Zobrazeno 1 - 10
of 608
pro vyhledávání: '"James A. Carroll"'
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/ce719585b7a74ff686d0c8c1896b8de2
Autor:
Simote T. Foliaki, Benjamin Schwarz, Bradley R. Groveman, Ryan O. Walters, Natalia C. Ferreira, Christina D. Orrù, Anna Smith, Aleksandar Wood, Olivia M. Schmit, Phoebe Freitag, Jue Yuan, Wenquan Zou, Catharine M. Bosio, James A. Carroll, Cathryn L. Haigh
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-23 (2021)
Abstract The neuro-physiological properties of individuals with genetic pre-disposition to neurological disorders are largely unknown. Here we aimed to explore these properties using cerebral organoids (COs) derived from fibroblasts of individuals wi
Externí odkaz:
https://doaj.org/article/6bd0dd66c2cd46cbb517d6bd6b03291d
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-23 (2021)
Abstract Background Past experiments studying innate immunity in the central nervous system (CNS) utilized microglia obtained from neonatal mouse brain, which differ developmentally from adult microglia. These differences might impact our current und
Externí odkaz:
https://doaj.org/article/19ac55a4bdac4bbd9432abef4403dd48
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-26 (2020)
Abstract Background Prion diseases and prion-like disorders, including Alzheimer’s disease and Parkinson’s disease, are characterized by gliosis and accumulation of misfolded aggregated host proteins. Ablating microglia in prion-infected brain by
Externí odkaz:
https://doaj.org/article/030e2056a940459dba0b82cc81e47223
Autor:
Bradley R. Groveman, Simote T. Foliaki, Christina D. Orru, Gianluigi Zanusso, James A. Carroll, Brent Race, Cathryn L. Haigh
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract For the transmissible, neurogenerative family of prion diseases, few human models of infection exist and none represent structured neuronal tissue. Human cerebral organoids are self-organizing, three-dimensional brain tissues that can be gro
Externí odkaz:
https://doaj.org/article/9d2522f5b8ef46879d6c6efd4b996b79
Autor:
James F. Striebel, Brent Race, Katie Williams, James A. Carroll, Mikael Klingeborn, Bruce Chesebro
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Degeneration of photoreceptors in the retina is a major cause of blindness in humans. Often retinal degeneration is due to inheritance of mutations in genes important in photoreceptor (PR) function, but can also be induced by other events in
Externí odkaz:
https://doaj.org/article/8472d92cf55f480c92b000fea3cb1737
Autor:
Brent Race, Katie Williams, Chase Baune, James F. Striebel, Clayton W. Winkler, James A. Carroll, Sandra E. Encalada, Bruce Chesebro
Publikováno v:
Viruses, Vol 13, Iss 7, p 1391 (2021)
In prion diseases, the spread of infectious prions (PrPSc) is thought to occur within nerves and across synapses of the central nervous system (CNS). However, the mechanisms by which PrPSc moves within axons and across nerve synapses remain undetermi
Externí odkaz:
https://doaj.org/article/ee9947329e504735bca8307e5764e9d5
Autor:
James A. Carroll, Bruce Chesebro
Publikováno v:
Viruses, Vol 11, Iss 1, p 65 (2019)
Prion disorders are transmissible diseases caused by a proteinaceous infectious agent that can infect the lymphatic and nervous systems. The clinical features of prion diseases can vary, but common hallmarks in the central nervous system (CNS) are de
Externí odkaz:
https://doaj.org/article/3d13575510494cdeae0420e1ed9ddd84
Autor:
Tammie L. Haley, Ryan M. Hecht, Gaoying Ren, James R. Carroll, Sue A. Aicher, Robert M. Duvoisin, Catherine W. Morgans
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
The ability of the visual system to relay meaningful information over a wide range of lighting conditions is critical to functional vision, and relies on mechanisms of adaptation within the retina that adjust sensitivity and gain as ambient light cha
Externí odkaz:
https://doaj.org/article/b2dc164038904b86bc98307ecd2f84df
Autor:
James D. Carroll
Publikováno v:
Photobiomodulation, Photomedicine, and Laser Surgery. 41:241-244