Zobrazeno 1 - 10
of 22
pro vyhledávání: '"James A, Oakes"'
Publikováno v:
Journal of Endocrinology. 247:197-212
The roles of androgens in male reproductive development and function in zebrafish are poorly understood. To investigate this topic, we employed CRISPR/Cas9 to generate cyp11c1 (11β-hydroxylase) mutant zebrafish lines. Our study confirms recently pub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf597686cb8bbad23a576548090ce469
https://doi.org/10.1530/joe-20-0160
https://doi.org/10.1530/joe-20-0160
Publikováno v:
The Journal of endocrinology. 244(2)
Cytochrome P450 side-chain cleavage enzyme, encoded by the CYP11A1 gene, catalyzes the first and rate-limiting step of steroid hormone biosynthesis. Previous morpholino-knockdown studies in zebrafish suggested cyp11a2 is a functional equivalent of hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9781ae13981dcea8a640234cec2adfd3
https://pubmed.ncbi.nlm.nih.gov/31693487
https://pubmed.ncbi.nlm.nih.gov/31693487
Autor:
Aliesha Griffin, James A Oakes, Belinda Wistow, Lise Barnard, Nan Li, Karl-Heinz Storbeck, Vincent T. Cunliffe, Nils Krone
Publikováno v:
Endocrinology. 160(10)
The roles of steroids in zebrafish sex differentiation, gonadal development, and function of the adult gonad are poorly understood. Herein, we used ferredoxin 1b (fdx1b) mutant zebrafish to explore such processes. Fdx1b is an essential electron-provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ebc13389f2ebce5a61b5d4d6171c91
https://pubmed.ncbi.nlm.nih.gov/31322700
https://pubmed.ncbi.nlm.nih.gov/31322700
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8834ff33ff47eb6e915b9ed42db5a80a
https://doi.org/10.1530/endoabs.59.p194
https://doi.org/10.1530/endoabs.59.p194
Autor:
Helen, Eachus, Andreas, Zaucker, James A, Oakes, Aliesha, Griffin, Meltem, Weger, Tülay, Güran, Angela, Taylor, Abigail, Harris, Andy, Greenfield, Jonathan L, Quanson, Karl-Heinz, Storbeck, Vincent T, Cunliffe, Ferenc, Müller, Nils, Krone
Publikováno v:
Endocrinology
Congenital adrenal hyperplasia is a group of common inherited disorders leading to glucocorticoid deficiency. Most cases are caused by 21-hydroxylase deficiency (21OHD). The systemic consequences of imbalanced steroid hormone biosynthesis due to seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::30bdc64aabec5c3f8fdb083baaf8846f
https://pubmed.ncbi.nlm.nih.gov/28938470
https://pubmed.ncbi.nlm.nih.gov/28938470
Publikováno v:
Molecular Brain
Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disorder affecting motor neurons, resulting in progressive muscle weakness and death by respiratory failure. Protein and RNA aggregates are a hallmark of ALS pathology and are th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57fcf922df782f3e1c15fdeace6c2c7b
http://europepmc.org/articles/PMC5288885
http://europepmc.org/articles/PMC5288885
Autor:
Nils Krone, Helen Eachus, Ferenc Müller, J.L. Do Rego, Philipp Gut, Andreas Zaucker, Karl-Heinz Storbeck, James A Oakes, Tanja Beil, Sepand Rastegar, Benjamin D. Weger, Meltem Weger, Nicolas Diotel, Uwe Strähle
Publikováno v:
Journal of neuroendocrinology. 30(4)
The spatial and temporal expression of steroidogenic genes in zebrafish has not been fully characterised. Because zebrafish are increasingly employed in endocrine and stress research, a better characterisation of steroidogenic pathways is required to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b08ca3ea55c733fbc978ed388c2f245
https://pubmed.ncbi.nlm.nih.gov/29486070
https://pubmed.ncbi.nlm.nih.gov/29486070
Publikováno v:
Journal of Healthcare Engineering, Vol 2, Iss 1, Pp 43-53 (2011)
This paper proposes a method for examining the causal relationship among investment in information technology (IT) and the organization's productivity. In this method, first a strong relationship among (1) investment in IT, (2) use of IT and (3) orga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee60647528e2cbb167370a1f7ce94b1
https://doi.org/10.1260/2040-2295.2.1.43
https://doi.org/10.1260/2040-2295.2.1.43
Autor:
James L. Oakes
Publikováno v:
Federal Sentencing Reporter. 5:10-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f81ab640d98023fe3dd854df00c5792
https://doi.org/10.2307/20639496
https://doi.org/10.2307/20639496
Autor:
James L. Oakes
Publikováno v:
Federal Sentencing Reporter. 5:52-57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::851ee8a056caacddff2c97f302929a7a
https://doi.org/10.2307/20639506
https://doi.org/10.2307/20639506