Zobrazeno 1 - 10
of 151
pro vyhledávání: '"James A, Gow"'
Autor:
Ta Yuan Chang, Catherine C. Y. Chang, Taylor C. Harned, Adrianna L. De La Torre, Junghoon Lee, Thao N. Huynh, James G. Gow
Publikováno v:
Exploration of Neuroprotective Therapy, Vol 1, Iss 3, Pp 173-184 (2021)
Cholesterol serves as an essential lipid molecule in various membrane organelles of mammalian cells. The metabolites of cholesterol also play important functions. Acyl-coenzyme A: cholesterol acyltransferase 1 (ACAT1), also named as sterol O-acyltran
Externí odkaz:
https://doaj.org/article/a718787065e249078cafd7c261450165
Autor:
Haibo Li, Thao N. Huynh, Michael Tran Duong, James G. Gow, Catherine C. Y. Chang, Ta Yuan Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5616 (2023)
Cholesterol is stored as cholesteryl esters by the enzymes acyl-CoA:cholesterol acyltransferases/sterol O:acyltransferases (ACATs/SOATs). ACAT1 blockade (A1B) ameliorates the pro-inflammatory responses of macrophages to lipopolysaccharides (LPS) and
Externí odkaz:
https://doaj.org/article/80a218ca3938496ea99e8c8315841209
Autor:
Jacques Bourgault, James Iain Gow
Publikováno v:
Revue Internationale des Sciences Administratives. 88:281-299
Publikováno v:
Applied In Vitro Toxicology. 6:90-98
Introduction: Recognition of fungal surface β-glucan by pattern recognition receptor Dectin-1 is a critical process for fungal clearance in the lung. In humans, persistent fungal infection is observed in individuals with particular Dectin-1 polymorp
Autor:
Jacques Bourgault, James Iain Gow
Publikováno v:
International Review of Administrative Sciences. 88:302-319
A survey of Canada’s top public servants was used to test the effects on them of the agency version of the public service bargain held by the Conservative government of Stephen Harper (2006–2015). Most results were as expected: increasing politic
Autor:
Elena Abramova, Alexa Murray, Thea N. Golden, Debra L. Laskin, Rama Malaviya, Andrew J. Gow, Sheryse Taylor, Alessandro Venosa, James G. Gow
Publikováno v:
Toxicol Appl Pharmacol
Bleomycin is a cancer therapeutic known to cause lung injury which progresses to fibrosis. Evidence suggests that macrophages contribute to this pathological response. Tumor necrosis factor (TNF)α is a macrophage-derived pro-inflammatory cytokine im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68bb14094ccf6629ad3b140b0ee384c5
https://europepmc.org/articles/PMC10157853/
https://europepmc.org/articles/PMC10157853/
Publikováno v:
Orphanet Journal of Rare Diseases
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-12 (2020)
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-12 (2020)
Background Rare disease patients often struggle to find both medical advice and emotional support for their diagnosis. Consequently, many rare disease patient support forums have appeared on hospital webpages, social media sites, and on rare disease
Autor:
Rama Malaviya, Jeffrey D. Laskin, Debra L. Laskin, LeRoy Hall, Andrew J. Gow, James G. Gow, Alessandro Venosa
Publikováno v:
Toxicological Sciences. 157:222-234
Nitrogen mustard (NM)-induced lung injury is associated with an accumulation of proinflammatory/cytotoxic M1 and antiinflammatory/wound repair M2 macrophages, which have been implicated in tissue injury and repair. Herein, we analyzed the effects of