Zobrazeno 1 - 10
of 1 208
pro vyhledávání: '"James A Foster"'
Autor:
Patric M Vaelli, Kevin R Theis, Janet E Williams, Lauren A O'Connell, James A Foster, Heather L Eisthen
Publikováno v:
eLife, Vol 9 (2020)
Rough-skinned newts (Taricha granulosa) use tetrodotoxin (TTX) to block voltage-gated sodium (Nav) channels as a chemical defense against predation. Interestingly, newts exhibit extreme population-level variation in toxicity attributed to a coevoluti
Externí odkaz:
https://doaj.org/article/3a53a6c7fc7d494a8851e0d070ff651f
Autor:
Abigail R Moye, Nicola Bedoni, Jessica G Cunningham, Urikhan Sanzhaeva, Eric S Tucker, Peter Mathers, Virginie G Peter, Mathieu Quinodoz, Liliana P Paris, Luísa Coutinho-Santos, Pedro Camacho, Madeleine G Purcell, Abbie C Winkelmann, James A Foster, Elena N Pugacheva, Carlo Rivolta, Visvanathan Ramamurthy
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008315 (2019)
Cilia are evolutionarily conserved hair-like structures with a wide spectrum of key biological roles, and their dysfunction has been linked to a growing class of genetic disorders, known collectively as ciliopathies. Many strides have been made towar
Externí odkaz:
https://doaj.org/article/480975d5e12444a18eb9f8d47c79cac6
Autor:
Amirthagowri Ambalavanan, Le Chang, Jihoon Choi, Yang Zhang, Sara A. Stickley, Zhi Y. Fang, Kozeta Miliku, Bianca Robertson, Chloe Yonemitsu, Stuart E. Turvey, Piushkumar J. Mandhane, Elinor Simons, Theo J. Moraes, Sonia S. Anand, Guillaume Paré, Janet E. Williams, Brenda M. Murdoch, Gloria E. Otoo, Samwel Mbugua, Elizabeth W. Kamau-Mbuthia, Egidioh W. Kamundia, Debela K. Gindola, Juan M. Rodriguez, Rossina G. Pareja, Daniel W. Sellen, Sophie E. Moore, Andrew M. Prentice, James A. Foster, Linda J. Kvist, Holly L. Neibergs, Mark A. McGuire, Michelle K. McGuire, Courtney L. Meehan, Malcolm R. Sears, Padmaja Subbarao, Meghan B. Azad, Lars Bode, Qingling Duan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Breastfeeding provides many health benefits, but its impact on respiratory health remains unclear. This study addresses the complex and dynamic nature of the mother-milk-infant triad by investigating maternal genomic factors regulating human
Externí odkaz:
https://doaj.org/article/d7c0e875da6b483985a0dffeae48ad19
Autor:
Trevor J. Hancock, Marina Vlasyuk, James S. Foster, Sallie Macy, Daniel C. Wooliver, Manasi Balachandran, Angela D. Williams, Emily B. Martin, Stephen J. Kennel, Eric R. Heidel, Jonathan S. Wall, Joseph W. Jackson
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAmyloid-specific antibodies have been shown to opsonize and enhance amyloid clearance in systemic amyloidosis mouse models. However, the immunological mechanisms by which amyloid is removed have not been clearly defined. Previous reports
Externí odkaz:
https://doaj.org/article/4538e96b6e1444728c5563af79f43964
Autor:
Daniel Beck, James A Foster
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87830 (2014)
Microbial communities are important to human health. Bacterial vaginosis (BV) is a disease associated with the vagina microbiome. While the causes of BV are unknown, the microbial community in the vagina appears to play a role. We use three different
Externí odkaz:
https://doaj.org/article/c19693f0b0394f83833b35dfcc56182e
Autor:
Katherine M Hunt, James A Foster, Larry J Forney, Ursel M E Schütte, Daniel L Beck, Zaid Abdo, Lawrence K Fox, Janet E Williams, Michelle K McGuire, Mark A McGuire
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21313 (2011)
Recent investigations have demonstrated that human milk contains a variety of bacterial genera; however, as of yet very little work has been done to characterize the full diversity of these milk bacterial communities and their relative stability over
Externí odkaz:
https://doaj.org/article/3a86ab682ef24970ab0361e99c5b5df2
Autor:
Stephen J Kennel, Joseph W Jackson, Alan Stuckey, Tina Richey, James S Foster, Jonathan S Wall
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301756 (2024)
IntroductionAmyloid deposition is a cause of restrictive cardiomyopathy. Patients who present with cardiac disease can be evaluated for transthyretin (TTR)-associated cardiac amyloidosis using nuclear imaging with 99mTc-labeled pyrophosphate (PYP); h
Externí odkaz:
https://doaj.org/article/ae00333921e540a68f07fb68eada90da
Autor:
James S. Foster, Manasi Balachandran, Trevor J. Hancock, Emily B. Martin, Sallie Macy, Craig Wooliver, Tina Richey, Alan Stuckey, Angela D. Williams, Joseph W. Jackson, Stephen J. Kennel, Jonathan S. Wall
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSystemic amyloidosis is a progressive disorder characterized by the extracellular deposition of amyloid fibrils and accessory proteins in visceral organs and tissues. Amyloid accumulation causes organ dysfunction and is not generally clea
Externí odkaz:
https://doaj.org/article/3ce636148a204e3aafd0f0efaec0fd54
Autor:
Céline Portal, Yvonne Lin, Varuni Rastogi, Cornelia Peterson, Samuel Chi-Hung Yiu, James W. Foster, Amber Wilkerson, Igor A. Butovich, Carlo Iomini
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Meibomian gland (MG) cells are ciliated in early stages of development and primary cilium is required to regulate early MG cell patterning within developing glands, with cilia-mediated signaling pathways identified as therapeutic targets.
Externí odkaz:
https://doaj.org/article/1c246975864b4059b4eaf087504751f5
Autor:
Madhur Shetty, Danielle E. Bolland, Joshua Morrell, Bryon D. Grove, James D. Foster, Roxanne A. Vaughan
Publikováno v:
Current Research in Physiology, Vol 6, Iss , Pp 100106- (2023)
The primary regulator of dopamine availability in the brain is the dopamine transporter (DAT), a plasma membrane protein that drives reuptake of released dopamine from the extracellular space into the presynaptic neuron. DAT activity is regulated by
Externí odkaz:
https://doaj.org/article/2cd3ce10da6d4b5ab18d57d3cadadfb7