Zobrazeno 1 - 10
of 470
pro vyhledávání: '"James A. Harper"'
Autor:
James M. Harper
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7905 (2024)
Primary cell culture is a powerful model system to address fundamental questions about organismal physiology at the cellular level, especially for species that are difficult, or impossible, to study under natural or semi-natural conditions. Due to th
Externí odkaz:
https://doaj.org/article/6015c0cb37fd41648cf65f5a1bb10afc
Autor:
James M. Harper
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/cdf2943b814d4a779935f9eae6d08b44
Autor:
James M. Harper
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/7b83b7a7d6c64231812de30e2e1cf9c5
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Modern approaches for calculating electric field gradient (EFF) tensors in molecular solids rely upon plane-wave calculations employing periodic boundary conditions (PBC). In practice, models employing PBCs are limited to generalized gradient approxi
Externí odkaz:
https://doaj.org/article/695e17415a214b9fb0be0206d8d1297f
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The A chains of ADP-ribosylating toxins exploit Hsp90 for translocation into the host cytosol. Here, we hypothesize that cis proline residues play a key role in toxin recognition by Hsp90. Our model is largely derived from studies on the unusual inte
Externí odkaz:
https://doaj.org/article/30783fd7411e4a99a9f2c72235eaa0b1
Publikováno v:
OBM Geriatrics. :1-17
In the 1950’s Denham Harman proposed the Free Radical Theory of Aging whereby species lifespan and individual longevities are the consequence of free radical driven damage to biomolecules. This led to decades of research to ascertain the effect of
Autor:
Jacob T. Bryant, Matthew W. Logan, Zhihengyu Chen, Marcus Djokic, Daniel R. Cairnie, Demetrius A. Vazquez-Molina, A. Nijamudheen, Kyle R. Langlois, Michael J. Markley, Gisselle Pombar, Ashley A. Holland, Jonathan D. Caranto, James K. Harper, Amanda J. Morris, Jose L. Mendoza-Cortes, Titel Jurca, Karena W. Chapman, Fernando J. Uribe-Romo
Publikováno v:
Journal of the American Chemical Society. 145:4589-4600
Publikováno v:
Magnetic Resonance in Chemistry. 61:253-267
Autor:
Robert W. Wilkinson, Simon J. Dovedi, Ross Stewart, Viia Valge-Archer, Michelle Morrow, James A. Harper, Hazel Jones, Matthew McCourt, Brandon W. Higgs, Philip Brohawn, Jane Coates Ulrichsen, Amanda Watkins, Judith Anderton, Danielle Marcus, Luciano Pacelli, Stefanie Mullins, Rebecca Leyland, Miika J. Ahdesmaki, Danielle M. Greenawalt, Dennis Y.Q. Wang, Jens-Oliver Koopmann, Richard C.A. Sainson, John E. Prime, Suzanne I.S. Mosely
Murine syngeneic tumor models are critical to novel immuno-based therapy development, but the molecular and immunologic features of these models are still not clearly defined. The translational relevance of differences between the models is not fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adcb199105c771e6b82b33f00095d352
https://doi.org/10.1158/2326-6066.c.6548411.v1
https://doi.org/10.1158/2326-6066.c.6548411.v1
Autor:
Robert W. Wilkinson, Simon J. Dovedi, Ross Stewart, Viia Valge-Archer, Michelle Morrow, James A. Harper, Hazel Jones, Matthew McCourt, Brandon W. Higgs, Philip Brohawn, Jane Coates Ulrichsen, Amanda Watkins, Judith Anderton, Danielle Marcus, Luciano Pacelli, Stefanie Mullins, Rebecca Leyland, Miika J. Ahdesmaki, Danielle M. Greenawalt, Dennis Y.Q. Wang, Jens-Oliver Koopmann, Richard C.A. Sainson, John E. Prime, Suzanne I.S. Mosely
Supplementary Figure S1: Summary of experiments Supplementary Figure S2: Gating strategy Supplementary Figure S3:Profiling by array CGH, whole-exome and targeted sequencing Supplementary Figure S4: Comparison of mutational profiles of murine syngenei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f963acbe001e8dcef590d845d2ff257
https://doi.org/10.1158/2326-6066.22537352.v1
https://doi.org/10.1158/2326-6066.22537352.v1