Zobrazeno 1 - 10
of 1 296
pro vyhledávání: '"James A Hall"'
Autor:
Carolin M Sauer, Katrin Heider, Jelena Belic, Samantha E Boyle, James A Hall, Dominique‐Laurent Couturier, Angela An, Aadhitthya Vijayaraghavan, Marika AV Reinius, Karen Hosking, Maria Vias, Nitzan Rosenfeld, James D Brenton
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 8, Pp n/a-n/a (2022)
Abstract Whole‐genome sequencing (WGS) of circulating tumour DNA (ctDNA) is now a clinically important biomarker for predicting therapy response, disease burden and disease progression. However, the translation of ctDNA monitoring into vital precli
Externí odkaz:
https://doaj.org/article/d7402f932e024ca29f08a4f9f317194b
Autor:
Carolin M. Sauer, James A. Hall, Dominique-Laurent Couturier, Thomas Bradley, Anna M. Piskorz, Jacob Griffiths, Ashley Sawle, Matthew D. Eldridge, Philip Smith, Karen Hosking, Marika A. V. Reinius, Lena Morrill Gavarró, Anne-Marie Mes-Masson, Darren Ennis, David Millan, Aoisha Hoyle, Iain A. McNeish, Mercedes Jimenez-Linan, Filipe Correia Martins, Julia Tischer, Maria Vias, James D. Brenton
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract High-grade serous ovarian carcinoma (HGSOC) is characterised by poor outcome and extreme chromosome instability (CIN). Therapies targeting centrosome amplification (CA), a key mediator of chromosome missegregation, may have significant clini
Externí odkaz:
https://doaj.org/article/2dec6d7efd4243ae9b8168a692f69967
Autor:
Ysobel R. Baker, Cameron Thorpe, Jinfeng Chen, Laura M. Poller, Lina Cox, Pawan Kumar, Wooi F. Lim, Lillian Lie, Graham McClorey, Sven Epple, Daniel Singleton, Michael A. McDonough, Jack S. Hardwick, Kirsten E. Christensen, Matthew J. A. Wood, James P. Hall, Afaf H. El-Sagheer, Tom Brown
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Oligonucleotides targeting mRNA are promising therapeutic agents but suffer from poor bioavailability. Here, the authors develop reduced-charge oligonucleotides with artificial LNA-amide linkages with improved cell uptake and minimal structural devia
Externí odkaz:
https://doaj.org/article/9f5986b8806645e7a8826174637171fa
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundDue to their low cost, less invasive nature, and ready availability, plasma biomarkers of Alzheimer's disease have been proposed as one-time screening tools for clinical trials and research. The impact of ethnoracial factors on these biomar
Externí odkaz:
https://doaj.org/article/2ed3a48e1ee444aabc5b4b43b9b116a8
Autor:
James J. Yu, Amy L. Non, Erica C. Heinrich, Wanjun Gu, Joe Alcock, Esteban A. Moya, Elijah S. Lawrence, Michael S. Tift, Katie A. O'Brien, Jay F. Storz, Anthony V. Signore, Jane I. Khudyakov, William K. Milsom, Sean M. Wilson, Cynthia M. Beall, Francisco C. Villafuerte, Tsering Stobdan, Colleen G. Julian, Lorna G. Moore, Mark M. Fuster, Jennifer A. Stokes, Richard Milner, John B. West, Jiao Zhang, John Y. Shyy, Ainash Childebayeva, José Pablo Vázquez-Medina, Luu V. Pham, Omar A. Mesarwi, James E. Hall, Zachary A. Cheviron, Jeremy Sieker, Arlin B. Blood, Jason X. Yuan, Graham R. Scott, Brinda K. Rana, Paul J. Ponganis, Atul Malhotra, Frank L. Powell, Tatum S. Simonson
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The ability to respond rapidly to changes in oxygen tension is critical for many forms of life. Challenges to oxygen homeostasis, specifically in the contexts of evolutionary biology and biomedicine, provide important insights into mechanisms of hypo
Externí odkaz:
https://doaj.org/article/ad6281793d794d10a1e325e2249296a9
Autor:
Olaitan E. Oladipupo, Meredith C. Prescott, Emily R. Blevins, Jessica L. Gray, Colin G. Cameron, Fengrui Qu, Nicholas A. Ward, Abigail L. Pierce, Elizabeth R. Collinson, James Fletcher Hall, Seungjo Park, Yonghyun Kim, Sherri A. McFarland, Igor Fedin, Elizabeth T. Papish
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5980 (2023)
Protic ruthenium complexes using the dihydroxybipyridine (dhbp) ligand combined with a spectator ligand (N,N = bpy, phen, dop, Bphen) have been studied for their potential activity vs. cancer cells and their photophysical luminescent properties. Thes
Externí odkaz:
https://doaj.org/article/5d9fedf841fa43a684e48868afd73f1d
Publikováno v:
Journal of Psychophysiology. 37:110-121
Abstract: A critical review was conducted to examine whether the peripheral hearing status of participants with neurological and psychological disorders was documented in published clinical studies of the auditory P300 response. Literature searches w
Autor:
Vidya Ramkumar, Roopa Nagarajan, Vanaja C. Shankarnarayan, Selvakumar Kumaravelu, James W. Hall
Publikováno v:
BMC Health Services Research, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background In an attempt to reach remote rural areas, this study explores a community-based, pediatric hearing screening program in villages, integrating two models of diagnostic ABR testing; one using a tele-medicine approach and the other
Externí odkaz:
https://doaj.org/article/b629e1f2436e4e63a1eaf58016dc5b3a
Autor:
Sid E. O'Bryant, Leigh A. Johnson, Robert C. Barber, Meredith N. Braskie, Bradley Christian, James R. Hall, Nalini Hazra, Kevin King, Deydeep Kothapalli, Stephanie Large, David Mason, Elizabeth Matsiyevskiy, Roderick McColl, Rajesh Nandy, Raymond Palmer, Melissa Petersen, Nicole Philips, Robert A. Rissman, Yonggang Shi, Arthur W. Toga, Raul Vintimilla, Rocky Vig, Fan Zhang, Kristine Yaffe, for the HABLE Study Team
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 13, Iss 1, Pp n/a-n/a (2021)
Abstract Introduction Mexican Americans remain severely underrepresented in Alzheimer's disease (AD) research. The Health & Aging Brain among Latino Elders (HABLE) study was created to fill important gaps in the existing literature. Methods Community
Externí odkaz:
https://doaj.org/article/32c6a2cb86ac4675a0b0351004c82687
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Over millions of years, vertebrate species populated vast environments spanning the globe. Among the most challenging habitats encountered were those with limited availability of oxygen, yet many animal and human populations inhabit and perform life
Externí odkaz:
https://doaj.org/article/7eb6eb0476404cfbb299efde9cedc7ac