Zobrazeno 1 - 10
of 24
pro vyhledávání: '"James A. Happe"'
Publikováno v:
Carcinogenesis. 13:621-627
The metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP), a heterocyclic amine carcinogen detected in cooked meats, was investigated in mice. In 3-methylcholanthrene-induced mice administered 0.1, 1.0 and 10 mg/kg [14C]PhIP (i.p.), u
Publikováno v:
Mutation research. 260(4)
A new heterocyclic amine mutagen was isolated from a dry-heated reaction of the natural meat components creatine, glutamic acid and glucose. Heating creatine and glutamic acid alone had only one seventh of the Ames/Salmonella mutagenic activity of th
Autor:
Nancy H. Shen, Mark G. Knize, James S. Felton, B.D. Andresen, F. T. Hatch, P.R. Lewis, James A. Happe
Publikováno v:
Carcinogenesis. 7:1081-1086
A new mutagenic compound has been isolated from ground beef which was fried at 300 degrees C for 5.5 min on each side. The new mutagen was purified using an aqueous acid extraction, XAD-2 adsorption-solvent elution, a series of preparative and analyt
Publikováno v:
Journal of Environmental Science and Health . Part A: Environmental Science and Engineering. 14:87-109
It was reported earlier that methylcobalamin (MeB‐12) plus K2PtCl6 or Na2PtCl6 under acidic conditions yields a single square planar Pt2+ species, MePtCl2‐ 3. A reaction between MeB‐12 and PtCl4 in...
Autor:
James S. Felton, Eva Övervik, Mark G. Knize, Jan-Åke Gustafsson, James A. Happe, Tore Midtvedt, Kenneth W. Turteltaub
Publikováno v:
Carcinogenesis. 10:1479-1484
The aromatic amine mutagen, [14C]2-amino-3,4-8-trimethyl-imidazo[4,5-f]quinoxaline (4,8-DiMeIQx), which is derived from cooked food, was administered to conventional and germ-free AGUS rats previously fed either a semi-synthetic diet containing the c
Autor:
James A. Happe, Alan K. Burnham
Publikováno v:
Fuel. 63:1353-1356
Aromaticities determined by 13 C n.m.r. are reported for five shale oil samples (Green River formation) prepared under widely different pyrolysis conditions. In the absence of high-pressure hydrogen, the total amount of aromatic carbon in the product
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 178:25-32
Two mutagens isolated from fried-beef patties were compared to a series of synthetic structural isomers of 2-aminodimethylimidazo[4,5-ƒ]quinoxaline (MeIQx) and 2-aminotrimethylimidao[4,5-ƒ]quinoxaline (DiMeIQx). Comparison by NMR spectrometry and H
Autor:
Raymond L. Ward, James A. Happe
Publikováno v:
The Journal of Physical Chemistry. 83:3457-3462
The interaction of Zn(II) with nucleotide triphosphates has been studied by /sup 35/Cl NMR and by /sup 1/H NMR. In 0.5 M NaCl solutions, enhanced /sup 35/Cl relaxation is produced by the metal ion in a Zn(II)-nucleotide triphosphate complex, Zn(NTP).
Publikováno v:
Polymer. 26:827-836
1H, 19F and 11B nuclear magnetic resonance studies are reported which characterize the complexes of boron trifluoride with monoethylamine and with piperidine, BF3:NH2C2H5 and BF3:NHC5H10, respectively. These complexes are used as catalysts for the cu
Publikováno v:
Journal of Environmental Science and Health . Part A: Environmental Science and Engineering. 13:707-723
A methyl‐Pt compound formed by incubating K2PtCl6 with methylcobalamin (MeB‐12) is further characterized with respect to its chloride content, its Pt oxidation state, and its electro‐phoretic mobility. The complexed chloride has been determined