'
Publikováno v:
Journal of Immunological Methods. 396:44-55
As with other protein therapeutics, trebananib (AMG 386), an investigational peptide Fc-fusion protein ("peptibody") that inhibits angiogenesis by neutralizing the interaction of angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2) with the Tie2 receptor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a62e8b172611a7c567e3134ea6bf400
https://doi.org/10.1016/j.jim.2013.07.010
https://doi.org/10.1016/j.jim.2013.07.010
Autor:
Christina M. Abbott, James A. Lofgren, Sripriya Dhandapani, Jason J. Pennucci, Daniel T. Mytych, Steven J. Swanson, Arunan Kaliyaperumal, Michael C. Mullenix
Publikováno v:
The Journal of Immunology. 178:7467-7472
Evaluation of the immunogenicity of panitumumab, a fully human anti-epidermal growth factor receptor mAb approved for use in colorectal cancer patients, led to the development of two separate immunoassays for the detection of anti-panitumumab Abs. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c858ae84e13cdc11ee7b5cfc72940cf7
https://doi.org/10.4049/jimmunol.178.11.7467
https://doi.org/10.4049/jimmunol.178.11.7467
Autor:
James R. Lofgren
Publikováno v:
Sunflower Technology and Production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0258dc2c2b527c84cd7431a2378ecc7e
https://doi.org/10.2134/agronmonogr19.c14
https://doi.org/10.2134/agronmonogr19.c14
Publikováno v:
Biotechnology and Bioengineering. 60:589-595
Under some cell culture conditions, recombinant glycoprotein therapeutics expressed in Chinese hamster ovary (CHO) cells lose sialic acid during the course of the culture (Sliwkowski et al., 1992; Munzert et al., 1996). A soluble sialidase of CHO cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc15b51bc7b84e2934cc88a82b27e708
https://doi.org/10.1002/(sici)1097-0290(19981205)60:5<589::aid-bit9>3.0.co
https://doi.org/10.1002/(sici)1097-0290(19981205)60:5<589::aid-bit9>3.0.co
Publikováno v:
Journal of immunological methods. 308(1-2)
Neutralizing antibodies against therapeutic proteins can be potentially harmful if the antibody blocks not only the therapeutic activities of the therapeutic protein but also the normal functions of the endogenous counterpart. Detection of the neutra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb8a90d45ac2e42829a5d35eaeedb5d
https://pubmed.ncbi.nlm.nih.gov/16356511
https://pubmed.ncbi.nlm.nih.gov/16356511
Publikováno v:
Journal of immunoassay. 12(4)
A goat antiserum to purified recombinant human activin A (rhAct-A), a dimer formed by two beta A-subunits of inhibin, has been produced. The immunoreactivity of the antiserum has been evaluated in an antigen coated enzyme-linked immunosorbent assay,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d5edc47a67bf96eabb0303a616e836
https://pubmed.ncbi.nlm.nih.gov/1806589
https://pubmed.ncbi.nlm.nih.gov/1806589