Zobrazeno 1 - 10
of 16
pro vyhledávání: '"James A. Bianco"'
Autor:
Stephen T. Sonis, Marcelo Bonomi, Rafi Kabarriti, Kyle Colvett, Bryan T. Oronsky, James A. Bianco, Dukagjin Blakaj, David J. Sher
Publikováno v:
Journal of Clinical Oncology. 38:12081-12081
12081 Background: SOM occurs in 70% of patients receiving CRT for HNC with consequent pain, treatment interruptions and increased costs of care. Supraphysiologic levels of oxidative stress are key SOM initiators. 001 activates nuclear factor erythroi
Autor:
Stefania Fatone, James Del Bianco
Publikováno v:
JPO Journal of Prosthetics and Orthotics. 20:155-162
Autor:
Jack W. Singer, Mark Groudine, Linda W. Wiens, G. William Demers, Tiep Le, Kenneth J. Russell, James A. Bianco, Denise A. Galloway, Glenn C. Rice
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 36:1099-1106
Purpose:To develop a checkpoint-based strategy for preferential radiosensitization of human tumors with deficient and/or mutant p53. Methods and Materials:A 549 human lung adenocarcinoma cell lines differing in their expression of the p53 tumor suppr
Autor:
Polly E. Parsons, David A. Federighi, Ward E. Harris, Ernest E. Jr Moore, John E. Repine, Edward Abraham, Jack W. Singer, F. A. Moore, Stuart L. Bursten, James A. Bianco
Publikováno v:
Critical Care Medicine. 24:1129-1136
No means exist for predicting the acute respiratory distress syndrome (ARDS), which complicates sepsis, trauma, and a variety of clinical disorders. Because activation of phospholipid-signaling pathways involving the acyl chains oleate and linoleate
Publikováno v:
Expert Opinion on Investigational Drugs. 3:631-644
Phosphatidic acids (PAs) are a molecularly diverse group of phospholipids. Certain species of PA are highly active intracellular signaling molecules associated with cellular activation and mitogenesis. Not surprisingly, the PA species active in signa
Autor:
Jack W. Singer, Glenn C. Rice, Paul A. Brown, Richard J. Nelson, James A. Bianco, Staurt Bursten
Publikováno v:
Proceedings of the National Academy of Sciences. 91:3857-3861
Certain phosphatidic/plasmanic/plasmenic acid (PA) species function as lipid intermediates in cell activation and may function directly as intracellular signaling molecules. PA can also be dephosphorylated to 1,2-diradyl-sn-glycerol by phosphatidate
Autor:
M C Benyunes, Catherine G. Lindgren, James A. Bianco, John A. Thompson, Anthony F. Shields, Alexander Fefer
Publikováno v:
Journal of Immunotherapy. 13:84-90
Pentoxifylline (PTX) is a methylated xanthine that has been shown to reduce the toxicity of Interleukin-2 (IL-2) therapy in animal models, possibly by inhibiting secretion of tumor necrosis factor-alpha. However, the use of PTX to reduce IL-2 toxicit
Publikováno v:
Leukemia & Lymphoma. 10:177-181
Cyclosporine and prednisone were administered as graft-versus-host disease (GVHD) prophylaxis to nine patients undergoing marrow transplant from HLA matched, unrelated donors. RhGM-CSF was administered at a dose of 250 micrograms/m2 daily to all pati
Autor:
Buckner Cd, F R Appelbaum, Jack W. Singer, A Fefer, William I. Bensinger, Clift Ra, P Beatty, William S. Dalton, James A. Bianco, Finn Bo Petersen
Publikováno v:
Journal of Clinical Oncology. 10:1492-1497
PURPOSE To study the toxicity and potential efficacy of busulfan (BU) and cyclophosphamide (CY) as a conditioning regimen before allogeneic bone marrow transplantation (ABMT) in patients with multiple myeloma (MM). PATIENTS AND METHODS Twenty patient
Autor:
Anthony Shields, Frank Andrews, James A. Bianco, Frederick R. Appelbaum, John Nemunaitis, Jeff Almgren, Jack Singer, Patrice Kettner
Publikováno v:
Blood. 78:1205-1211
Disease relapse and transplant related toxicities have limited the application of bone marrow transplantation (BMT) in the treatment for hematologic malignancies. Because elevated levels of tumor necrosis factor alpha (TNF-alpha) have been correlated