Zobrazeno 1 - 10
of 49
pro vyhledávání: '"James A. Loehr"'
Autor:
Lathan Lucas, Larissa Nitschke, Brandon Nguyen, James A. Loehr, George G. Rodney, Thomas A. Cooper
Publikováno v:
iScience, Vol 27, Iss 11, Pp 111104- (2024)
Summary: Skeletal muscle cells (myofibers) are elongated non-mitotic, multinucleated syncytia that have adapted a microtubule lattice. Microtubule-associated proteins (MAPs) play roles in regulating microtubule architecture. The most abundant MAP in
Externí odkaz:
https://doaj.org/article/b97167ad0f6049e7a56278c345d0f1e0
Publikováno v:
Frontiers in Physiology, Vol 5 (2015)
Elevated concentrations of sphingomyelinase (SMase) have been detected in a variety of diseases. SMase has been shown to increase muscle derived oxidants and decrease skeletal muscle force; however, the sub-cellular site of oxidant production has not
Externí odkaz:
https://doaj.org/article/432a746055a44c21b0acb19b41f726c9
Autor:
James Anthony Loehr, Shang Wang, Tanya R Cully, Rituraj Pal, Irina V Larina, Kirill V Larin, George G Rodney
Publikováno v:
eLife, Vol 11 (2022)
Externí odkaz:
https://doaj.org/article/0d8404561d0645fdad5e36648483aa2f
Autor:
James Anthony Loehr, Shang Wang, Tanya R Cully, Rituraj Pal, Irina V Larina, Kirill V Larin, George G Rodney
Publikováno v:
eLife, Vol 7 (2018)
Skeletal muscle from mdx mice is characterized by increased Nox2 ROS, altered microtubule network, increased muscle stiffness, and decreased muscle/respiratory function. While microtubule de-tyrosination has been suggested to increase stiffness and N
Externí odkaz:
https://doaj.org/article/9e36ae2446184f9694041650fe83a4b8
Autor:
Amy E Brinegar, Zheng Xia, James Anthony Loehr, Wei Li, George Gerald Rodney, Thomas A Cooper
Publikováno v:
eLife, Vol 6 (2017)
Postnatal development of skeletal muscle is a highly dynamic period of tissue remodeling. Here, we used RNA-seq to identify transcriptome changes from late embryonic to adult mouse muscle and demonstrate that alternative splicing developmental transi
Externí odkaz:
https://doaj.org/article/937ae9dfce8f43faa857a4d762c05add
Autor:
Gary R. Stinnett, George G. Rodney, Robia G. Pautler, Wesley T. Roten, Mayra Hernández-Rivera, Lon J. Wilson, James A. Loehr
Publikováno v:
The Journal of Physiology. 594:6395-6405
Key points Inhibiting Nox2 reactive oxygen species (ROS) production reduced in vivo calcium influx in dystrophic muscle. The lack of Nox2 ROS production protected against decreased in vivo muscle function in dystrophic mice. Manganese-enhanced magnet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e59d58745c2c5374514e6780c10f7099
https://doi.org/10.1113/jp272907
https://doi.org/10.1113/jp272907
Autor:
Rituraj Pal, Kirill V. Larin, James A. Loehr, Irina V. Larina, George G. Rodney, Shang Wang, Tanya R. Cully
Publikováno v:
eLife, Vol 7 (2018)
eLife. 2018. Vol. 7. P. e31732 (1-19)
eLife
eLife. 2018. Vol. 7. P. e31732 (1-19)
eLife
Skeletal muscle from mdx mice is characterized by increased Nox2 ROS, altered microtubule network, increased muscle stiffness, and decreased muscle/respiratory function. While microtubule de-tyrosination has been suggested to increase stiffness and N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e21d5867c205ace84f1e3b45e44aef7
https://pubmed.ncbi.nlm.nih.gov/36250696
https://pubmed.ncbi.nlm.nih.gov/36250696
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
Postnatal development of skeletal muscle is a highly dynamic period of tissue remodeling. Here we used RNA-seq to identify transcriptome changes from late embryonic to adult mouse muscle and demonstrate that alternative splicing developmental transit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e54a86f5e8a26a46df04aeb2c8738ea
