Zobrazeno 1 - 10
of 100
pro vyhledávání: '"James A Grogan"'
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 3, p e1006049 (2018)
The corneal micropocket angiogenesis assay is an experimental protocol for studying vessel network formation, or neovascularization, in vivo. The assay is attractive due to the ease with which the developing vessel network can be observed in the same
Externí odkaz:
https://doaj.org/article/7a94720943d44f388489afde2ee63191
Autor:
Tracey A. H. Taylor, Suzan Kamel-ElSayed, James F. Grogan, Inaya Hajj Hussein, Sarah Lerchenfeldt, Changiz Mohiyeddini
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
The COVID-19 pandemic caused an unprecedented and highly threatening, constrained, and confusing social and educational environment, we decided to expand the traditional focus of the extraneous load in Cognitive Load Theory (CLT) acknowledging the ps
Externí odkaz:
https://doaj.org/article/66564a8fce3d44c7b5a4c7de77ead627
Autor:
Timm Krüger, Philip K. Maini, Miguel O. Bernabeu, Tomás Alarcón, Jakub Köry, Joe Pitt-Francis, Helen M. Byrne, Bostjan Markelc, James A. Grogan, Jakob Kaeppler, Albert Beardo Ricol, Ruth J. Muschel, Nicholas Daly, Mayeul d'Avezac, James Hetherington
Publikováno v:
Bernabeu, M O, Köry, J, Grogan, J A, Markelc, B, Beardo, A, d'Avezac, M, Enjalbert, R, Kaeppler, J, Daly, N, Hetherington, J, Krüger, T, Maini, P K, Pitt-Francis, J M, Muschel, R J, Alarcón, T & Byrne, H M 2020, ' Abnormal morphology biases hematocrit distribution in tumor vasculature and contributes to heterogeneity in tissue oxygenation ', Proceedings of the National Academy of Sciences of the United States of America . https://doi.org/10.1073/pnas.2007770117
Proceedings of the National Academy of Sciences of the United States of America
Bernabeu, M O, Köry, J, Grogan, J A, Markelc, B, Beardo, A, d'Avezac, M, Enjalbert, R, Kaeppler, J, Daly, N, Hetherington, J, Krüger, T, Maini, P K, Pitt-Francis, J M, Muschel, R J, Alarcón, T & Byrne, H M 2020, ' Abnormal morphology biases haematocrit distribution in tumour vasculature and contributes to heterogeneity in tissue oxygenation ', Proceedings of the National Academy of Sciences . https://doi.org/10.1073/pnas.2007770117
Proceedings of the National Academy of Sciences of the United States of America
Bernabeu, M O, Köry, J, Grogan, J A, Markelc, B, Beardo, A, d'Avezac, M, Enjalbert, R, Kaeppler, J, Daly, N, Hetherington, J, Krüger, T, Maini, P K, Pitt-Francis, J M, Muschel, R J, Alarcón, T & Byrne, H M 2020, ' Abnormal morphology biases haematocrit distribution in tumour vasculature and contributes to heterogeneity in tissue oxygenation ', Proceedings of the National Academy of Sciences . https://doi.org/10.1073/pnas.2007770117
Significance Oxygen heterogeneity in solid tumors is recognized as a limiting factor for therapeutic efficacy. This heterogeneity arises from the abnormal tumor vascular structure. We investigate the role that anomalies in red blood cell transport pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5536ea5d9f478019dacf5a6d8efbb01d
https://ora.ox.ac.uk/objects/uuid:f06be3bb-cb58-4fdb-8f88-e5867148d1bf
https://ora.ox.ac.uk/objects/uuid:f06be3bb-cb58-4fdb-8f88-e5867148d1bf
Autor:
Valentina Carapella, Daniel G. Harvey, Alexander G. Fletcher, Beth McMillan, Fergus R. Cooper, Rafel Bordas, Wenxian Guo, Maurice Hendrix, Blanca Rodriguez, Louise Bowler, James M. Osborne, Philip K. Maini, Benjamin D. Evans, Helen M. Byrne, Gary R. Mirams, Miguel O. Bernabeu, Jochen Kursawe, Joe Pitt-Francis, Louie Cardone-Noott, Ruth E. Baker, James A. Grogan, Pras Pathmanathan, Sara Dutta, Martin Robinson, David J. Gavaghan, Raymond J. Spiteri, Alfonso Bueno-Orovio, David Kay, Jonathan Cooper
Funding: UK Engineering and Physical Sciences Research Council [grant number EP/N509711/1 (J.K.)]. Chaste (Cancer, Heart And Soft Tissue Environment) is an open source simulation package for the numerical solution of mathematical models arising in ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9587bddfd8b330f72b7170c8b8a3a617
https://ora.ox.ac.uk/objects/uuid:4c101927-cdb1-4e16-b259-cc244a5e7d62
https://ora.ox.ac.uk/objects/uuid:4c101927-cdb1-4e16-b259-cc244a5e7d62
Autor:
James A. Grogan, Peter E. McHugh, Mark Bruzzi, Caoimhe A. Sweeney, Barry O'brien, Donnacha J. McGrath, Stefan Jockenhoevel, Nicola Kelly, Kathrin Kurtenbach
Publikováno v:
Computer Methods in Biomechanics and Biomedical Engineering, 22(16), 1334-1344. Routledge/Taylor & Francis Group
Braided stents are associated with a number of complications in vivo. Accurate computational modelling of these devices is essential for the design and development of the next generation of these stents. In this study, two commonly utilised methods o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb30a65a8d35e89a5fc50ed9b19db5ac
https://cris.maastrichtuniversity.nl/en/publications/e03aaba3-0057-4548-b08e-5330b0ebbfe0
https://cris.maastrichtuniversity.nl/en/publications/e03aaba3-0057-4548-b08e-5330b0ebbfe0
Autor:
James A. Grogan, Simone Bnà, Daniele Tartarini, Stelios Sfakianakis, Marco Viceconti, Debora Testi, Dawn Walker, Samuel Gamble
Publikováno v:
Journal of Computational Science. 25:101-114
Computational medicine more and more requires complex orchestrations of multiple modelling & simulation codes, written in different programming languages and with different computational requirements, which when validated need to be run many times on
Autor:
Ruth J. Muschel, James A. Grogan, Philip K. Maini, Bostjan Markelc, Helen M. Byrne, Anthony J. Connor, Joe Pitt-Francis
Publikováno v:
Biophysical Journal
Spatial models of vascularized tissues are widely used in computational physiology, to study for example, tumour growth, angiogenesis, osteogenesis, coronary perfusion and oxygen delivery. Composition of such models is time-consuming, with many resea
Publikováno v:
International Journal for Numerical Methods in Biomedical Engineering. 35
Significant research has been conducted in the area of coronary stents/scaffolds made from resorbable metallic and polymeric biomaterials. These next-generation bioabsorbable stents have the potential to completely revolutionise the treatment of coro
Publikováno v:
JOM. 68:1198-1203
Coronary stents have revolutionised the treatment of coronary artery disease. While coronary artery stenting is now relatively mature, significant scientific and technological challenges still remain. One of the most fertile technological growth area
Publikováno v:
Journal of Medical Devices. 11
Coronary stents made from degradable biomaterials such as magnesium alloy are an emerging technology in the treatment of coronary artery disease. Biodegradable stents provide mechanical support to the artery during the initial scaffolding period afte